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 TERMINÉ 
The Internet has revolutionalized the way people and corporations communicate, publish, access, and search for information. As our globally-connected digital civilization increasingly relies on its smooth operation any disruption has a direct negative impact on both the economy and society. However, the Internet was not designed to serve its current role nor was foreseen to be a public good. On th ...
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 1

 TERMINÉ 

Federation for FIRE Plus (Fed4FIREplus)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

The Fed4FIRE+ project has the objective to run and further improve Fed4FIRE’s “best-in-town” federation of experimentation facilities for the Future Internet Research and Experimentation initiative. Federating a heterogeneous set of facilities covering technologies ranging from wireless, wired, cloud services and open flow, and making them accessible through common frameworks and tools suddenly op ...
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 24

 TERMINÉ 

Fostering responsive mental health systems in the Syrian refugee crisis (STRENGTHS)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

STRENGTHS aims to provide effective community-based health care implementation strategies to scale-up the delivery and uptake of effective mental health interventions in different country contexts. The current refugee crisis across Europe and the Middle East effects both individual refugees’ psychological well-being, as they face extreme stressors in their flight from their home country, but also ...
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 15

 TERMINÉ 

Human Puripotent Stem Cell Registry (hPSCreg)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

European registry for human embryonic stem cell lines
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 2

 TERMINÉ 

Big Data Management and Analytics

Date du début: 1 sept. 2016, Date de fin: 31 oct. 2021,

...us data for decision-making purposes. The curriculum is jointly delivered by Université libre de Bruxelles (ULB), Belgium, Universitat Politècnica de Catalunya (UPC), Spain, Technische Universität Berlin (TUB), Germany, Technische Universiteit Eindhoven (TU/e), the Netherlands, and Université François Rabelais Tours (UFRT), France. Academic partners around the world and partners from leading indus ...
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 5

 TERMINÉ 
A major goal in ecology is to predict how environmental changes, including drivers of global change, affect communities and ecosystem functioning, with society demanding answers to these pressing questions. A key limitation of virtually all experimental approaches addressing such questions is that treatments are delivered abruptly, while many changes occurring in nature are gradual. Here I propose ...
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 1

 TERMINÉ 

The Multimedia Yasna (MUYA)

Date du début: 1 oct. 2016, Date de fin: 30 sept. 2021,

What exactly are the words which priests recite in the Yasna, the core ritual of one of the most ancient and influential living religions, Zoroastrianism? What is their meaning and how do they relate to the ritual actions? The Yasna is significant for our cultural heritage not only because of its influential thought system which arguably impacted on post-exilic Judaism, nascent Christianity and Is ...
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 4

 TERMINÉ 
The long-term consequences of exposure to excess stress on the initiation and progression of many age-related diseases are well established. The period of intrauterine life represents among the most sensitive developmental windows, at which time the effects of stress may be transmitted inter-generationally from a mother to her as-yet-unborn child. The elucidation of mechanisms underlying such effe ...
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 1

 TERMINÉ 

NEURASMUS : A EUROPEAN MASTER IN NEUROSCIENCE : ADVANCED COURSE AND RESEARCH TRAINING

Date du début: 1 sept. 2016, Date de fin: 31 août 2021,

...ije Universiteit Amsterdam (Neurogenomics); 2) Université de Bordeaux (Neuropharmacology); 3) Georg-August-Universität Göttingen (Neurophysiology and Imaging); 4) Charité - Universitätsmedizin Berlin, Freie Universität und Humboldt - Universität zu Berlin (Clinical Neuroimaging and Translational Research); 5) Université Laval, Québec (Neurophotonics). As a joint international programme, Neurasmus ...
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 5

 TERMINÉ 

Geometric aspects in pathwise stochastic analysis and related topics (GPSART)

Date du début: 1 sept. 2016, Date de fin: 31 août 2021,

"Recent years have seen an explosion of applications of geometric and pathwise ideas in probability theory, with motivations from fields as diverse as quantitative finance, statistics, filtering, control theory and statistical physics. Much can be traced back to Bismut, Malliavin (1970s) on the one-hand and then Doss, Sussman (1970s), Foellmer (1980s) on the other hand, with substantial new input ...
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 2

 TERMINÉ 

Life Integrated Process for the Enzymatic Splitting of triglycerides (LIPES)

Date du début: 1 sept. 2016, Date de fin: 31 août 2021,

The overall purpose of the proposal LIPES, Life Integrated Process for the Enzymatic Splitting of triglycerides, is dedicated to the first market replication of greener and healthier fatty acids motivated by an increasing market demand and driven by stricter legislation. LIPES aims to perform the scale-up to pre-industrial level of a new environmentally friendly alternative to the traditional and ...
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 5

 TERMINÉ 
Background. We have detailed maps of brain structure and function, yet are lacking understanding of how the highly connected units interact and give rise to mental processes. The Virtual Brain (TVB), a whole brain simulation framework, aims to bridge that gap. Yet it is still developing. We are proposing here breakthrough advances that reveal mechanisms of brain function and foster collaboration b ...
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 1

 TERMINÉ 

Allocation Made PracticaL (AMPLify)

Date du début: 1 juin 2016, Date de fin: 31 mai 2021,

Allocation Made PracticaLThe AMPLify project will lay the foundations of a new field, computational behavioural game theory that brings a computational perspective, computational implementation, and behavioural insights to game theory. These foundations will be laid by tackling a pressing problem facing society today: the efficient and fair allocation of resources and costs. Research in allocation ...
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 1

 TERMINÉ 
"The BIOCYCLE Project proposes to test and critically assess the benefits and risks of an innovative regimen for improving the treatment of Crohn’s disease (CD), a chronic immune-mediated inflammatory disease affecting the gastro-intestinal tract of an increasing number of patients. Currently, the combination of anti-TNFα monoclonal antibodies and immunosuppressants used without interruption is th ...
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 13

 TERMINÉ 
Herpesviruses cause serious diseases in humans and animals. After initial lytic infection, herpesviruses establish a quiescent (latent) infection, which allows their persistence in the host for life. We and others recently identified a novel mechanism that allows maintenance of the genome of certain herpesviruses during latency, by integrating their complete genetic material into host telomeres. O ...
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 1

 TERMINÉ 

The European network for observing our changing planet (ERA-PLANET)

Date du début: 1 févr. 2016, Date de fin: 31 janv. 2021,

In the last decade a significant number of projects and programmes in different domains of environmental monitoring and Earth observation have generated a substantial amount of data and knowledge on different aspects related to environmental quality and sustainability. Big data generated by in-situ or satellite platforms are being collected and archived with a plethora of systems and instruments m ...
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 38

 TERMINÉ 

Localized Surface Plasmon Resonance in doped semiconductor nanocrystals (SONAR)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Doped semiconductor nanocrystals (dSNCs) are an exciting emerging material. Carrier densities in the range of 1020-1021cm-3 lead to localized surface plasmon resonances (LSPRs) in the near infrared (NIR). Prominent examples are copper chalcogenides, where doping occurs via vacancy formation, and metal oxides (MOs) that show plasmonic response due to impurity doping. Excitingly, both materials disp ...
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 4

 TERMINÉ 
Experimentation in mesocosms is arguably the single most powerful approach to obtain a mechanistic quantitative understanding of ecosystem-level impacts of stressors in complex systems, especially when embedded in long-term observations, theoretical models and experiments conducted at other scales. AQUACOSM builds on an established European network of mesocosm research infrastructures (RI), the FP ...
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 23

 TERMINÉ 
PACE aims to transform the treatment of patients suffering from critical limb ischemia (CLI), a disease with high medical need, because of limited treatment options and poor outcome by applying a novel, off-the-shelf allogeneic placenta-derived stromal cell product (PLX-PAD). Despite improvements in medical care and revascularization, patients with CLI continue to have a high risk of major amputat ...
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 9

 TERMINÉ 
Background According to the International Union for Conservation of Nature (IUCN), sturgeons are the most threatened fish species worldwide. Of the five surviving sturgeon species in the Danube basin, the IUCN Red List categorises four as “critically endangered” and one as “vulnerable”. Population trends for all five are decreasing. Within the EU, ...
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 9

 TERMINÉ 
The objective of the project PECSYS is the demonstration of a system for the solar driven electrochemical hydrogen generation with an area >10 m². The efficiency of the system will be >6% and it will operate for six month showing a degradation below 100 cm²) and will be subject to extensive stability optimization. Especially, the use of innovative ALD based metal oxide sealing layers will be studi ...
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 6

 TERMINÉ 

The Post-crisis Legitimacy of the European UnionEuropean Training Network (PLATO)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Is there a crisis in the legitimacy of the European Union? That research question is timely and important. Investigating it is also an ideal way of training research leaders of tomorrow to rethink our assumptions about the study of legitimate political order. Whilst, however, the financial crisis has raised new questions about the legitimacy of the EU, existing theories of legitimacy crises are la ...
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 9

 TERMINÉ 

Drug Discovery and Delivery NEtwork for ONcology and Eye Therapeutics (3D NEONET)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Severe ocular disorders are affecting the lives of more than 100Mill people world-wide and at least 25% of the population above 70 years of age, a growing demographic group in EU. More than 8 million people lose their lives to cancer every year, making cancer a leading cause of pre-mature mortality in the world. The main hallmarks of severe eye conditions (i.e angiogenesis, inflammation and vascul ...
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 18

 TERMINÉ 

Active dendrites and cortical associations (ActiveCortex)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

Converging studies from psychophysics in humans to single-cell recordings in monkeys and rodents indicate that most important cognitive processes depend on both feed-forward and feedback information interacting in the brain. Intriguingly, feedback to early cortical processing stages appears to play a causal role in these processes. Despite the central nature of this fact to understanding brain cog ...
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 1

 TERMINÉ 

Reactions That Translate mRNA into Drug-like Molecules (TRIGGDRUG)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

How could a molecular cancer therapy look like in 2040? In cancer, gene expression is deregulated due to amplification, mutation and translocation of genes. Next generation RNA sequencing provides us with the opportunity to identify the number and identity of the gene products aberrantly expressed in a patient. But do we have methods that take advantage of the personalized sequence data? In this r ...
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 1

 TERMINÉ 
Environmental perturbations to lakes and reservoirs occur largely as episodic climatic events. These range from relatively short mixing events to storms and heat waves. While the driving events occur along a continuum of frequency and magnitude, however, their effect is generally longer lasting than the events themselves. In addition, the more extreme weather events are now becoming increasingly ...
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 8

 TERMINÉ 
Regulators and industries are challenged by the difficulty to analyse and predict the impact of nonlinear environmental processes on short-term and long-term responses of ecosystems to environmental change. Until very recently, the development of most conventional monitoring, forecasting and prediction tools has been based on the assumption of stationary environmental systems. In the context of gl ...
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 18

 TERMINÉ 
This ERC-StG 2014 proposal, SILION, outlines a strategy for the one-pot synthesis, characterization, and reactivity investigation of a positively charged, electron-deficient, highly Lewis acidic, cationic silicon(II) species, denoted “silyliumylidene ions”. Silyliumylidene ion has only four valence electrons, consisting of a lone pair of electrons and two vacant orbitals on the central silicon ato ...
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 2

 TERMINÉ 
The sentences: “I have written a proposal for the ERC” and “It is for the ERC that I have written a proposal” mean the same, but they have a different focus structure. A focused element like “It is for the ERC” indicates that alternatives are relevant for the interpretation of the utterance. Hence, the sentence expresses, in addition to its literal content, that the proposal is not for the NSF or ...
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 1

 TERMINÉ 
Intracellular aggregation of the human amyloid protein alpha-synuclein is causally involved in Parkinson’s disease, a debilitating neurodegenerative disorder. The goal of this project is to combine low-resolution, fluorescence-imaging methods with high-resolution in-cell NMR and EPR spectroscopy techniques to derive macroscopic and microscopic insights into alpha-synuclein aggregate structures dir ...
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 1

 TERMINÉ 
Alarming statistics in a recent report by the EU Agency for Fundamental Rights suggest that 1 in 3 women have experienced physical or sexual violence in childhood. The sequelae of childhood trauma (CT) exposure include psychopathology, altered stress physiology, obesity, and increased likelihood of exposure to violence in adulthood. Also, emerging evidence suggests the long shadow cast by CT may b ...
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 1

 TERMINÉ 
"We will use strain engineering as an enabling tool to study previously inaccessible or hard-to-study phenomena in two-dimensional atomic crystals (2DACs: graphene, bilayer graphene, and monolayer transition metal dichalcogenides). In our first objective, we develop unique experimental tools to control and characterize mechanical strain in 2DACs. These are the distinguishing features of our approa ...
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 1

 TERMINÉ 

Fishfriendly Innovative Technologies for Hydropower (FIThydro)

Date du début: 1 nov. 2016, Date de fin: 31 oct. 2020,

FIThydro addresses the decision support in commissioning and operating hydropower plants (HPP) by use of existing and innovative technologies. It concentrates on mitigation measures and strategies to develop cost-efficient environmental solutions and on strategies to avoid individual fish damage and enhancing population developments. Therefore HPPS all over Europe are involved as test sites. The f ...
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 26

 TERMINÉ 

IMMUNOBIOLOGY OF LYMPHOID STROMAL CELLS (STROMA)

Date du début: 1 oct. 2015, Date de fin: 30 sept. 2020,

In 1984, Nossal wrote ‘‘A readership consisting of primarily anatomists has every right to question the favorite sport of research workers in cell immunology. This is to take a lymphoid tissue and totally destroy its beautiful and elaborately designed architecture to obtain simple cell suspension of lymphocytes, which are then asked to do more or less all the jobs of the original anatomic masterpi ...
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 2

 TERMINÉ 
E-CAM will create, develop and sustain a European infrastructure for computational science applied to simulation and modelling of materials and of biological processes of industrial and societal importance. Building on the already significant network of 15 CECAM centres across Europe and the PRACE initiative, it will create a distributed, sustainable centre for simulation and modelling at and acro ...
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 18

 TERMINÉ 
P2Endure aims to provide scalable, adaptable and ready-to-implement prefabricated Plug-and-Play (PnP) systems for deep renovation of building envelopes and technical systems. These innovative solutions will be used to transform non-functioning or sub-optimal public and historic buildings into dwellings, and applicable for the widest range of building typologies, i.e. public buildings, residential ...
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 16

 TERMINÉ 
A large number of neurological and psychiatric disorders lack objective criteria for primary diagnoses, early differential diagnosis with regard to subtypes in treatment response and disease progression or effective therapy monitoring resulting in a tremendous negative socio-economic impact. Scientific studies based on advanced MRI methods indicate that related patients show specific subtle change ...
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 7

 TERMINÉ 
...e their potential. The academic organizations involved (University of Agriculture in Krakow PL, University of Copenhagen DK, University of Nottingham UK, University of Ghent BE, Technische University Berlin DE, and KU Leuven BE), will be supported by partners: VLB Berlin DE, FlavorActiV UK, Carlsberg Group DK and Boortmalt BE, to ensure well balanced research-business environment.
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 6

 TERMINÉ 
GLORIA aims to prove that the addition of chronic low dose glucocorticoids (GC) to current antirheumatic therapy is highly cost-effective and safe in elderly patients with rheumatoid arthritis (RA). RA is a frequent (affecting > 2% of the elderly population), painful and disabling chronic disease with high societal costs. RA is associated with multiple comorbidities, polypharmacy and adverse event ...
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 13

 TERMINÉ 

Multiscale modelling of stimuli-responsive nanoreactors (NANOREACTOR)

Date du début: 1 août 2015, Date de fin: 31 juil. 2020,

The catalysis by metal nanoparticles is one of the fastest growing areas in nanoscience due to our society's exploding need for fuels, drugs, and environmental remediation. However, the optimal control of catalytic activity and selectivity remains one of the grand challenges in the 21st century.Here, I propose to theoretically derive design rules for the optimization of nanoparticle catalysis by m ...
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 1