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25 projets européens trouvés

Recherche sur 125080 projets européens

 TERMINÉ 

Choices and consumption: modelling long and short term decisions in a changing world (DECISIONS)

Date du début: 1 juil. 2014, Date de fin: 30 juin 2019,

"Mathematical models of choice behaviour are used to understand consumer decisions and valuations and forecast choices across a range of topic areas, including transport and regional science. Their outputs form a key component in guidance underpinning government and industry decisions on changes to policy, infrastructure developments or the introduction of new services or products. Given the signi ...
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 1

 TERMINÉ 

Novel cancer vaccines with virus based cDNA libraries and monitoring for resistant tumour cell populations in prostate cancer (ONCOVIRVAX)

Date du début: 1 mars 2014, Date de fin: 28 févr. 2019,

"Prostate cancer is a huge burden of disease in Europe and the world and patients frequently relapse after initial attempts at the cure of localised disease. Cancer vaccination has activity but is only moderately effective. My ERC Advanced Award will use novel translational approaches to take a highly novel vaccine strategy which is excellent in mouse models towards a clinical vaccine for prost ...
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 1

 TERMINÉ 

"German Operetta in London and New York, 1907–1939: Cultural Transfer and Transformation" (GOLNY)

Date du début: 1 mars 2014, Date de fin: 28 févr. 2019,

"The term ""German operetta"" in the project title embraces twentieth-century operettas originating in both Austria and Germany. These enjoyed remarkable success in London and New York during 1907–1937, and, without deeper knowledge of them and their audience reception, we are sadly lacking in our understanding of the cultural mainstream in early twentieth-century Austria, Germany, the UK, and USA ...
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 1

 TERMINÉ 

Engineering Solutions for Back Pain: Simulation of Patient Variance (BACKTOBACK)

Date du début: 1 déc. 2012, Date de fin: 30 nov. 2018,

Back pain affects eight out of ten adults during their lifetime. It a huge economic burden on society, estimated to cost as much as 1-2% of gross national product in several European countries. Treatments for back pain have lower levels of success and are not as technologically mature as those for other musculoskeletal disorders such as hip and knee replacement. This application proposes to tackl ...
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 2

 TERMINÉ 

Tropical forests in the changing earth system (T-FORCES)

Date du début: 1 juil. 2012, Date de fin: 30 juin 2018,

The ambition of this proposal is to determine, from the ground up, the changing role of tropical forests in the global carbon cycle. The scientific objectives are: (1) Determine the trajectory of change in remaining tropical forests, (2) Unravel the drivers of change, (3) Gauge the sensitivity of forests to the climate change threat, and (4) Scale the findings to the present and future earth syste ...
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 2

 TERMINÉ 

Amyloid fibril cytotoxicity: new insights from novel approaches (AMYTOX)

Date du début: 1 mai 2013, Date de fin: 30 avr. 2018,

"Despite the discovery of amyloidosis more than a century ago, the molecular and cellular mechanisms of these devastating human disorders remain obscure. In addition to their involvement in disease, amyloid fibrils perform physiological functions, whilst others have potentials as biomaterials. To realise their use in nanotechnology and to enable the development of amyloid therapies, there is an ur ...
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 1

 TERMINÉ 

What is the mechanism of the true chronic effect of dietary polyphenols? (POLYTRUE?)

Date du début: 1 avr. 2013, Date de fin: 31 mars 2018,

"Although there have been many epidemiological and intervention studies on polyphenol-rich foods showing promising effects in reducing the risk of heart disease and diabetes, the true mechanisms of action remain elusive. In vitro systems to study nutritional mechanisms are limited by several factors and most have been derived from acute studies relevant to pharmaceutical research. In order to dete ...
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 1

 TERMINÉ 

The calm before the storm: Pre-stellar cores as Astrophysical Laboratories (PALs)

Date du début: 1 mars 2013, Date de fin: 28 févr. 2018,

"Stars like our Sun and planets like our Earth form in dense regions within interstellar molecular clouds, called pre-stellar cores (PSCs). PSCs provide the initial conditions in the process of star and planet formation, but large uncertainties exist concerning basic astrophysical processes and parameters, such as surface chemistry, the cosmic-ray ionization rate, the H2 ortho-to-para ratio, the ...
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 5

 TERMINÉ 

Investigating the therapeutic potential of manipulating the IGF-IGFBP1 axis in the prevention and treatment of cardiovascular disease, diabetes and obesity (BP-CarDiO)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,

More than 30 million people are living with diabetes in the EU, with a prevalence expected to grow to over 10% of the adult population by the year 2030. Type 2 diabetes is a major cause of cardiovascular disease related death and disability, substantially increasing the risk of myocardial infarction, stroke and peripheral arterial disease. Recent landmark trials, showing that intensive glucose con ...
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 1

 TERMINÉ 

The nature of representation (NatRep)

Date du début: 1 nov. 2012, Date de fin: 31 oct. 2017,

This project aims to transform our understanding of mental and linguistic representation, its nature and significance for explanatory projects inside and outside philosophy. It seeks to show that the contemporary trend towards “deflationary” and non-explanatory treatments of representation is misguided, and that a naturalistic treatment of representation is available. By bringing together contempo ...
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 1

 TERMINÉ 

Advancing Knowledge Systems to Inform Climate Adaptation Decisions (ICAD)

Date du début: 1 avr. 2012, Date de fin: 31 mars 2017,

Adaptation to climate variability and change represents an important challenge for the sustainable development of society. Informing climate-related decisions will require new kinds of information and new ways of thinking and learning to function effectively in a changing climate. Adaptation research requires integration across disciplines and across research methodologies. Currently, we lack the ...
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 1

 TERMINÉ 

Cosmic Dust in the Terrestrial Atmosphere (CODITA)

Date du début: 1 avr. 2012, Date de fin: 31 mars 2017,

"This project addresses a fundamental problem – the size of the cosmic dust input to the earth’s atmosphere. Zodiacal cloud observations and spaceborne dust detection indicate a daily input of 100 – 300 tonnes, in agreement with the accumulation rates of cosmic elements (e.g. Ir, Pt) in polar ice cores and deep-sea sediments. In contrast, measurements in the middle atmosphere – by radar, lidar, hi ...
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 1

 TERMINÉ 

Membrane-modified Electrodes to study Membrane Enzymes (MEME)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2016,

"Electrochemical investigations of biological processes have provided a wealth of information on the structure-function relationship of redox enzymes, while the underlying technology has formed the basis for biosensors such as the extremely successful glucose biosensor. However, many of today’s applications do not impose molecular control on the electrode-protein interaction, which limits their fu ...
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 1

 TERMINÉ 

The Effects of Marketization on Societies: The Case of Europe (TEMS)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

"In the European Union and beyond, policymakers have come to use the market as a general-purpose policy tool. Dissatisfied with the existing institutions of capitalism, they have introduced price-based competition into new areas of life and ratcheted up competition where markets were already present. Although the recent financial crises have sparked protests and fuelled criticisms of the capitalis ...
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 2

 TERMINÉ 

Pliocene Constraints on Earth System Sensitivity (Plio-ESS)

Date du début: 1 déc. 2011, Date de fin: 30 nov. 2016,

The magnitude of long-term global temperature rise due to an increasing concentration of carbon dioxide (CO2) in the atmosphere is a question of relevance to policy makers and society. Previous studies have addressed this issue on the basis of the equilibrium response of the climate system due to fast feedbacks such as clouds and sea ice-albedo, often referred to as Climate Sensitivity. Plio-ESS w ...
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 1

 TERMINÉ 

Extreme biophysics: single molecule characterisation of extremophilic protein folding (EXTREME BIOPHYSICS)

Date du début: 1 janv. 2011, Date de fin: 30 sept. 2016,

"Extremophilic (extreme-loving) organisms have evolved unique features to enable them to function in extreme environmental conditions. Despite much progress in understanding extremophilic protein structure, there is a lack of quantitative information on the conformational dynamics and flexibility of proteins in extreme environments, information which is crucial to develop an understanding of their ...
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 1

 TERMINÉ 

Pre-receptor cortisol metabolism and human ageing (PRECORT)

Date du début: 1 mai 2010, Date de fin: 30 avr. 2016,

"The number of people over the age of 80 years in the 25 EU member states is currently 18.2 million or 4% of the total population; by 2020, 20% of the EU population will be >65 years old which will place considerable burden upon limited health care resources. 70% of older adults report at least one chronic disease that contributes to a reduction in healthspan or the number of extra years spent ...
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 2

 TERMINÉ 

Re engineering and regenerating the knee (regenknee)

Date du début: 1 avr. 2011, Date de fin: 31 mars 2016,

Over fifteen percent of the western population suffer from osteoarthritis. For severe disability, total joint replacement remains the onlty treatment. The ageing population is growing and their expectations for an active, high quality lifestyle is increasing. The number of knee joint replacements is predicted to increase five time by 2025. While technology for knee joint replacements has advanced ...
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 1

 TERMINÉ 

Oral culture, manuscript and print in early modern Italy, 1450-1700 (ItalianVoices)

Date du début: 1 juin 2011, Date de fin: 30 nov. 2015,

From the palazzo to the piazza, from the church to the private household, the spoken and sung word had uniquely important roles to play in transmitting information, opinions and texts in the society of early modern Italy. Oral discussion and performance, both formal and informal, were used intensively in the culture of the literate minority, while the verbal culture of the uneducated depended main ...
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 1

 TERMINÉ 

Development of Proteomimetics as Drug Discovery Screening Tools (PROTEOSCREEN)

Date du début: 1 août 2014, Date de fin: 31 juil. 2015,

The objective of ProteoScreen is to demonstrate Proof of Concept that proteomimetics can be exploited as (a) a surfacebased screening platform and (b) a tool for in cellulo target ID. In doing so I will demonstrate commercial use of theProteomimetic technology developed in the ERC ProteoFold project.
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 1

 TERMINÉ 

Laboratory and modelling studies of ice nucleation and crystallisation in the Earth's atmosphere (ICE)

Date du début: 1 nov. 2009, Date de fin: 30 avr. 2015,

The formation of ice particles in the Earth s atmosphere strongly affects the properties of clouds and their impact on climate. However, our basic understanding of ice nucleation and crystallisation is still in its infancy. Despite the importance of ice formation in determining the properties of clouds, the Intergovernmental Panel on Climate Change (IPCC) was unable to assess the impact of atmosph ...
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 1

 TERMINÉ 

Terahertz Optoelectronics - from the Science of Cascades to Applications (TOSCA)

Date du début: 1 avr. 2010, Date de fin: 31 mars 2015,

Over the last 10 years, research in the terahertz (THz) frequency region of the electromagnetic spectrum has grown dramatically. The most significant development has been the demonstration of the first THz frequency quantum cascade laser (QCL) in 2002 by my EC FP-V consortium, WANTED. These advances have been accompanied by an equally important industrial applications-pull, with exploitation envis ...
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 1

 TERMINÉ 

Proteomimetic Foldamers: Towards Future Therapeutics and Designer Enzymes (PROTEOFOLD)

Date du début: 1 févr. 2010, Date de fin: 31 janv. 2015,

The purpose of this project is to develop a RULE-BASED APPROACH for the design and synthesis of proteomimetics of the alpha-helix and in doing so establish to what extent the structural and functional role of the alpha-helix can be reproduced with non-natural molecules in a PREDICTABLE manner We will focus on developing aromatic oligoamide proteomimetics (compounds that mimic the secondary structu ...
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 1

 TERMINÉ 

Video Communications for Networked Communities (Vconect)

Date du début: 1 déc. 2011, Date de fin: 30 nov. 2014,

The inability to discover the conversations that matter, to understand how others are feeling, to recognise a friend in need, to share the joy of someone happy, or to see how certain things should be done, are common limitations of social networks. All these require people to be able to see and hear each other. Vconect targets this space by aiming to develop capabilities that will allow ad-hoc gro ...
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 9

 TERMINÉ 

Ethics in Public Policy Making: The Case of Human Enhancement (EPOCH)

Date du début: 1 nov. 2010, Date de fin: 31 oct. 2012,

EPOCH aims both to broaden and deepen knowledge of the role of ethics in the governance of science and technology, focusing on ethical aspects of new and emerging bio-, neuro- and nanotechnologies and specifically related to the topic of human enhancement (i.e. any modification of the human body aimed at improving performance and realized by scientific-technological means). On the basis of compara ...
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 10