9 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Integrative Analysis of Gene Functions in Cellular and Animal Models of Pancreatic Cancer (CAM-PAC)
Date du début: 1 nov. 2013, Date de fin: 31 oct. 2018,
Cancers are genetic disease arising from the accumulation of multiple molecular alterations in affected cells. Large-scale genomic, transcriptomic and proteomic analyses have established comprehensive catalogues of molecules which are altered in their structure and/or abundance in malignant tumors as compared to healthy tissues. Far less developed are concepts and methods to integrate data from di ...
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18
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TERMINÉ
Regulation and Function of CARD9 / BCL10 / MALT1 Signalosomes in Innate Immunity and Inflammation (CBM-Innate)
Date du début: 1 févr. 2013, Date de fin: 31 janv. 2018,
Acute inflammation is a response to infection or tissue damage that is critical for host protection and tissue homeostasis. However, deregulated or chronic inflammation is harmful to the host and can cause multiple diseases including inflammatory bowel disease, rheumatoid arthritis, cardiovascular diseases, neuroinflammatory disease and cancer. Cells of the innate immune system sense microbial or ...
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1
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TERMINÉ
Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter Defibrillators in EUrope (EU-CERT-ICD)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,
An estimated 500.000 sudden cardiac deaths (SCD) occur each year in the European Union. Patients at risk for SCD may benefit from prophylactic treatment with an implantable cardioverter-defibrillator (ICD). ICD implantations have dramatically increased in recent years leading to multi-billion Euros of costs with significant regional disparities across Europe. Information on risks, benefits and cos ...
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27
Participants partenaires
TERMINÉ
Modeling congenital heart disease (CHD) in ISL1+ cardiovascular progenitors from patient-specific iPS cells (CHD-iPS)
Date du début: 1 mars 2011, Date de fin: 28 févr. 2017,
Tetralogy of Fallot (TOF) is the most common congenital heart disease (CHD) occurring 1 in 3000 births. Genetic studies have identified numerous genes that are responsible for inherited and sporadic forms of TOF, most of which encode key molecules that are part of regulatory networks controlling heart development. The identification of two populations of cardiac precursors, one exclusively forming ...
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1
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TERMINÉ
Mitochondrial European Educational Training (MEET)
Date du début: 14 janv. 2013, Date de fin: 13 janv. 2017,
"The expanding diversification and specialization of knowledge and the growing complexity of contemporary research in translational research warrant the creation of cooperative multi-disciplinary networks including both basic and medically oriented expertise. This notion is especially true for Mitochondrial Medicine which aims at understanding the physiopathological mechanisms sharing the features ...
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10
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TERMINÉ
Improving HSCT By Validation Of Biomarkers & Development Of Novel Cellular Therapies (CELLEUROPE)
Date du début: 1 oct. 2012, Date de fin: 30 sept. 2016,
Novel transplant regimens are currently being developed to improve beneficial GvL effects and reduce GvHD and infections via several new forms of cellular therapies. This newly emerging supra-disciplinary field of cellular therapy and regenerative medicine is also being used to improve outcomes in autoimmune disease (such as Rheumatoid Arthritis) and cancers. The goal of this research programme is ...
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13
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TERMINÉ
Future Internet Social and Technological Alignment Research (FI-STAR)
Date du début: 1 avr. 2013, Date de fin: 30 sept. 2015,
FI-STAR will establish early trials in the Health Care domain building on Future Internet (FI) technology leveraging on the outcomes of FI-PPP Phase 1. It will become self-sufficient after the end of the project and will continue on a sustainable business model by several partners. In order to meet the requirements of a global Health industry FI-STAR will use a fundamentally different, "reverse" c ...
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44
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TERMINÉ
Towards an Embodied Science of InterSubjectivity (TESIS)
Date du début: 1 mars 2011, Date de fin: 28 févr. 2015,
TESIS, “Towards an Embodied Science of InterSubjectivity”, is an integrated ITN programme to investigate the foundations of human sociality. It brings together the complementary expertise of 13 European research institutes, clinical centres and private enterprises that span the biomedical sciences and the humanities. Thus, TESIS provides critical mass in the fields of philosophy, cognitive neurosc ...
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8
Participants partenaires
TERMINÉ
Targeting the tumour microenvironment to improve pancreatic cancer prognosis (EPC-TM-Net)
Date du début: 1 févr. 2011, Date de fin: 31 juil. 2014,
Pancreatic cancer is one of the most lethal human cancers with a five-year survival rate of less than 5%. Late presentation and a high level of resistance to chemotherapeutic drugs are among the major reasons for this dismal prognosis. The presence of the highest degree of desmoplasia among all solid tumours and the fact that chronic inflammatory pancreatic disease is associated with an increased ...
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