11 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
A drug strategy targeting stabilised mutant p53 to fight metastatic platinum-resistant ovarian cancer (GANNET53)
Date du début: 1 oct. 2013, Date de fin: 31 mars 2019,
"Epithelial ovarian cancer (EOC) is the most lethal gyncaecological malignancy causing 41900 deaths annually in Europe. The predominance of aggressive Type II tumours, which are characterised by a high frequency of p53 mutations, and primary or acquired resistance to platinum-based chemotherapy profoundly contribute to the high mortality rate. With current standard therapy the median overall survi ...
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20
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TERMINÉ
"Comparing policy framework, structure, effectiveness and cost-effectiveness of functional and integrated systems of mental health care" (COFI)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,
"Mental disorders affect 38.2% of the EU population. For reducing the associated burden, countries across Europe engage in costly re-organizations of mental health care systems. Reforms focus on one controversial core question: Should systems be functional or integrated? In functional systems, separate staff in different services are in charge of in- and out-patient care (to enhance specialization ...
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7
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TERMINÉ
Early Prevention of Diabetes Complications in people with Hyperglycaemia in Europe (E-PREDICE)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2017,
"Background: A significant proportion of pre-diabetics, show macro and micro vascular complications associated with hyperglycaemia. Although many trials have demonstrated the efficacy of lifestyle and pharmaceutical interventions in diabetes prevention, no trial has evaluated the extent to which mid- and long-term complications can be prevented by early interventions on hyperglycaemia.Aims: To ass ...
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37
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TERMINÉ
Disarming the intravascular innate immune response to improve treatment modalities for chronic kidney disease (DIREKT)
Date du début: 1 déc. 2013, Date de fin: 30 nov. 2017,
"Chronic kidney disease is world wide a major cause of end-stage renal disease (ESRD). 800.000 patients in Europe and in the US, respectively, require long-term treatment initially with peritoneal dialysis, followed by hemodialysis and kidney transplantation. Each ESRD patient on hemodialysis costs ≈€40000 to €80000 per year, has extremely poor quality of life and an average life expectancy of onl ...
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12
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TERMINÉ
Tumor Infiltrating Myeloid Cell Compartment (TIMCC)
Date du début: 1 nov. 2012, Date de fin: 31 oct. 2016,
"The ITN TIMCC brings together eight expert teams from different disciplines within Immunology, Genetics and Oncology, to provide substantive and methodological training in the analysis of the role of the Tumor Infiltrating Myeloid Cell Compartment (TIMCC) of the innate immune system. Leukocytes recruited to (pre)malignant tissues are mainly myeloid cells. They can either prevent or functionally c ...
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8
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TERMINÉ
Technology Transfer in Computing Systems (TETRACOM)
Date du début: 1 sept. 2013, Date de fin: 31 août 2016,
The mission of the TETRACOM Coordination Action is to boost European academia-to-industry technology transfer (TT) in all domains of Computing Systems. While many other European and national initiatives focus on training of entrepreneurs and support for start-up companies, the key differentiator of TETRACOM is a novel instrument called Technology Transfer Project (TTP). TTPs help to lower the barr ...
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33
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TERMINÉ
Genomic and lifestyle predictors of foetal outcome relevant to diabetes and obesity and their relevance to prevention strategies in South Asian peoples (GIFTS)
Date du début: 1 févr. 2012, Date de fin: 31 janv. 2016,
Despite a strong genetic component to diabetes and obesity, the rapidly rising prevalence of these disorders is due to adaptation to a changing environment. The epicentre of the ‘diabetes epidemic’ is in South Asia and this is reflected in the migrant populations in Europe. Current prevention strategies are focused on adult life and target over-nutrition in high-risk adults. However, for many popu ...
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16
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TERMINÉ
Enhancing the (cost-)effectiveness of diabetes self-management education: A comparative assessment of different educational approaches and conditions for successful implementation (DIABETES LITERACY)
Date du début: 1 nov. 2012, Date de fin: 31 déc. 2015,
The project aims to contribute to building the evidence base to increase the effectiveness of diabetes self-management education in the EU Member States, as part of a comprehensive diabetes strategy at EU level. To that effect, it will perform a systematic and comparative content analysis of the national diabetes strategies and frameworks across the 27 EU MS, establish a compendium of diabetes sel ...
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9
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TERMINÉ
The European Network for Translational Research in Atrial Fibrillation (EUTRAF)
Date du début: 1 nov. 2010, Date de fin: 31 oct. 2015,
"The initiation and perpetuation of atrial fibrillation (AF) can be regarded as a complication of a progressive transformation of the structure and functional properties of the atria. This transformation is the result of complex and multiple changes at the molecular, cellular and organ levels which interact to form the basis for proarrhythmic mechanisms in AF. Numerous individual and environmental ...
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20
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TERMINÉ
Application of the innovative data fusion based non-invasive approach for management of the diabetes mellitus (SKINDETECTOR)
Date du début: 1 nov. 2012, Date de fin: 31 oct. 2014,
Diabetes mellitus (DM) is a heterogeneous group of disorders characterized by a high serum glucose level and by disturbances of carbohydrate and lipid metabolism.Diabetics had a greater prevalence of skin manifestations in type 2 than type 1, and as the duration of the DM increased, the likelihood of developing skin manifestations also increased.Early referral to the dermatologist may help to dete ...
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10
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TERMINÉ
Characterisation of molecules regulating adult hippocampal neurogenesis (MolRegNeurogen)
Date du début: 1 avr. 2011, Date de fin: 31 mars 2013,
The hippocampus contains a population of stem cells that continually proliferate to produce new neurons. The development of new markers capable of identifying and isolating defined neural stem cell populations are of utmost importance. Prominin-1 has successfully been used as a marker for the isolation of neural stem and progenitor cells from other brain regions including the mouse embryonic foreb ...
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