2 projets européens trouvés
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TERMINÉ
Development of solid state NMR methods at 100 kHz magic angle spinning frequency for the study of internal protein dynamics and the application to membrane proteins (SOLID_NMR_DYNAMICS)
Date du début: 1 juin 2014, Date de fin: 31 mai 2016,
This proposal concerns the development of new solid-state NMR methods using proton detection under Magic Angle Spinning (MAS) with frequencies up to 100 kHz. The 100 kHz MAS probe head is a prototype and will allow significant gains in sensitivity by scaling down the 1H-1H dipolar coupling interaction and resulting in narrow proton line width down to 10-20 Hz. Small quantities of protein samples i ...
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TERMINÉ
NMR for Structural Biology (Bio-NMR)
Date du début: 1 sept. 2010, Date de fin: 31 août 2014,
In the past two decades spectacular insight into basic principles of life has been obtained from paradigmatic high-resolution structural investigations providing a rational basis for biological experiments. NMR is an indispensable enabling technology for determining such structures and their interactions in solution, the immobilized state and living cells. The power of NMR to link structural, dyna ...
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