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9 projets européens trouvés

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 TERMINÉ 
Despite a great progress in the management of epilepsy, still one third of patients is refractory to available medications. The incidence of epilepsy is highest in infancy and 50% of children experience epilepsy-related comorbidities, such as developmental delay and autism. The development of epilepsy (epileptogenesis), extensively studied in animals, is barely studied in humans, as patients usual ...
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 16

 TERMINÉ 

Systems Biology to Identify Molecular Targets for Vascular Disease Treatment (SYSVASC)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,

Asymptomatic vascular damage accumulates for years before patients are identified and subjected to therapeutic measures. The limited knowledge on early vascular disease pathophysiology is reflected in the lack of therapeutic options. SysVasc aims to overcome this limitation by mounting a comprehensive systems medicine approach to elucidate pathological mechanisms, which will yield molecular target ...
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 19

 TERMINÉ 

Long-term effects of early nutrition on later health (EARLYNUTRITION)

Date du début: 1 févr. 2012, Date de fin: 31 oct. 2017,

Nutrition during early development has an important impact on later health, particularly through greater obesity risk, as demonstrated by FP6 EARNEST. EarlyNutrition explores the current key hypotheses on likely causes and pathways to prevention of early life origins of obesity (specifically adiposity) and associated disorders. We bring extraordinary expertise and study populations of 470,000 indi ...
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 40

 TERMINÉ 

Translational research (training) in Polycystic Kidney Disease (TranCYST)

Date du début: 1 déc. 2012, Date de fin: 30 nov. 2016,

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is an inherited kidney disorder with a prevalence of more than 1:1000, characterized by the development of renal cysts, slowly progressing towards end-stage renal disease. ADPKD is often associated with extra-renal complications, which can be devastating. Current therapy is directed towards limiting the morbidity and mortality from these complic ...
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 7

 TERMINÉ 

Integrated research on DEvelopmental determinants of Aging and Longevity (IDEAL)

Date du début: 1 févr. 2011, Date de fin: 31 janv. 2016,

"IDEAL will obtain insight into the role of early life conditions affecting late-life health, disease and aging, and the role of epigenetic regulation therein. IDEAL will identify the determinants and targets of this epigenetic regulation utilizing a resource of unique human cohorts and animal studies that allow testing of hypotheses on the link between development and aging.Key objectives of IDEA ...
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 16

 TERMINÉ 
As the trend to open up data and provide them freely on the Internet intensifies, the opportunities to create added value by combining and cross-indexing heterogeneous data at a large scale increase. To seize them, we need infrastructure that is not only efficient, real-time responsive and scalable but is also flexible and robust enough to welcome data in any schema and form and to transparently r ...
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 8

 TERMINÉ 

Innovation Framework for Privacy and Cyber Security Market Opportunities (IPaCSO)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2015,

Innovation drives new product realisation and development. Significant opportunities exist for innovation in the privacy and cyber security (PACS) technology space, yet complex market, regulatory, policy, commercial, and economic considerations create several barriers to transforming research outputs into market-centric product and service applications. In response, Innovation Framework for Privac ...
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 5

 TERMINÉ 
The goal of agrobiodiversity conservation, unlike other forms of conservation, is not only the conservation of species and intra-specific genetic diversity related to agriculture, but also to promote its sustainable use in facilitating agricultural production. Although significant progress has been made in the conservation and management of plant genetic resources for food and agriculture (PGRFA) ...
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 11

 TERMINÉ 
Bioresistancy of building and finishing materials usually requires addition of dedicated bioactive chemicals, so-called biocides. The usual increase in biocide concentration only results in a minor prolongation of the material service-life. For example, coatings usually exhibit biocidal functionality between 0.5 and 2 years – depending on environmental loads –, whereas the desired service life in ...
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 10