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Molecular tattooing: azidated compounds pave the path towards light-activated covalent inhibitors for drug development (AZIDRUGS)
Date du début: 1 déc. 2013, Date de fin: 30 nov. 2014,
Until now the greatest limitation in the application of bioactive compounds has been the inability of confining them specifically to single cells or subcellular components within the organism. Our recently synthesized photoactive forms of bioactive compounds solve this problem. We have developed effective chemical synthesis methods to attach an azide group to small drug-like molecules, which makes ...
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