3 projets européens trouvés
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TERMINÉ
"Design and development of novel reagents, tools, and techniques targeting human glutamate carboxypeptidases II and III" (GCPII_SYSTEM)
Date du début: 1 nov. 2010, Date de fin: 31 oct. 2014,
"Glutamate carboxypeptidase II (GCPII) is a membrane-bound metallopeptidase with a vast pharmacological potential. Given the intimate involvement of the enzyme in neurotransmission under normal physiological conditions, it is not surprising that GCPII-specific inhibitors are neuroprotective in multiple preclinical models of neurodegeneration. Additionally, the cancer-associated form of GCPII is ex ...
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1
Participant partenaire
TERMINÉ
Standardisation and improvement of generic pre-analytical tools and procedures for in vitro diagnostics (SPIDIA)
Date du début: 1 oct. 2008, Date de fin: 31 mars 2013,
"In vitro diagnostics have allowed a great deal of progress in medicine but are limited by two factors: (a) the lack of guidelines in collection, handling, stabilisation and storage of biosamples which limits the reproducibility of subsequent diagnoses, and (b) its scale is restrained to the cellular level. To address this first point, this IP, SPIDIA, built of clinicians, academics, tool and assa ...
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17
Participants partenaires
TERMINÉ
Molecular Mechanisms in Diabetic Embryopathy (Diabetic Embryopathy)
Date du début: 1 sept. 2008, Date de fin: 31 août 2012,
The main objectives of the proposed reintegration research grant are: 1) to investigate the molecular causes of diabetic embryopathy; 2) to transfer my knowledge and experience to the Czech and European academia and industry; and 3) to develop a network of future international research collaboration dealing with diabetes. The scientific objective is to understand how maternal diabetes affects the ...
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