5 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Nanomedicine upscaling for early clinical phases of multimodal cancer therapy (NoCanTher)
Date du début: 1 avr. 2016, Date de fin: 31 mars 2021,
During the last four years the Multifun Consortium (FP7 project Nº. 262943) has developed and validated distinct nanoformulations as therapeutic approach against pancreatic and breast cancer. These nanoformulations are based on magnetic iron oxide nanoparticles (MNP) multifuntionalised with a target peptide and an anticancer chemical drug, allowing for a synergistic therapeutic effect produced by ...
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13
Participants partenaires
TERMINÉ
Smart multifunctional GLA-nanoformulation for Fabry disease (Smart-4-Fabry)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
Lysosomal storage disorders (LSD) diseases are a group of rare diseases that currently lack a definitive cure. LSD incidence is about 1:5,000 - 1:10,000, representing a serious global health problem. In the case of Fabry LSD Disease (FD), the deficiency in α-Galactosidase A (GLA) enzyme activity results in the cellular accumulation of neutral glycosphingolipids, leading to widespread vasculopathy ...
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10
Participants partenaires
TERMINÉ
Novel therapeutic approaches for the treatment of cystic fibrosis based on small molecule transmembrane anion transporters (TAT-CF)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2018,
This project will develop an innovative therapeutic approach for the treatment of Cystic Fibrosis (CF). This condition originates from the defective function of the CFTR protein, a chloride and bicarbonate permeable transmembrane channel. This project will evaluate small molecules capable of facilitating the transmembrane transport of anions such as chloride and bicarbonate and will thus enable CF ...
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8
Participants partenaires
TERMINÉ
Microbubble driven multimodal imaging and theranostics for gliomas (THERAGLIO)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2018,
Microbubbles (MBs) are used as contrast agent in ultrasound (US) imaging for a variety of tumours while little has been done for glioblastomas, a rare cancer. Intraoperative Contrast-Enhanced US-imaging (CEUS) using lipidic MBs hold promises in increasing extent of resection of such tumors. Furthermore, MBs gained recently interest as a delivery system for drugs. We will develop a new generation o ...
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12
Participants partenaires
TERMINÉ
Benznidazol and Triazol REsearch group for Nanomedicine and Innovation on Chagas diseasE (BERENICE)
Date du début: 1 sept. 2012, Date de fin: 31 août 2017,
The BERENICE consortium is aiming at providing a new and cost-effective solution to a better treatment for Chagas chronic patients. Please see its objectives below :Main objective• Obtain a more effective, better tolerated and cheaper formulation of a drug with trypanocidal activity to cure Chagas diseaseSpecific Objectives• Obtain results of pharmacokinetics of new formulations• Assess trypanocid ...
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