3 projets européens trouvés
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TERMINÉ
The role of non coding RNA in human health and disease (RNA_REGULOMICS)
Date du début: 1 oct. 2012, Date de fin: 30 sept. 2016,
"RNA molecules have been already proven to be a key target for disease therapy as well as a tool for the development of new drugs. Since the discovery of small non coding RNA (ncRNA) and all the associated phenomena like RNA interference, the possibility of using RNA-based drugs has become a subject of great interest in the pharmaceutical and clinical fields. ncRNA is at the core of many cellular ...
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3
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TERMINÉ
Identification and characterization of molecular markers of pancreatic Endocrine Progenitor Cells (Pancreatic Stem Cell)
Date du début: 1 avr. 2009, Date de fin: 31 mars 2013,
Embryonic stem (ES) cells are derived from the inner cell mass (ICM) of blastocyst-embryo stage. The potential of ES cells to differentiate in all kind of tissues, opens the possibility for future promising approaches, as genetic therapy and/or cell replacement, to treat many diseases, including type1 diabetes. Although several scientific groups have reported the successful differentiation of mous ...
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1
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TERMINÉ
Molecular characterization of cartilage development in the cephalopod mollusk Sepia officinalis (SepiaCartilage)
Date du début: 1 oct. 2009, Date de fin: 3 mars 2013,
The presence of cellular cartilage-like tissues outside the chordate lineage is either indicative of a common origin of cartilage as a metazoan tissue type (homology), or alternatively highlights developmental and/or structural constraints in constructing an internal cellular support tissue or endoskeleton (convergence). If a genetic program for specifying chondrocytes (cartilage cells) arose only ...
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