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Role of PGC 1ß co-activator in the brain: energy homeostasis, obesity, ageing and neuronal death (PGC1SS IN BRAIN)
Date du début: 11 sept. 2007, Date de fin: 10 sept. 2009,
Food intake and energy expenditure are the main components of energy balance and both are regulated by the central nervous system (CNS). Failure of these homeostatic mechanisms results in deregulation of lipid and glucose metabolism leading to insulin resistance and obesity.Defects in energy homeostasis may impact neuronal survival and accelerate the neurodegenerative process associated with agein ...
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