4 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Infectious triggers of chronic autoimmunity (INTRICATE)
Date du début: 1 nov. 2010, Date de fin: 30 avr. 2015,
This proposal builds on existing expertise and collaborations of a multidisciplinary Consortium of basic scientists and clinical investigators each of whom has made a substantial individual contribution to understanding the links between infection and autoimmunity. The aim of the INTRICATE Consortium is to prosecute a programme of Translational Research that deliniates the role of infection in the ...
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13
Participants partenaires
TERMINÉ
Genetic analysis of a novel family of repulsive guidance cues acting through Unc5 receptors (FLRT in neurobiology)
Date du début: 1 juin 2012, Date de fin: 31 mai 2014,
One of the most challenging problems in neurobiology is to understand the mechanisms that mediate the formation of a functional neuronal network. Despite the identification of several molecules that regulate axon guidance and cell migration, it is unclear how these factors can specify a large number of connections in the nervous system.The present project aims to study the role and mechanism of ac ...
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1
Participant partenaire
TERMINÉ
Imaging function and dysfunction of neuronal circuits in the visual cortex (EuroV1sion)
Date du début: 1 déc. 2008, Date de fin: 31 mai 2013,
The research program aims to understand the dynamics of the structural and functional organization of the visual cortex and the implications for amblyopia ('lazy eye', the most prevalent visual disorder among young people). We will study these fundamental issues from the molecular level all the way to the network level. To achieve this, members of the consortium have - for the first time - establi ...
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8
Participants partenaires
TERMINÉ
Visualizing the structural synaptic memory trace: presynaptic partners of newly formed spines (HebbianNewSpines)
Date du début: 1 avr. 2011, Date de fin: 31 mars 2013,
The formation and elimination of spine synapses can be visualized both in vitro as well as in vivo using advanced imaging techniques. It is known that the number of dendritic spines changes both during development as well as during the acquisition of new memories. However, up to now these observations are entirely correlative. It is unclear if the presynaptic neuron forming a functional contact on ...
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