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Plus de 40 projets européens trouvés

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 TERMINÉ 

iABC Programme (IABC PROGRAMME)

Date du début: 1 août 2015, Date de fin: 31 juil. 2020,

Cystic Fibrosis (CF) is a common fatal inherited disease with a frequency of 1 in 2500 live births, affecting approximately 36,000 (0.737/10,000) people in the EU. Chronic bacterial pulmonary infection leading to an irreversible decline in lung structure and function is the main cause of mortality and morbidity in patients with CF, with more than 95% of deaths due to respiratory failure. Pseudomon ...
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 21

 TERMINÉ 

Roads and the politics of thought: Ethnographic approaches to infrastructure development in South Asia (Roads)

Date du début: 1 févr. 2015, Date de fin: 31 janv. 2020,

New roads are being constructed at unprecedented rates in certain parts of the world. The proposed research will ask: Why? To what end? Who benefits? What ideas lie in the foundations of this new infrastructure? Roads are presented as solutions to poverty, ‘development’ and economic growth? Are they? In what ways? What else might roads do? As cheap oil dwindles and questions of climate change rema ...
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 3

 TERMINÉ 

Translating neuroimaging findings from research into clinical practice (PSYSCAN)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2020,

Abstract 9Neuroimaging (NI) has enormous potential to improve the clinical care of patients with psychiatric disorders, but has yet to deliver. The PSYSCAN project will address this issue directly by developing a NI-based tool that will help clinicians resolve key clinical issues in the management of patients with psychotic disorders. Clinicians will use the tool to assess patients with a standard ...
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 24

 TERMINÉ 

European Prevention of Alzheimer’s Dementia Consortium (EPAD)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2019,

Background:The secondary prevention of Alzheimer’s dementia (AD) is achievable if we can identify individuals at risk of disease progression defined by biomarker evidence of AD pathology and no or only minimal clinical symptoms and engage them in a standing adaptive clinical trial, of the highest quality, testing multiple interventions. To achieve this, EPAD will also provide the analytical infras ...
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 40

 TERMINÉ 

Adverse Immune Signatures and their Prevention in Corneal Transplantation (VISICORT)

Date du début: 1 avr. 2014, Date de fin: 31 mars 2019,

"Immune system response is the most complex barrier to long-term success of tissue transplants/implants from allogeneic and bio-artificial sources. While newly developed tissue transplant procedures are not yet performed frequently enough for robust analysis of adverse immune responses in humans, corneal transplantation (CT) is a well-established allogeneic tissue transplant with >100,000 full- an ...
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 12

 TERMINÉ 

Algorithms and Lower Bounds: A Unified Approach (ALUNIF)

Date du début: 1 mars 2014, Date de fin: 28 févr. 2019,

One of the fundamental goals of theoretical computer science is tounderstand the possibilities and limits of efficient computation. Thisquest has two dimensions. Thetheory of algorithms focuses on finding efficient solutions toproblems, while computational complexity theory aims to understand whenand why problems are hard to solve. These two areas have differentphilosophies and use different sets ...
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 2

 TERMINÉ 

Treatment of late onset bacterial sepsis caused by vancomycin susceptible bacteria in neonates and infants aged under three months (NEOVANC)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,

Vancomycin is the critically important antibiotic to treat neonatal Late Onset Sepsis (LOS) due to Gram positive bacteria in neonates, including Coagulase Negative Staphylococci (CoNS) and Staphylococcus aureus. These organisms also create biofilms which are extremely resistant to antibiotics. The increased incidence of LOS due to bacteria such as CoNS and MRSA in NICUs has led to a marked increas ...
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 14

 TERMINÉ 

Improving European aquaculture by advancing selective breeding to the next level for the six main finfish species (FISHBOOST)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,

Only about 10% of today’s global aquaculture production use genetically improved stocks. In Europe, some breeding programmes consist of only the basic components of a breeding scheme. Hence, there is large potential to increase efficiency and profit by domestication and genetic improvement of farmed finfish. The main challenge of FISHBOOST is to realise this potential into economic and social acce ...
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 27

 TERMINÉ 

The Neurobiology of Decision-Making in Eating - Innovative Tools (NUDGE-IT)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2018,

Nudge-it engages internationally leading experts in the neurobiology of motivational behaviour, the neuroscience of reward pathways, the neuroendocrinology of homeostatic regulation of appetite, experimental psychology, functional brain imaging, behavioural economics, and computational modelling. They will work together to develop new tools and approaches that can provide the evidence needed to in ...
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 10

 TERMINÉ 

CommerciaL Energy ARray for Widespread Acceleration of Tidal European Resources (CLEARWATER)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2018,

Our project consortium will design, build, install and operate an open ocean 4.5MW tidal energy farm in the Inner Sound in the Pentland Firth, off the Northern coast of Scotland. The project (“Clearwater”) will demonstrate the technical and economic feasibility of a multi-turbine tidal energy array, an essential step to catalyse development of commercial projects in the EU ocean energy industry. P ...
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 4

 TERMINÉ 

Benefit-sharing for an equitable transition to the green economy - the role of law (BENELEX)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2018,

Can benefit-sharing address the equity deficit within the green economy? This project aims to investigate benefit-sharing as an under-theorised and little-implemented regulatory approach to the equity concerns (disregard for the special circumstances of developing countries and of indigenous peoples and local communities) in transitioning to the green economy.Although benefit-sharing is increasing ...
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 3

 TERMINÉ 

Impacts and risks from higher-end scenarios: Strategies for innovative solutions (IMPRESSIONS)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2018,

IMPRESSIONS will provide empirically-grounded, transformative science that quantifies and explains the consequences of high-end climate scenarios for both decision-makers and society. IMPRESSIONS will develop and apply a novel participatory methodology that explicitly deals with uncertainties and strong non-linear changes focussing on high-end climate change, but also including intermediate warmin ...
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 25

 TERMINÉ 

Practical Organic Synthesis Inspired by Nature (POSIN)

Date du début: 1 oct. 2014, Date de fin: 30 sept. 2018,

"The aim of this research is to use nature as a source of inspiration and direction to improve and develop synthetic organicchemistry. Through targeted total syntheses I will investigate and learn about the highly sophisticated way nature utilizesdimerizations to rapidly generate molecular complexity. I will demonstrate the power of this biomimetic strategy bysynthesizing a wide variety of complex ...
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 1

 TERMINÉ 

Simplifying the non-planar sector of gauge theory (Nonplanar)

Date du début: 1 oct. 2014, Date de fin: 30 sept. 2018,

In recent years, there has been considerable progress on our understanding of scattering amplitudes in the planar limit of gauge theory. The non-planar parts of the theory have seen much less progress. However, some new ideas indicate that information from the planar sector is sufficient to determine properties of the full, non-planar theory when combined with a new class of Jacobi identities. As ...
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 1

 TERMINÉ 

"Health and the Understanding of Metabolism, Aging and Nutrition" (HUMAN)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2018,

"Recently intense research identified around 4,000 single nucleotide polymorphisms (SNPs) associated with human age related diseases such as metabolic disorders. Despite their highly significant association to pathology, the functional role of these genetic variants is, in most cases, yet to be elucidated. The evolutionary distance of most animal models from humans represents a major limitation fo ...
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 17

 TERMINÉ 

Sparse Representations and Compressed Sensing Training Network (SpaRTaN)

Date du début: 1 oct. 2014, Date de fin: 30 sept. 2018,

The aim of this Initial Training Network is to train a new generation of interdisciplinary researchers in sparse representations and compressed sensing, contributing to Europe’s leading role in scientific innovation. By bringing together leading academic and industry groups with expertise in sparse representations, compressed sensing, machine learning and optimization, and with an interest in appl ...
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 8

 TERMINÉ 

Atmospheric Carbon Capture (ACCA)

Date du début: 1 mai 2014, Date de fin: 30 avr. 2018,

"Carbon emissions from fossil fuel combustion and change in land use are forcing a rapid increase in atmospheric CO2 levels leading to climate change. The initial implementation of plans to reduce the levels of CO2 is based on a combination of increased use of renewable energy and the implementation of carbon capture and storage from industrial sources and power plants on a wide scale.Such actions ...
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 1

 TERMINÉ 

Tidal Demonstration for Energy Scheme (TIDES)

Date du début: 15 avr. 2013, Date de fin: 14 avr. 2018,

A full tidal array has not been installed anywhere, commercially to date. A number of the leading turbine manufacturers have part or full scale working prototypes which are under-going testing in various sites the majority of which are enclosed in semi-test environments. In order to move this nascent technology into the commercial arena and expedite market deployment, it is necessary to establish ...
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 7

 TERMINÉ 

Imaging Magnetism in Nanostructures using Electron Holography (IMAGINE)

Date du début: 1 avr. 2013, Date de fin: 31 mars 2018,

"Future developments in the control, functionalization and manipulation of magnetic nanoparticles and nanoscale magnetic devices require an understanding of collinear and non-collinear spin configurations and correlated changes of electronic structure on the sub-nanometer scale.In this project, an experimental methodology will be developed to allow magnetic spin structures in differently shaped na ...
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 3

 TERMINÉ 

The end-Cretaceous extinction and Paleogene recovery of mammals: evolution during a period of intense environmental change (BRUS)

Date du début: 1 mars 2014, Date de fin: 28 févr. 2018,

"How do organisms respond to environmental change? Answering this question is an essential challenge in contemporary scientific research, as it will help us understand—and better prepare for—the rapid pace of current climate change. A striking example of major environmental change in the geological record is the ~30 million years bracketing the Cretaceous-Paleogene boundary (66 million years ago), ...
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 1

 TERMINÉ 

Use of EGF-R antagonists for the treatment of chronic infections and tumor growth (EGF-R for immunity)

Date du début: 1 mars 2014, Date de fin: 28 févr. 2018,

FoxP3 expressing regulatory T-cells play an important role in the induction of peripheral tolerance and the prevention of auto-immune responses. How the functionality of regulatory T-cells is regulated at the site of inflammation remains poorly understood. We just recently discovered that the functionality of regulatory T-cells is regulated via the EGF-R that is expressed by activated regulatory T ...
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 1

 TERMINÉ 

Training in Multiscale Analysis of multi-Phase Particulate Processes (T-MAPPP) (T-MAPPP)

Date du début: 1 mars 2014, Date de fin: 28 févr. 2018,

"Dry, wet and multiphase particulate materials constitute over 75% of raw material feedstock to industry. Despite their significance, many industrial particulate processes display unpredictable behaviour due to both their multiscale nature and the coexistence of different phases: this leads to undesirable losses in resources, energy, money and time. Considerable progress can be achieved using mult ...
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 11

 TERMINÉ 

Learning and Testing Structured Probability Distributions (LTSPD)

Date du début: 1 mars 2014, Date de fin: 28 févr. 2018,

"The research topic of the current proposal lies within the area of Algorithms and Complexity.The goal of this proposal is to advance a research program of developingcomputationally efficient algorithms for learning and testinga wide range of natural and important classes of probability distributions.We live in an era of “big data,” where the amount of data that can be brought to bearon questions ...
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 1

 TERMINÉ 

Low-valent main-group systems for reversible small molecule activation (MainGroupAct)

Date du début: 1 mars 2014, Date de fin: 28 févr. 2018,

Catalysis is a pivotal technology in today’s society, enabling efficient access to complex molecular architectures. Metal-catalysed processes such as Pd-catalysed cross couplings or olefin metathesis are fundamental in synthetic and industrial chemistry. Many of these processes use scarce (and correspondingly expensive) metals. The scarcity of these metals - and the potential for geopolitical inst ...
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 1

 TERMINÉ 

Neuronal circuits and synaptic mechanisms of experience-dependent plasticity (In vivo Plasticity)

Date du début: 1 mars 2014, Date de fin: 28 févr. 2018,

The overall theme of this proposal is to understand how cortical circuits are modified by experience. I propose to determine the cellular and synaptic basis of long-term experience-dependent potentiation of visual responses in the adult primary visual cortex. My hypothesis is that changes in cortical inhibition from specific classes of interneurons underlie the potentiation of excitatory neuron re ...
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 1

 TERMINÉ 

European Facility for Airborne Research in Environmental and Geo-sciences (EUFAR2)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,

EUFAR aims at providing researchers with Open Access to the airborne facilities the most suited to their needs. EUFAR thus allocates Transnational Access to 21 installations, develops a culture of co-operation between scientists and operators, and organizes training courses to attract young scientists to airborne research. To improve the quality of the service, EUFAR supports the experts on airbor ...
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 24

 TERMINÉ 

Analysis of the interplay between genetic mutation and altered cellular metabolism in renal neoplasia (RENAL CANCER)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,

Defining and characterising the defective genes in hereditary cancer syndromes has advanced our understanding of cellular function and disease mechanisms. Interestingly, some of these genes have been directly implicated in metabolic dysregulation, thus providing a link between genetic mutation and altered metabolism in cancer. One such syndrome, hereditary leiomyomatosis and renal cell cancer (HLR ...
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 2

 TERMINÉ 

Studies on the role of Plk1 localization and activity in the regulation of microtubule dynamics during mitosis (MITDYN)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2017,

"Mitosis is a critical phase of the cell cycle where chromosome are equally partitioned to daughter cells using the structure and forces from the mitotic spindle apparatus to power this process. The spindle is made of hundreds of dynamic microtubule polymers. Within the spindle, subpopulations of microtubules are tightly controlled by microtubule associated proteins and signaling gradients to achi ...
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 1

 TERMINÉ 

Energy efficient MOF-based Mixed Matrix Membranes for CO2 Capture (M4CO2)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2017,

"The key objective of the M4CO2 project is to develop and prototype Mixed Matrix Membranes based on highly engineered Metal organic frameworks and polymers (M4) that outperform current technology for CO2 Capture (CO2) in pre- and post-combustion, meeting the energy and cost reduction targets of the European SET plan.By applying the innovative concept of M4 by a consortium of world key players, con ...
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 17

 TERMINÉ 

Upscaling human insulin-producing beta cell production by efficient differentiation and expansion of endoderm progenitors (HumEn)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2017,

Despite progress in producing beta cells from human pluripotent stem cells (hPSCs) in recent years, full differentiation cannot be obtained in vitro. The HumEn project hypothesises that a fundamental understanding of the coupling between endodermal progenitor expansion and differentiation is relevant for elucidating how to a) generate glucose-responsive beta cells from hPSCs in vitro, and b) gener ...
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 9

 TERMINÉ 

ADVanced communicAtions and iNformaTion processing in smArt Grid systEms (ADVANTAGE)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2017,

"Smart Grid systems represent a significant new technology to provide more energy efficient power delivery systems that reduce carbon emissions and can handle a mix of energy sources from small scale renewable energy to large power stations. The design and implementation of the smart grid will be very complex, involving a large number of systems, layers and relationships. In order to make the infr ...
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 8

 TERMINÉ 

Logistic Efficiencies And Naval architecture for Wind Installations with Novel Developments (LEANWIND)

Date du début: 1 déc. 2013, Date de fin: 30 nov. 2017,

A new EU 7th Framework Programme project, “LEANWIND” (Logistic Efficiencies And Naval architecture for Wind Installations with Novel Developments) seeks to apply lean principles to the offshore wind farm project lifecycle. The primary LEANWIND objective is to provide cost reductions across the offshore wind farm lifecycle and supply chain through the application of lean principles and the developm ...
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 32

 TERMINÉ 

Operational Potential of Ecosystem Research Applications (OPERAs)

Date du début: 1 déc. 2012, Date de fin: 30 nov. 2017,

Human use and exploitation of the biosphere is increasing at such a pace and scale that the sustainability of major ecosystems is threatened, and may not be able to continue to function in ways that are vital to the existence of humanity. Re-framing environmental resource use has led to the emergence of the concepts of ecosystem services (ES) and natural capital (NC). This discourse indicates not ...
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 27

 TERMINÉ 

CACHE: CAlcium in a CHanging Environment (CACHE)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2017,

"Anthropogenic driven climate change is a global problem that will increasingly affect our world and It is essential that we train our future scientists in multidisciplinary approaches to enable them to tackle such complex problems. This ITN examines environmental calcium mobilisation and deposition in marine molluscs, species that have been highlighted as being particularly at risk under future c ...
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 10

 TERMINÉ 

"Land use change: assessing the net climate forcing, and options for climate change mitigation and adaptation" (LUC4C)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2017,

"LUC4C will advance our fundamental knowledge of the climate change - land use change interactions, and develop a framework for the synthesis of complex earth system science into guidelines that are of practical use for policy and societal stakeholders.Policies in support of climate change mitigation through land management, and the societal demand for other services from terrestrial ecosystems ar ...
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 15

 TERMINÉ 

Evolution of Shared Semantics in Computational Environments (ESSENCE)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2017,

"In everyday life, humans exhibit strong skills in resolving communication problems by re-negotiating what theymean. Modern-day computational systems, however, are lacking in resilience and robustness in this respect. Whenever different components with different vocabularies and models of meaning interact within distributed, open enviroments, they have to rely on their human designers’ abilities t ...
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 7

 TERMINÉ 

The impact of chromosomal instability on health: Molecular causes and consequences of aneuploidy (PLOIDYNET)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

Aneuploidy, an abnormal number of chromosomes, is a hallmark of cancer cells, affecting the majority of all human tumours. Aneuploidy arises when errors occur during mitosis, as the duplicated chromosomes are distributed between the two new daughter cells. Paradoxically, aneuploidy appears to have detrimental consequences for the physiology of untransformed cells in vitro, inhibiting rather than s ...
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 14

 TERMINÉ 

European stem cell consortium for neural cell replacement, reprogramming and functional brain repair (Neurostemcellrepair)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

Neurostemcellrepair aims at taking human stem cells through the final steps toward clinical application in cell replacement therapy for neurological disorders. PD will be taken as the prototypical disease because stem cell therapy is now close to clinical translation. Moreover, we will tackle next generation issues pertaining to stem cells at a basic level and develop new approaches and novel cell ...
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 13

 TERMINÉ 

IMAging GEnetics for MENtal Disorders (IMAGEMEND)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

"Mental disorders are leading causes of disability, absence from work and premature retirement in Europe. While magnetic resonance imaging (MRI) facilities are broadly available and a vast research literature exists, few neuroimaging applications have reached clinical practice in psychiatry. A major problem is that mental illnesses are currently diagnosed as discrete entities defined clinically. I ...
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 15

 TERMINÉ 

"Judging Political Violence: Histories, Norms and Contestations" (JUDGEPOL)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

"This research project aims to advance Political Theory’s contribution to the interdisciplinary study of political violence. The 21st century presents us with new forms of political violence that challenge our moral and cognitive capacities. Faced with controversies over genocide, terrorism, and torture, scholars must both reflect on what is actually happening and offer guidelines about how to all ...
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 1