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Translational study on the antigen presenting properties of human vs mouse B cell subpopulations (BcellsMiceToMen)
Date du début: 15 avr. 2010, Date de fin: 14 avr. 2013,
Our recent results on antitumor effects of carbohydrate mimotope peptides (CMP) suggest a possible role of carbohydrate reactive B cell subpopulations as cellular adjuvants. As an abundant alternative of dendritic cells, CD40-activated B cells can efficiently present specific antigens being expandable for several weeks. Some B cells can be sufficiently detrimental to warrant anti-B cell therapy in ...
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