4 projets européens trouvés
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TERMINÉ
EURO EWING Consortium – International Clinical Trials to Improve Survival from Ewing Sarcoma (EEC)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2018,
Ewing Sarcomas (ES) are fatal, rare bone cancers particularly affecting young people. About 60% of patients achieve long term survival with current treatment but there has been no improvement in this proportion for 25 years. Treatment is unsuccessful because chemotherapy fails to prevent the development of, or to effectively treat established, metastases. In addition, of the 600 new cases of ES o ...
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21
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TERMINÉ
Optimized Diagnostics for Improved Treatment Stratification in Invasive Fungal Diseases (FUNGITECT)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,
"Invasive fungal disease (IFD) is a leading cause of morbidity and mortality in the growing number of immunocompromised individuals, including particularly cancer patients, and bone-marrow or organ transplant recipients. The majority of IFD events are still caused by Candida and Aspergillus species, but there is an increasing incidence of resistant or previously uncommon moulds, yeasts and Zygomyc ...
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6
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TERMINÉ
Molecular Mechanisms of Fungal Pathogen Host Interactions (ImResFun)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,
ImResFun shall provide state-of-the-art training in infectious disease research and medical immunology targeting the most common human fungal pathogens, the opportunistic Candida species. The key objectives of ImResFun are: (i) to understand how immune cells and infected organs respond to invasion by Candida spp, (ii) to decipher host-defense mechanisms mediating pathogen elimination, and (iii) to ...
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12
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TERMINÉ
Targeted Modulation of Immune-System Responses in Cell Therapies (MODICELL)
Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,
Cell-based immunotherapies are a modern treatment approach holding promise to utilize nature’s own power to treat diseases that develop on the ground of immune system aberrations. Such diseases include cancer that develops and progresses via immune escape and on the other hand rejection of transplanted organs that need to be accepted by the immune system. Because the functions of distinct immune c ...
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