10 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Yeast Cell Factories: Training Researchers to Apply Modern Post-Genomic Methods In Yeast Biotechnology (YEASTCELL)
Date du début: 1 sept. 2013, Date de fin: 31 août 2017,
"The YEASTCELL ITN will train 11 Early Stage Researchers for productive careers as research scientists and leaders in the public or private yeast biotechnology sectors. Yeast biotechnology spans fundamental and applied research and is an area with an immediate need for highly trained researchers to advance knowledge and to develop new applications. The training consortium comprises 9 Public Sector ...
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13
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TERMINÉ
Scaffold Based Supramolecular Architectures as Protein Epitope Mimetics for Biomedical Applications (3D BIOMIMETICS)
Date du début: 1 mars 2014, Date de fin: 31 août 2016,
Synthetic molecules that mimic the structure of the part of a folded protein involved in recognition events (protein epitope mimetics, PEMs) can access biological targets previously deemed as “undruggable” and are considered as a potential source of future therapeutics. So far, PEMs could effectively mimic only individual secondary structure elements of peptides and proteins. The major goal of thi ...
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1
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TERMINÉ
HEMatopoietic cell IDentity : genetic and epigenetic regulation in normal and malignant hematopoiesis (HEM_ID)
Date du début: 1 nov. 2011, Date de fin: 31 oct. 2015,
In hematopoiesis, failure to maintain homeostasis and regenerative functions result in a multitude of hematological malignancies, including myelodysplastic syndromes, lymphomas and leukemias, that represent a medical challenge and a large socioeconomic burden because of the large number of affected patients of all age groups. Although hierarchical organization of the hematopoietic system has been ...
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12
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TERMINÉ
Novel high-performance enzymes and micro-organisms for conversion of lignocellulosic biomass to bioethanol (NEMO)
Date du début: 1 mai 2009, Date de fin: 30 avr. 2013,
The NEMO project provides novel efficient enzymes and microbes for 2nd generation bioethanol production. It generates through metabolic engineering and mutagenesis & screening approaches robust yeast strains that have a broad substrate range and can (co-)ferment C6 and C5 sugars to ethanol with high productivity (rate and yield), and that are significantly more stress tolerant, i.e. inhibitor, eth ...
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21
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TERMINÉ
Eukaryotic unicellular organism biology – systems biology of the control of cell growth and proliferation (UNICELLSYS)
Date du début: 1 avr. 2008, Date de fin: 31 mars 2013,
The overall objective of UNICELLSYS is a quantitative understanding of fundamental characteristics of eukaryotic unicellular organism biology: how cell growth and proliferation are controlled and coordinated by extracellular and intrinsic stimuli. Achieving an understanding of the principles with which bio-molecular systems function requires integrating quantitative experimentation with simulation ...
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20
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TERMINÉ
European Network for Cell Imaging and Tracking Expertise (ENCITE)
Date du début: 1 juin 2008, Date de fin: 30 nov. 2012,
"Cell therapy can be defined as the transplantation of living cells for the treatment of medical disorders. Three different principles underlie the increasing interest in cell therapy. 1. Transplanted cells used as an “active drug” 2. Transplanted cells used to replace damaged and degenerated tissue. 3. Cells used as a drug delivery vehicle. Promising results have been obtained in pre-clinical and ...
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30
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TERMINÉ
High Resolution Microscopy in the DNA Damage Response (Image DDR)
Date du début: 1 nov. 2008, Date de fin: 31 oct. 2012,
Background: The DNA damage response (DDR) is a specialised stress response fundamental to maintaining genome integrity and suppressing tumour formation. Traditional molecular and cellular biology, combined with genetics and biochemistry, have led to an understanding of the architecture of the DDR in a variety of model organisms and in human cells. These studies have employed populations of cells/ ...
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6
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TERMINÉ
Normalisation of immune reactivity in old age – from basic mechanisms to clinical application (TOLERAGE)
Date du début: 1 avr. 2008, Date de fin: 30 sept. 2012,
"When restoration of the immune response in older age is the target of basic and clinical research, boosting innate and adaptive immunity, e.g. by more efficient vaccination strategies, is the general approach. However, TOLERAGE has a fundamentally different focus, i.e. restoring the age-dependent decline of auto-tolerance that underlies the development of the paradigmatic age-associated diseases ...
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10
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TERMINÉ
Cis-regulatory logic of the transcriptional control in neural stem cells (CISSTEM)
Date du début: 1 oct. 2008, Date de fin: 31 mars 2012,
"Neural stem cells (NSCs) have emerged as a major topic in neurobiology. The persistence of multipotent cells in the adult mammalian brain offers a realistic chance for the treatment of neurodegenerative diseases. It is thus crucial to understand NSCs from as many as possible angles (e. g. cellular and molecular biology), in order to better isolate and successfully manipulate them. CISSTEM present ...
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9
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TERMINÉ
Systems Biology as a Driver for Industrial Biotechnology (SYSINBIO)
Date du début: 1 déc. 2008, Date de fin: 30 nov. 2011,
"Metabolic engineering is an applied science focusing on developing new cell factories or improving existing ones. Metabolic engineering is an enabling science, and distinguishes itself from applied genetic engineering by the use of advanced analytical tools for identification of appropriate targets for genetic modifications and the use of mathematical models to perform in silico design of optimiz ...
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