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15 projets européens trouvés

Recherche sur 125080 projets européens

 TERMINÉ 

Standardization and Development of Assays for Assessment of Influenza Vaccines Correlates of Protection (FLUCOP)

Date du début: 1 mars 2015, Date de fin: 29 févr. 2020,

Background: Influenza viruses cause annual epidemic and occasional pandemics, both of which induce significant morbidity and mortality. Influenza infections affect all age groups but children and adults over the age of 65 are at most risk of developing severe disease.Vaccination is the most effective approach to reduce the impact of annual influenza outbreaks and potential pandemics, however, the ...
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 26

 TERMINÉ 

Nanotherapeutics for antibiotic resistant emerging bacterial pathogens (NAREB)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,

Increase in antibiotic resistance is a global concern worldwide. The project NAREB's main objective is the optimization of several nanoformulations of antibacterial therapeutics in order to improve the therapy of multi-drug resistant (MDR) tuberculosis (TB) and MRSA infections in European MDR patients.NAREB will address the problem of drug bioavailability inside the infected macrophages, transport ...
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 16

 TERMINÉ 

European Research Infrastructures for Poverty Related Diseases (EURIPRED)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2017,

HIV/AIDS, Tuberculosis (TB) and Malaria alone account for more than six million deaths worldwide every year. Despite substantial efforts made in recent years, Poverty Related Diseases are still spreading. New therapeutic interventions are therefore urgently required to combat Poverty Related Diseases. The existence of a well-developed HIV/TB/Malaria infrastructure presents a prime opportunity to a ...
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 18

 TERMINÉ 

Combinatorial immunization strategy to educate the immune system towards cross recognition and coverage against antigenic drift in seasonal influenza virus exposure (EDUFLUVAC)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2017,

"As current influenza vaccines only afford limited protection against seasonal as well as pandemic influenza, and require regular updating, the development of a “universal” influenza vaccine that can provide broad coverage against different strains within a subtype or even across subtypes has become a key health care priority in both industrialized and low and middle income countries. EDUFLUVAC ai ...
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 9

 TERMINÉ 

Advanced Immunization Technologies (ADITEC)

Date du début: 1 oct. 2011, Date de fin: 30 sept. 2017,

Vaccines so far have been developed mostly by following an empiric approach. To prevent and possibly cure unresolved and emerging infectious diseases we need to fully exploit the potential of the human immune system. Progress in science and technology makes it possible to achieve what was previously deemed impossible. The scope of this project is to produce knowledge necessary to develop novel and ...
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 53

 TERMINÉ 

Universal Influenza Vaccines Secured (UNISEC)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

UNISEC brings together a European consortium of 3 University partners, 5 National Health Institutes and 3 SMEs, all with leading expertise in influenza vaccine research and development, to work on promising recently developed concepts for a universal influenza vaccine. The consortium is exceptionally strong, interdisciplinary and intersectional in nature, and encompasses a unique combination of sc ...
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 15

 TERMINÉ 

Biomarkers For Enhanced Vaccine Safety (BIOVACSAFE)

Date du début: 1 mars 2012, Date de fin: 31 déc. 2016,

BioVacSafe is a concise consortium of selected academic, public, and SME participants used to co-working in industry-led projects, organised into focused Activity Cores to generate knowledge and tools to benchmark licensed vaccine reactogenicity, and create practical and generalizable guidelines and techniques to enhance immunosafety of novel vaccines from pre-development to post-marketing surveil ...
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 24

 TERMINÉ 

Addictions and Lifestyles In Contemporary Europe – Reframing Addictions Project (ALICE RAP)

Date du début: 1 avr. 2011, Date de fin: 31 mars 2016,

ALICE RAP is a Europe wide project of 43 partner research institutions involving 107 researchers from 25 European countries providing 1000 months of a plurality of scientific endeavour to analyse the place and challenges of addictions and lifestyles to the cohesion, organization and functioning of contemporary European society. Through integrated multidisciplinary research, a wide range of factors ...
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 46

 TERMINÉ 

ToxBank – Supporting Integrated Data Analysis and Servicing of Alternative Testing Methods in Toxicology (TOXBANK)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2015,

ToxBank establishes a dedicated web-based warehouse for toxicity data management and modelling, a ‘gold standards’ compound database and repository of selected test compounds, and a reference resource for cells, cell lines and tissues of relevance for in vitro systemic toxicity research carried out across the FP7 HEALTH.2010.4.2.9 Alternative Testing Strategies SEURAT program. The project develops ...
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 10

 TERMINÉ 

Stem Cells for Relevant Efficient Extended and Normalized Toxicology (SCR&TOX)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2015,

In the development of products for use by humans it is vital to identify compounds with toxic properties at an early stage of their development, to avoid spending time and resource on unsuitable and potentially unsafe candidate products. Human pluripotent stem cell lines offer a unique opportunity to develop a wide variety of human cell-based test systems because they may be expanded indefinitely ...
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 16

 TERMINÉ 

European Primate Network: Advancing 3Rs and International Standards in Biological and Biomedical Research (EUPRIM-NET II)

Date du début: 1 janv. 2011, Date de fin: 30 juin 2015,

Biomedical research depends on the availability of living non-human primates and biological material with primate origin. The need for animal research using non-human primates is therefore recognised by all governments that support internationally competitive biomedical research aimed at addressing the world’s most pressing medical challenges. While essential for biomedical research owing to their ...
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 13

 TERMINÉ 

"Neutralizing antibodies against botulinum toxins A,B,E" (ANTIBOTABE)

Date du début: 1 sept. 2010, Date de fin: 28 févr. 2015,

"Botulinum neurotoxins (BoNTs), the most toxic substances known, are susceptible for use as bioweapons (listed as class A agents by CDC). Currently licensed animal derived antibodies or F(ab’)2 preparations, are at a high risk of inducing adverse effects and their privately-owned stockpiles are limited. In this project, we will target the most lethal types of BoNTs: A (subtypes A1 and A2), B (B1 a ...
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 11

 TERMINÉ 

Embryonic Stem cell-based Novel Alternative Testing Strategies (ESNATS)

Date du début: 1 avr. 2008, Date de fin: 30 sept. 2013,

"ESNATS aims at developing a novel toxicity test platform based on embryonic stem cells (ESC), especially human ESC (hESC), to accelerate drug development, reduce R&D costs and propose a powerful alternative to animal tests (3 Rs). ESNATS will address current drug-testing shortcomings: - testing takes place late in the development cycle - animal test systems bear the risk of non-prediction due to ...
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 34

 TERMINÉ 

Social Capacity Building for Natural Hazards: Toward More Resilient Societies (CapHaz-Net)

Date du début: 1 juin 2009, Date de fin: 31 mai 2012,

The main objectives of CapHaz-Net are to identify and assess existing practices and policies for social capacity building in the field of natural hazards and to elaborate strategies and recommendations for activities to enhance the resilience of European societies to the impacts of natural hazards. This will be achieved by bringing together different scientific disciplines and by enhancing and fos ...
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 8

 TERMINÉ 

Nasal Pandemic Influenza Vaccine (NASPANVAC)

Date du début: 1 mai 2008, Date de fin: 30 avr. 2012,

"The project is being undertaken in response to the need to develop an effective, user friendly, heat stable vaccine to control the highly pathogenic form of avian influenza virus (H5 and H7 subtypes) which has the potential to cause another global influenza pandemic. The overall objective of this programme is to develop a nasal avian influenza vaccine using ChiSys® (chitosan), which is a chitosan ...
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 8