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The interaction of Lassa virus with its cellular receptor alpha-dystroglycan (Lassa virus receptor)
Date du début: 1 mars 2008, Date de fin: 29 févr. 2012,
The arenavirus Lassa fever virus (LFV) causes a severe viral hemorrhagic fever in humans with over 300, 000 infections and thousands of deaths annually. Fatal LFV infection is characterized by marked immunosuppression of the patient, resulting in uncontrolled viral infection with progressive hemorrhagic disease and shock. Since death occurs in absence of a significant anti-viral immune response, t ...
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