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Management of Resistance to Tyrosine Kinase Inhibitors with Advanced Nanosystems (NANORESISTANCE)
Date du début: 1 nov. 2011, Date de fin: 31 oct. 2015,
NANORESISTANCE introduces for the first time (i) receptor -independent targeting of Epidermal Growth Factor Receptor-kinase activity, (ii) nuclear delivery of anti-Epidermal Growth Factor Receptor therapy with novel grafting techniques and (iii) the deciphering of resistance and lack of responsiveness to anti-EGFR therapies in the preclinical setting with mathematical models of interstitial biodi ...
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