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Characterization of the role of histone H1 and its post-translational modifications in the functional regulation of chromatin (HISTONE H1 FUNCTION)
Date du début: 1 oct. 2007, Date de fin: 30 sept. 2009,
Histone H1 participates in both the establishment and stabilization of high-order of chromatin organization through its binding to the internucleosomal DNA. H1 seems to play an important role in regulation of chromatin functions, and particularly in the regulation of gene expression and chromosome condensation.However, our understanding of H1 function is based mainly on in vitro studies and we do ...
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