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Metformin for treatment of polycystic ovary syndrome in children (METFIZZ)

Date du début: 1 oct. 2013, Date de fin: 31 mars 2017,

PCOS, a common disorder affecting 5-10% of women of reproductive age is characterized by cystic ovarian morphology, androgen excess, and/or irregular periods and emerges during or shortly after puberty. The common off-label use of metformin for treating PCOS in children appears to have no greater risk than that in adults; drug tolerance is good with limited adverse effects. However, clinical trial ...
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