4 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Clinical study in Parkinson's disease with two unique goals: 1) Proof-of-concept of CDNF protein for disease modification; 2) Validation of clinically tested device for intracerebral drug delivery (TreatER)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2019,
The main focus of TreatER is conducting a randomized, placebo-controlled, first-in-human, proof-of-concept, safety and efficacy study of intracerebrally administered CDNF protein therapy in patients with Parkinson’s disease (PD), using a neurosurgically implanted Drug Delivery System (DDS), which will also be clinically validated in the study. Thus the TreatER project has two independent goals, ei ...
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12
Participants partenaires
TERMINÉ
Phase II clinical trial of PDGF-BB for the neurological regeneration and recovery in Parkinson´s disease (NRT)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,
...nsure proper governance of the clinical study, compliant with fundamental ethical principles of European regulations concerning studies on “advanced therapies medicinal products”. PD patient associations and experts in ethics will assist the project with patient information and recruitment strategies. Internal training sessions, external meetings and dissemination of results will be coordinated b ...
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10
Participants partenaires
TERMINÉ
Personal Health Device for the Remote and Autonomous Management of Parkinson's Disease (REMPARK)
Date du début: 1 nov. 2011, Date de fin: 30 avr. 2015,
...s from four medical centres. The consortium is formed by medical and technical renowned specialists, and PD patients are represented through the participation of the European Parkinson's Disease Association.
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11
Participants partenaires
TERMINÉ
Restorative Plasticity At Corticostriatal Excitatory Synapses (REPLACES)
Date du début: 1 nov. 2008, Date de fin: 30 avr. 2013,
"Long-lasting, activity-dependent synaptic changes are thought to underlie the ability of the brain to translate experiences into memories and seem to represent the cellular model underlying learning and memory processes. Alteration of brain plasticity may lead to the motor and cognitive disturbances observed in neurodegenerative diseases. Therapeutic approaches targeting synaptic plasticity could ...
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