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The development of a novel therapeutic vaccine for the selective treatment of the autoimmune disorder, Graves’ disease (DAVIAD)
Date du début: 1 déc. 2013, Date de fin: 30 nov. 2017,
...ive response to self antigens. This proposal focuses on the development of an antigen specific vaccine therapy to reinstate immune tolerance to Graves’ disease. The selected peptides behave as apitopes (antigen processing independent epitopes) and bind to MHC class II molecules in the correct confirmation to induce tolerance. In the first instance DAVIAD will further characterise antigen specific ...
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