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...erpenoid found in Withania somnifera plants. The aim of DrugTissueCult is to generate plant tissue culture lines that produce very high amounts of Thapsigargin or Withaferin A. The industrial partner Alkion Biopharma has a patented technology that will be used to create a large collection of plant tissue cultures, which will be selected for significant production of Thapsigargin and Withaferin A. ...

Mankind is continually screening low-molecular-weight compounds from a plethora of synthetic and natural sources in the search for molecules with novel or superior pharmaceutical, agrochemical or other biological activities. In this regard, plants are a potentially rich source of bioactive molecules. Because of their extreme diversity and complex chemistry, however, plant metabolism is still under ...