2 projets européens trouvés
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TERMINÉ
Multimodal Imaging of rare Synucleinopathies (MultISyn)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2018,
Despite remarkable progress in the understanding of the molecular pathogenesis of neurodegenerative diseases (NDD), no causative or disease-modifying treatment is currently available. Aggregation of misfolded proteins are thought to play a crucial role in the pathogenesis, but attempts to exploit this knowledge for novel treatments have not been successful. Also, pathogenetically relevant biomarke ...
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Participants partenaires
TERMINÉ
Reach α-synuclein-dependent neurodegeneration: clinical development of therapeutic AFFITOPE vaccines for Parkinson’s disease and multisystem atrophy (SYMPATH)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,
The goal of SYMPATH is to advance clinical development of therapeutic vaccines targeting α-synuclein (aSyn)-driven neurodegenerative diseases (ND). It addresses Parkinson’s disease (PD) and multiple system atrophy (MSA), two synucleopathies, for which no causal therapy exists. Ultimately, both lead to patient disability and death, which along with patient number (PD) and age of onset (MSA, PD) def ...
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