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 TERMINÉ 
Over 130,000 children born in Europe every year will have a congenital anomaly (CA; birth defect). These CAs, which are often rare diseases, are a major cause of infant mortality, childhood morbidity and long-term disability. EUROCAT is an established European network of population-based registries for the epidemiologic surveillance of CAs. EUROlinkCAT will use the EUROCAT infrastructure to suppor...
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 25

 TERMINÉ 
This proposal will develop new transparent p-type semiconductors that will make dye-sensitized solar cells (DSC) a vastly more efficient and a realistic prospect for carbon-free energy generation worldwide. Two key challenges will be addressed: (1) a means of converting NIR radiation to increase the amount of sunlight utilised from 35% to over 70%; (2) a means of storing the energy. Almost all the...
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 2

 TERMINÉ 
ImpleMentAll will develop, apply, and evaluate tailored implementation strategies in the context of on-going eHealth implementation initiatives in the EU and beyond. Common mental health disorders account for an alarming proportion of the global burden of disease. Being regarded as an evidence-based psychotherapeutic eHealth intervention, Internet-based Cognitive Behavioural Therapy (iCBT), has th...
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 19

 TERMINÉ 

PRevention Of Malnutrition In Senior Subjects in the EU (PROMISS)

Date du début: 1 avr. 2016, Date de fin: 31 mars 2021,

PROMISS (PRevention Of Malnutrition In Senior Subjects in the EU) is a multi-country project aiming to turn the challenge of tackling malnutrition in community-dwelling older persons into an opportunity for healthy ageing for the future. The PROMISS consortium contains worldwide expertise in epidemiology, clinical trials, geriatrics, nutrition, physical activity, microbiomics, as well as in behavi...
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 24

 TERMINÉ 
The PATHSENSE (Pathogen Sensing) ETN will bring together an interdisciplinary team of world-leading researchers from Europe to tackle a highly ambitious scientific project, focusing on the molecular mechanisms of sensory perception in bacterial pathogens. PATHSENSE will establish an innovative doctoral training programme that will deliver 13 PhD graduates and high-impact scientific outputs. The re...
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 14

 TERMINÉ 
Strength2Food is a 5-year, €6.9 million project to improve the effectiveness of EU food quality schemes (FQS), public sector food procurement (PSFP) and to stimulate Short Food Supply Chains (SFSC) through research, innovation and demonstration activities. Our 30-partner consortium representing 11 EU and 4 non-EU countries combines leading academic, communication, SME and stakeholder organisations...
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 31

 TERMINÉ 

Soil Care for profitable and sustainable crop production in Europe (SOILCARE)

Date du début: 1 mars 2016, Date de fin: 28 févr. 2021,

European crop production is to remain competitive while reducing environmental impacts, requiring development and uptake of effective soil improvingcropping systems. The overall aim of SOILCARE is to identify and evaluate promising soil-improving cropping systems and agronomictechniques increasing profitability and sustainability across scales in Europe. A trans-disciplinary approach will be used ...
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 29

 TERMINÉ 

Innovative Nanowire DEvicE Design (INDEED)

Date du début: 1 févr. 2017, Date de fin: 31 janv. 2021,

Nanowires (NWs) exhibit unique properties that make them potential building blocks for a variety of next generation NanoElectronics devices. Recent advances have shown that NWs with predefined properties can be grown, offering a new paradigm enabling functional device prototypes including: biosensors, solar cells, transistors, quantum light sources and lasers. The critical mass of scientific knowl...
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 12

 TERMINÉ 
inteGRIDy aims to integrate cutting-edge technologies, solutions and mechanisms in a scalable Cross-Functional Platform connecting energy networks with diverse stakeholders, facilitating optimal and dynamic operation of the Distribution Grid (DG), fostering the stability and coordination of distributed energy resources and enabling collaborative storage schemes within an increasing share of renewa...
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 31

 TERMINÉ 
The management of febrile patients is one of the most common and important problems facing healthcare providers. Distinction between bacterial infections and trivial viral infection on clinical grounds is unreliable, and as a result innumerable patients worldwide undergo hospitalization, invasive investigation and are treated with antibiotics for presumed bacterial infection when, in fact, they ar...
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 19

 TERMINÉ 
Train2Target is a multidisciplinary European Training Network built to address the challenge of the discovery of alternative antimicrobials. Innovative strategies to deliver a next generation of drugs are urgently needed. The alarming threats and spread of multi-drug resistant bacteria is currently leaving clinicians with very limited options to combat infections especially those from Gram-negativ...
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 11

 TERMINÉ 

Translational Research Network in Prostate Cancer (TransPot)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

The Translational Research Network for Prostate Cancer (TransPot) program adopts an innovative, multidisciplinary approach, providing highly sought-after, effective solutions for incurable prostate cancer (PC).The TransPot scientific objective is to obtain an unmatched depth of molecular, mechanistic and informatics systems-level disease understanding in order to improve the prognosis and treatmen...
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 11

 TERMINÉ 

Children’s Liver Tumour European Research Network (ChiLTERN)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

Liver cancer in the paediatric population is rare with an incidence approximately 1-1.5 per million population. The commonest tumour seen in the childhood population is hepatoblastoma (HB), usually seen in young children and infants. Much rarer (about 10% of paediatric liver cancers) is hepatocellular carcinoma (HCC), usually seen in the teenage population and sometimes associated with underlying ...
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 21

 TERMINÉ 
The Directive 2009/128/EC sets rules in EU for the sustainable use of pesticides to reduce the risks and impacts of pesticide use on people's health and the environment. Among the listed actions there is the promotion of low pesticide-input management including non-chemical methods. In parallel several chemical active ingredients have been banned because of toxicity concerns. The result is that gr...
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 11

 TERMINÉ 
The problem: finding the right patient for the right treatmentDespite a large and growing disease burden in osteoarthritis (OA), many pharmaceutical companies have de-emphasized or even abandoned OA drug development due to perceived hurdles. Crucial in this is the lack of appropriate outcome measures that can robustly identify patient benefit from a specific therapy. The lack of specific and sensi...
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 25

 TERMINÉ 
In order to achieve a more complete understanding of neocortical brain functions in health and disease, we need to delineate the computations of specific cell populations and how they dynamically exert their impact on connected target neurons. Here, I propose to investigate the functions of neurons in layer-6 of primary visual cortex (V1) and their influence on connected neurons, i) in the lateral...
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 1

 TERMINÉ 

Resituating the local in cohesion and territorial development (RELOCAL)

Date du début: 1 oct. 2016, Date de fin: 30 sept. 2020,

There is an increasing need for developing European Union Cohesion Policy in terms of greater sensitivity towards territorial specificities, more supportive of community-based development and the facilitation of greater civic participation. This also relates to the concern over decreasing identification with the European project among the population. Place-based development, endogenous regional de...
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 13

 TERMINÉ 
The “NDTonAIR” consortium involves Universities, Research Organisations and major European companies working on new Non-Destructive Testing (NDT) and Structural Health Monitoring (SHM) techniques for aerospace, of which both are key technologies. The goal is to train a new generation of scientists and engineers with a wide background of theoretical and experimental skills, capable of developing th...
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 11

 TERMINÉ 

Regulation of mitochondrial expression (REMIX)

Date du début: 1 oct. 2016, Date de fin: 30 sept. 2020,

Mitochondria are essential organelles found in every eukaryotic cell, required to convert food into usable energy. The mitochondrial oxidative phosphorylation (OXPHOS) system, which produces the majority of cellular energy in the form of ATP, is controlled by two distinct genomes: the nuclear and the mitochondrial genome (mtDNA). Mutations in mitochondrial genes encoded by either genome could caus...
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 9

 TERMINÉ 

The effects of early-life adversity on cognition: A comparative approach. (COMSTAR)

Date du début: 1 oct. 2015, Date de fin: 30 sept. 2020,

This research programme will investigate how adversity experienced early in life affects cognition in adulthood in two different long-lived species, humans and European starlings. Previous research has suggested that there might be cross-species similarities in the way early-life adversity shapes cognition, but the extent of commonalities has not been systematically investigated. I will focus on t...
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 1

 TERMINÉ 

L-form bacteria, biotechnology and disease (ELFBAD)

Date du début: 1 oct. 2015, Date de fin: 30 sept. 2020,

Despite the clear importance and multiple functions of the bacterial cell wall, many bacteria appear to be able to switch into a cell wall deficient or “L-form” state. L-forms are very heterogeneous in size and shape and generally require osmotic stabilisers, such as 0.5 M sucrose, for viability.However, by lacking the requirement for a cell wall, L-forms are completely resistant to common cell wa...
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 1

 TERMINÉ 

CLean INland SHipping (LIFE CLINSH)

Date du début: 1 sept. 2016, Date de fin: 31 août 2020,

Background Inland Waterway Transport (IWT) causes considerable emissions of the air pollutants NOx and PM10. Many European regions are struggling to tackle air quality problems, though the often expensive measures implemented to meet air quality limit values are mainly directed at industry and road transport. However, it is increasingly recognised that in...
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 17

 TERMINÉ 
HarmonicSS vision is to create an International Network and Alliance of partners and cohorts, entrusted with the mission of addressing the unmet needs in primary Sjogren Syndrome; working together to create and maintain a platform with open standards and tools, designed to enable secure storage, governance, analytics, access control and controlled sharing of information at multiple levels along wi...
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 39

 TERMINÉ 
In the real world, collision happens at every second - often results in serious accidents and fatalities. For example, there are more than 3560 people died from vehicle collision per day worldwide. On the other sector, autonomous unmanned aerial vehicles (UAVs) have demonstrated great potential in serving human society such as delivering goods to households and precision farming, but are restricte...
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 3

 TERMINÉ 
Parkinson’s disease (PD) is a major, chronic, non-communicable disease and the 2nd most frequent neurodegenerative disorder worldwide. Excess iron is primarily detected in the substantia nigra pars compacta, where dopaminergic neurons are exposed to high levels of oxidative stress produced by mitochondrial disorders and dopamine metabolism. Our previous preclinical, translational and pilot clinica...
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 17

 TERMINÉ 

Evidence-based ICT tools for weight loss maintenance (NoHoW)

Date du début: 1 mars 2015, Date de fin: 29 févr. 2020,

Most adults who try to lose weight fail to maintain it. Obesity is a key economic and healthcare challenge for Europe. Effective interventions and commercial programmes for weight loss are widely available, but most people re-gain their lost weight. Currently few comprehensive solutions exist to help Europeans manage weight loss maintenance (WLM).Current research suggests the most promising eviden...
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 16

 TERMINÉ 
Feed-a-Gene aims to better adapt different components of monogastric livestock production systems (i.e., pigs, poultry and rabbits) to improve the overall efficiency and to reduce the environmental impact. This involves the development of new and alternative feed resources and feed technologies, the identification and selection of robust animals that are better adapted to fluctuating conditions, a...
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 23

 TERMINÉ 
Background The presence of the invasive alien grey squirrel (Sciurus carolinensis) in the UK is detrimental to several native species and the overall health and resilience of affected woodland ecosystems. The native Eurasian red squirrel (Sciurus vulgaris) is particularly threatened by grey squirrels, but to date there has been no clear pan to stem its po...
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 7

 TERMINÉ 
VISION-DMD aims to advance clinical development of the orphan drug VBP15 as a new therapy to revolutionise care for all patients with Duchenne muscular dystrophy (DMD) by 2020, in line with IRDiRC goals. DMD is an incurable, rare muscle wasting disease; boys progressively weaken, lose ambulation and death occurs by early adulthood. Corticosteroids (CS) are widely recognised to increase muscle stre...
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 8

 TERMINÉ 
RUBICON will establish a global network for staff exchange of scientists and for research training focussed on connective tissue disorders. It will bring together leading scientific groups from 5 European and 5 non-European countries who will study the molecular and biomechanical factors involved in the pathophysiology of connective tissues, including tendons, cartilage and bone. The ambitious obj...
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 5

 TERMINÉ 

Collaborative cApacity Programme on Its Training-educAtion and Liaison (CAPITAL)

Date du début: 1 oct. 2016, Date de fin: 30 sept. 2019,

The aim of the project is to build a collaborative capacity community and deployment programme to support public and private stakeholders in the implementation of ITS (C-ITS) with training and educational resources which enable knowledge transfer about the benefits and deployment of ITS. The project will assist public and private stakeholders in developing their knowledge, skills, and abilities to...
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 11

 TERMINÉ 
The Transportation sector employs over 10 million persons in the EU today. At the same time, Transport is a social sector that is rapidly developing, changing and being influenced to the maximum extent by the development of automation, electrification and greening of transport, among others, thus facing problems in staffing its several domains with appropriate and qualified personnel. This fact, m...
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 21

 TERMINÉ 
ROLINCAP will search, identify and test novel phase-change solvents, including aqueous and non-aqueous options, as well as phase-change packed bed and Rotating Packed Bed processes for post-combustion CO2 capture. These are high-potential technologies, still in their infancy, with initial evidence pointing to regeneration energy requirements below 2.0 GJ/ton CO2 and considerable reduction of the e...
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 12

 TERMINÉ 
Medication errors occur daily and form a major burden to society. Medication errors often lead to adverse drug reactions, lengthened hospital stays, increased healthcare costs, and in the most severe cases, increased mortality. Medication errors pose a significant risk to the European population. It is estimated that 4,7 million Europeans are harmed by a medication error every year, which amounts ...
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 5

 TERMINÉ 

Resource Efficient Food and dRink for the Entire Supply cHain (REFRESH)

Date du début: 1 juil. 2015, Date de fin: 30 juin 2019,

The overall aim of the REFRESH project is to contribute significantly towards the objective of reducing food waste across the EU by 30% by 2025 (which amounts to between 25 to 40 million tonnes of food not being wasted in 2025[1], worth tens of billions of Euros a year) and maximizing the value from unavoidable food waste and packaging materials. To achieve this ambitious goal, we will adopt a sys...
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 26

 TERMINÉ 

Intelligent Hybrid Thermo-Chemical District Networks (H-DisNet)

Date du début: 1 juin 2016, Date de fin: 31 mai 2019,

The innovative thermo-chemical (TC) network technology of H-DisNet will contribute to next-generation district energy networks. The technology will exploit high chemical potential of absorption processes for loss-free transport and storage of energy potential. It will be applied to form an intelligent district network with thermal, electric and gas networks. This intelligent thermo-chemical distri...
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 7

 TERMINÉ 

Elucidating Pathways of Steatohepatitis (EPoS)

Date du début: 1 mai 2015, Date de fin: 30 avr. 2019,

Strongly associated with the epidemics of obesity and type 2 diabetes mellitus (T2DM) that are testing healthcare systems worldwide, Non-Alcoholic Fatty Liver Disease (NAFLD) is an increasingly common cause of advanced liver disease in the aging population of Europe. NAFLD is a spectrum of hepatic fat accumulation (steatosis); steatosis plus inflammation (non-alcoholic steatohepatitis, NASH); fibr...
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 13

 TERMINÉ 
The aim of OPEUS is to develop a simulation methodology and accompanying modelling tool to evaluate, improve and optimise the energy consumption of rail systems with a particular focus on in-vehicle innovation. The OPEUS concept is based on the need to understand and measure the energy being used by each of the relevant components of the rail system and in particular the vehicle. This includes the...
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 7

 TERMINÉ 
This proposal responds to the first Open Calls issued by the Shift2Rail Joint Undertaking, as part of Shift2Rail Horizon 2020 programme. It specifically addresses the topic S2R-OC-IP5-03-2015: Intelligent freight wagon with predictive maintenance. This topic is complementary with topic S2R-CFM-IP5-02-2015: Start-up activities for Freight Automation. The INNOWAG project will work towards increasing...
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 11

 TERMINÉ 

Living Architecture (LIAR)

Date du début: 1 avr. 2016, Date de fin: 31 mars 2019,

Living Architecture (LIAR) is a modular bioreactor-wall, which is based on the operational principles of microbial fuel cell technology and synthetic ‘consortia’ of microbes. LIAR is conceived as a next-generation selectively-programmable bioreactor and integral component of human dwelling, capable of extracting valuable resources from waste water and air, generation of oxygen and production of p...
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 7