Plus de 40 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Adaptive Bio-electronics for Chronic Cardiorespiratory Disease (CResPace)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,
This consortium will pioneer disruptive technology for bio-electronic medicine to provide much needed therapies for cardiorespiratory and functional neurological disease. The technology implements small neural networks known as central pattern generators (CPG) to deliver fit-and-forget bio-electronic implants that respond to physiological feedback in real time, are safer, simpler, non-invasive, an...
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8
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TERMINÉ
An Integrated European ‘Flagship’ Program Driving Mechanism-based Toxicity Testing and Risk Assessment for the 21st Century (EU-ToxRisk)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2021,
The vision of EU-ToxRisk is to drive a paradigm shift in toxicology towards an animal-free, mechanism-based integrated approach to chemical safety assessment. The project will unite all relevant disciplines and stakeholders to establish: i) pragmatic, solid read-across procedures incorporating mechanistic and toxicokinetic knowledge; and ii) ab initio hazard and risk assessment strategies of chemi...
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43
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TERMINÉ
Combatting Bacterial Resistance in Europe - Molecules against Gram Negative Infections (COMBACTE-MAGNET)
Date du début: 1 janv. 2015, Date de fin: 31 déc. 2021,
Antimicrobial resistance (AMR) is a major global public health threat, and most troublesome is the rapid emergence and dissemination of multidrug resistant (MDR) Enterobacteriaceae, Acinetobacter species and Pseudomonas aeruginosa. There is an unmet medical need to prevent P. aeruginosa infection in critically ill patients and to develop new antibiotics for infections caused by Gram-negative bacte...
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44
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TERMINÉ
NanoPlasmoMechanical Systems (PLASMECS)
Date du début: 1 nov. 2016, Date de fin: 31 oct. 2021,
"With their unparalleled mass and force sensitivities, nanomechanical resonators have the potential to considerably improve existing sensor technology. However, one major obstacle still stands in the way of their practical use: The efficient transduction (actuation & detection) of the vibrational motion of such tiny structures. Localized plasmon resonances "focus" optical fields below the diffract...
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1
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TERMINÉ
Cellular diversity and stress-induced cell-state switches in the mammalian hypothalamus (Secret-Cells)
Date du début: 1 sept. 2016, Date de fin: 31 août 2021,
The hypothalamus is an essential interface among neuroendocrine, autonomic and somatomotor systems, allowing dynamic bodily adaptations to environmental cues via the orchestration of complex physiological processes. Hypothalamic nuclei exhibit unprecedented molecular, structural and functional diversity of neurons, reflecting the breadth of neuroendocrine output. To date, a significant portion of ...
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1
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TERMINÉ
CDK6 in transcription - turning a foe in a friend (CDK6-DrugOpp)
Date du début: 1 sept. 2016, Date de fin: 31 août 2021,
"Translational research aims at applying mechanistic understanding in the development of "precision medicine", which depends on precise diagnostic tools and therapeutic approaches. Cancer therapy is experiencing a switch from non-specific, cytotoxic agents towards molecularly targeted and rationally designed compounds with the promise of greater efficacy and fewer side effects. The two cell-cycle ...
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1
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TERMINÉ
Scattering and tapping on soft-hard-open nuts (SCATAPNUT)
Date du début: 1 sept. 2016, Date de fin: 31 août 2021,
Seeds enclosed in maternal tissue are an important evolutionary plant development as they protect the embryo in many different environments. The protecting coverings are very heterogeneous in structure and origin due to different seed dispersal strategies and environments designed for. The ones having hard outer coverings are commonly called nuts and their shells have recently become of interest f...
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1
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TERMINÉ
Therapeutic approaches to enhance innate immunity against Tumors (TNT-TUMORS)
Date du début: 1 sept. 2016, Date de fin: 31 août 2021,
Recent advances using immune checkpoint inhibitors demonstrate the great potential of immunemodulation in cancer and metastasis treatment. However, the effective treatment of only a subset of patients shows that this is only the start to utilize the power of the immune system to fight cancer. An interesting approach is to harness innate immune cells, such as plasmacytoid dendritic cells (pDCs) and...
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1
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TERMINÉ
MSc European Forestry
Date du début: 1 sept. 2016, Date de fin: 30 août 2021,
Master of Science in European Forestry (MSc EF) is a two-year interdisciplinary programme that provides academic education in the field of sustainable resource management with special emphasis of bio-economy. MSc EF offers a new approach to the markets in forestry and nature management and it connects the increasing number of forest related issues with European dimension at international as well a...
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6
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TERMINÉ
Clinical development and proof of principle testing of new regenerative VEGF-D therapy for cost-effective treatment of refractory anginaA phase II randomized, double-blinded, placebo-controlled study (ReGenHeart)
Date du début: 1 janv. 2017, Date de fin: 30 juin 2021,
Chronic angina pectoris is a debilitating chronic disease, a subgroup of these patients suffers from refractory angina which unfortunately can’t be controlled by medical therapy (angioplasty or surgery). Refractory angina is a substantial burden on the individual and healthcare system, in Europe there are 100,000 new cases per year, annual mortality of these patients is relatively low (
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10
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TERMINÉ
Symbolic Computation and Automated Reasoning for Program Analysis (SYMCAR)
Date du début: 1 avr. 2016, Date de fin: 31 mars 2021,
Individuals, industries, and nations are depending on software and systems using software. Automated approaches are needed to eliminate tedious aspects of software development, helping software developers in dealing with the increasing software complexity. Automatic program analysis aims to discover program properties preventing programmers from introducing errors while making changes and can dras...
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1
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TERMINÉ
Identifying the food cultures of ancient Europe: an interdisciplinary investigation of plant ingredients, culinary transformation and evolution through time (PLANTCULT)
Date du début: 1 avr. 2016, Date de fin: 31 mars 2021,
The project seeks to explore culinary practice among early farming European communities, from the Aegean to Central Europe, spanning the Neolithic through to the Iron Age (7th-1st millennia BC). The project seeks to identify the ‘food cultures’ of prehistoric Europe, and to reconstruct how cultivated and wild plant foods were transformed into dishes exploring their underlying cultural and environm...
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5
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TERMINÉ
Smart and Inclusive Solutions for a Better Life in Urban Districts (SMARTER TOGETHER)
Date du début: 1 févr. 2016, Date de fin: 31 janv. 2021,
SMARTER TOGETHER’s overarching vision is to find the right balance between smart technologies and organizational/ governance dimensions in order to deliver smart and inclusive solutions and to improve citizen’s quality of life.SMARTER TOGETHER gather the European Lighthouse cities Lyon, Munich, Vienna, the Follower cities Santiago de Compostela, Sofia, Venice and Kyiv and Yokohama as observer citi...
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30
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TERMINÉ
Overcoming the Limits of Diffraction with Superresolution Lighting on a Chip (ChipScope)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
The physical laws of diffraction generally limit the spatial resolution of optical systems, being about 200 nm for light in the visible range. Within ChipScope we want to overcome this limit by developing the scientific and technological basis for a completely new approach to optical superresolution, based on semiconductor nano Light Emitting Diode (nanoLED) arrays with individual pixel operation....
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7
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TERMINÉ
Towards enduring mouse resources and services advancing research into human health and disease (INFRAFRONTIER2020)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
The INFRAFRONTIER RI integrates European Mouse Clinics and the European Mouse Mutant Archive with the common goal to ensure access to mouse models for basic research of human health and disease, and to translate this knowledge into therapeutic approaches for the benefit of the European society. The expanded INFRAFRONTIER2020 network, coordinated by the INFRAFRONTIER GmbH, includes 3 SMEs and is st...
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33
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TERMINÉ
Ubiquitous Pharmacogenomics (U-PGx): Making actionable pharmacogenomic data and effective treatment optimization accessible to every European citizen (U-PGx)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,
Pharmacogenomics is the study of genetic variability affecting an individual’s response to a drug. Its use allows personalized medicine and reduction in ‘trial and error’ prescribing leading to more efficacious, safer and cost-effective drug therapy. The U-PGx consortium will investigate a pre-emptive genotyping approach (that is: multiple pharmacogenomic variants are collected prospectively and ...
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16
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TERMINÉ
Scanning probe microscopies for nanoscale fast, tomographic and composition imaging (SPM2.0)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
Advanced Microscopy techniques are widely recognized as one of the pillars onto which the research and manufacture of Nanotechnology based products is sustained. At present, the greatest challenge faced by these techniques is the realization of fast and non-destructive tomographic images with chemical composition sensitivity and with sub-10 nm spatial resolution, in both organic and inorganic mate...
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10
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TERMINÉ
Effect of ALlopurinol in addition to hypothermia for hypoxic-ischemic Brain Injury on Neurocognitive Outcome (ALBINO)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,
Neonatal hypoxic-ischemic encephalopathy (HIE) is a major cause of death or long-term disability in infants born at term in the western world, affecting about 1-4 per 1.000 life births and consequently about 5-20.000 infants per year in Europe.Hypothermic treatment became the only established therapy to improve outcome after perinatal hypoxic-ischemic insults. Despite hypothermia and neonatal inte...
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18
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TERMINÉ
An Artificial Leaf: a photo-electro-catalytic cell from earth-abundant materials for sustainable solar production of CO2-based chemicals and fuels (A-LEAF)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
A novel concept for a photo-electro-catalytic (PEC) cell able to directly convert water and CO2 into fuels and chemicals (CO2 reduction) and oxygen (water oxidation) using exclusively solar energy will be designed, built, validated, and optimized. The cell will be constructed from cheap multifunction photo-electrodes able to transform sun irradiation into an electrochemical potential difference (e...
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15
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TERMINÉ
“In Vivo Click PET Imaging Agents”: Improving clinical companion diagnostics (Click-It)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,
Companion diagnostics are crucial for drug development and disease management with regard to patient selection, therapy planning and monitoring. Nanomedicines such as antibodies have been proven to be optimal disease-targeting agents because they generally exhibit superior target uptake and retention. However, to date, nuclear imaging of nanomedicines has been limited to the use of long-lived isot...
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6
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TERMINÉ
Hybrid optical and optoacoustic endoscope for esophageal tracking. (ESOTRAC)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
More than 450.000 people are diagnosed with esophageal cancer (EC) each-year worldwide and approximately 400.000 die from the disease. Esophageal cancer is the eighth most commonly diagnosed cancer, but it is the sixth leading cause of cancer-related death, with incidence rates steeply rising. Risk factors, including gastroesophageal reflux disease and Barrett’s esophagus, may diagnostically impli...
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9
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TERMINÉ
European Network on Anti-Cancer Immuno-Therapy Improvement by modification of CAR and TCR Interactions and Nanoscale Geometry (EN_ACTI2NG)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
The EN-ACTI2NG program (European Network on Anti-Cancer Immuno-Therapy Improvement by modification of CAR and TCR Interactions and Nanoscale Geometry) emanates from the recent clinical evidence that T cells expressing engineered tumor-specific immune receptors can eradicate certain tumors that do not respond to conventional treatment. To obtain T cells with reactivity to a wider array of tumors an...
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11
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TERMINÉ
From microbial interactions to new-concept biopesticides and biofertilizers (INTERFUTURE)
Date du début: 1 déc. 2016, Date de fin: 30 nov. 2020,
The Directive 2009/128/EC sets rules in EU for the sustainable use of pesticides to reduce the risks and impacts of pesticide use on people's health and the environment. Among the listed actions there is the promotion of low pesticide-input management including non-chemical methods. In parallel several chemical active ingredients have been banned because of toxicity concerns. The result is that gr...
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11
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TERMINÉ
Biowaste derived volatile fatty acid platform for biopolymers, bioactive compounds and chemical building blocks (VOLATILE)
Date du début: 1 déc. 2016, Date de fin: 30 nov. 2020,
VOLATILE aims in the development of an innovative Volatile Fatty Acids Platform for the bioconversion of municipal solid bio-waste fraction and sludgy biowaste from other industries. The platform will be integrated in anaerobic digestion. The volatile fatty acids will be recovered continuously using sophisticated membrane technology and will be provided as feedstock / carbon source for value added...
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21
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TERMINÉ
Applied Public-Private Research enabling OsteoArthritis Clinical Headway (APPROACH)
Date du début: 1 juin 2015, Date de fin: 30 nov. 2020,
The problem: finding the right patient for the right treatmentDespite a large and growing disease burden in osteoarthritis (OA), many pharmaceutical companies have de-emphasized or even abandoned OA drug development due to perceived hurdles. Crucial in this is the lack of appropriate outcome measures that can robustly identify patient benefit from a specific therapy. The lack of specific and sensi...
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25
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TERMINÉ
Multi-modal Optical Diagnostics for Ocular and Neurodegenerative Disease (MOON)
Date du début: 1 nov. 2016, Date de fin: 31 oct. 2020,
The rising life expectancy of EU citizens is creating a dramatic increase in age-related degenerative diseases and associated healthcare costs. The MOON Project (Multi-modal Optical Diagnostics for Ocular and Neurodegenerative Disease) meets this societal challenge by applying photonics to diagnose age-related diseases of the eye and central nervous system. Consistent with the ICT-29-2016: Photoni...
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6
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TERMINÉ
PLATInum group metals Recovery Using Secondary raw materials (PLATIRUS)
Date du début: 1 nov. 2016, Date de fin: 31 oct. 2020,
The PLATIRUS project aims at reducing the European deficit of Platinum Group Metals (PGMs), by upscaling to industrial relevant levels a novel cost-efficient and miniaturised PGMs recovery and raw material production process. The targeted secondary raw materials will be autocatalysts, electronic waste (WEEE) and tailings and slags from nickel and copper smelters, opening-up an important range of a...
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12
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TERMINÉ
EU Pig Innovation Group (Eu PiG)
Date du début: 1 nov. 2016, Date de fin: 31 oct. 2020,
The European Union (EU) is the world’s second biggest producer of pigmeat and is the market’s largest exporter. In order to maintain an economically viable and sustainable pig industry, innovation is a key factor. EU PiG specifically aims to more effectively connect producers with the latest science, husbandry techniques and technologies from within their industry via fellow producers, academics a...
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19
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TERMINÉ
Technology Enabled Adolescent Mental Health (TEAM)
Date du début: 1 nov. 2016, Date de fin: 31 oct. 2020,
There is no health without mental health. 27% of our population are young, and mental health disorders are our leading cause of disability. 50% of mental disorders emerge by 14 yrs, 75% by 24 yrs and, untreated, triple odds of having a mental health disorder in later life. TEAM’s will build a network of expertise and train a new generation of researchers to deliver more effective, affordable and f...
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9
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TERMINÉ
OMT - Optomechanical Technologies (OMT)
Date du début: 1 oct. 2016, Date de fin: 30 sept. 2020,
The proposed project is built on the successful training and research experience of the leading European research groups working in the field of cavity optomechanics. Our ENT unites a total of 14 leading groups in the field, of which two are major industrial players that utilize MEMS and NEMS - Bosch and IBM. The main goal of the project is to exploit optomechanical interactions in views of novel...
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14
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TERMINÉ
An e-infrastructure for software, training and consultancy in simulation and modelling (E-CAM)
Date du début: 1 oct. 2015, Date de fin: 30 sept. 2020,
E-CAM will create, develop and sustain a European infrastructure for computational science applied to simulation and modelling of materials and of biological processes of industrial and societal importance. Building on the already significant network of 15 CECAM centres across Europe and the PRACE initiative, it will create a distributed, sustainable centre for simulation and modelling at and acro...
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18
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TERMINÉ
Multimodal, Functional Bio-Photonic Imaging (FBI)
Date du début: 1 oct. 2016, Date de fin: 30 sept. 2020,
FBI fosters education of ESRs on an emerging, multimodal imaging platform and its translation into clinical and biological applications. In FBI, 15 ESRs are trained at world-leading European academic institutions and companies, thus forming strong interdisciplinary relations between industry, technical sciences and clinical end-users.Optical imaging has huge potential to address unmet clinical nee...
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10
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TERMINÉ
Techniques and Technologies for Effective Wood Procurement (TECH4EFFECT)
Date du début: 1 oct. 2016, Date de fin: 30 sept. 2020,
The project focuses on increasing access to wood resources through more efficient silviculture and a better understanding of the business models governing the procurement of forest operations services. The project further considers increasing efficiency in forest harvesting and collection, and the reduction of soil impact from forest operations, and puts forward ways of making this a measurable an...
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19
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TERMINÉ
Heating and Cooling: Open Source Tool for Mapping and Planning of Energy Systems (HotMaps)
Date du début: 1 oct. 2016, Date de fin: 30 sept. 2020,
HotMaps will develop, demonstrate and disseminate a toolbox to support public authorities, energy agencies and planners in strategic heating and cooling planning on local, regional and national levels, and in-line with EU policies. The toolbox will facilitate the following tasks on a spatially disaggregated level: (1) Mapping heating and cooling energy situation including renewable and waste heat ...
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16
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TERMINÉ
Low energy ELEctron driven chemistry for the advantage of emerging NAno-fabrication methods (ELENA)
Date du début: 1 oct. 2016, Date de fin: 30 sept. 2020,
Chemistry is fundamental to nanotechnology, as chemistry can prepare specifically tailored molecules to serve, in a bottom-up approach, as the building blocks for the fabrication of functional and structured nano-materials. Nanotechnology is the technology of the 21st century with applications from electronics to biotechnology and medicine. The next decade will thus be characterized by an increasi...
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14
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TERMINÉ
Optical imaging of ocular pathology in Alzheimer’s disease (OPTIMALZ)
Date du début: 1 sept. 2015, Date de fin: 31 août 2020,
Novel diagnostic techniques and disease models have the powerful potential to provide new insights into pathological and pathophysiological processes. Ocular manifestations of Alzheimer’s disease (AD) emerge as novel and attractive alternative to investigate disease progression in parallel to the brain. Using the eye as a window to the brain, we propose to develop multi-functional optical coherenc...
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1
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TERMINÉ
Targeted Cell Recruitment During Organogenesis And Regeneration: Glia Makes The Tooth (STEMMING-FROM-NERVE)
Date du début: 1 août 2015, Date de fin: 31 juil. 2020,
Recently we discovered an entirely new phenomenon in developmental biology – targeted recruitment of stem cells from the pervasive peripheral nerves. For example, we demonstrated that majority of melanocytes – our pigment cells, are born from peripheral glial cells. To further extend this far-reaching principle we will use tooth development as a model. Current opinion holds that sensory innervatio...
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1
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TERMINÉ
The artificial pancreas in children aged 1 to 7 years with type 1 diabetes (KidsAP)
Date du début: 1 janv. 2017, Date de fin: 30 juin 2020,
TYPE 1 DIABETES is one of the most COMMON CHRONIC diseases in children with a RAPID increase in number of cases particularly in young children. Type 1 diabetes is associated with LIFE-LONG dependency on insulin administration. POOR glucose control leads to diabetes COMPLICATIONS, e.g. eye, heart, kidney disease, including BRAIN changes in young children. Episodes of VERY LOW glucose levels may be ...
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14
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TERMINÉ
Mechanisms of Auxin-dependent Signaling in the Endoplasmic Reticulum (AuxinER)
Date du début: 1 juin 2015, Date de fin: 31 mai 2020,
The phytohormone auxin has profound importance for plant development. The extracellular AUXIN BINDING PROTEIN1 (ABP1) and the nuclear AUXIN F-BOX PROTEINs (TIR1/AFBs) auxin receptors perceive fast, non-genomic and slow, genomic auxin responses, respectively. Despite the fact that ABP1 mainly localizes to the endoplasmic reticulum (ER), until now it has been proposed to be active only in the extrac...
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1
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TERMINÉ
European Joint Programme for the Integration of Radiation Protection Research (CONCERT)
Date du début: 1 juin 2015, Date de fin: 31 mai 2020,
The proposed European Concerted Programme on Radiation Protection Research (acronym: CONCERT) aims to contribute to the sustainable integration of European and national research programmes in radiation protection. It will do so by focusing resources and efforts in five key directions:• Bring together the elements of the European scientific communities in the fields of radiation effects and risks, ...
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