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Plus de 40 projets européens trouvés

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 TERMINÉ 

Transcranial brain stimulation as innovative therapy for chronic pediatric neuropsychiatric disorder – STIPED (STIPED)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Due to lack of targeted interventions, compliance issues, insufficient effect sizes and a high non-responder rate to currently available interventions, there is an urgent need to develop innovative and new interventions for chronic paediatric neuropsychiatric disorders, such as Attention-Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD). Transcranial direct current stimulati...
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 12

 TERMINÉ 

Releasing the full potential of Instruct to expand and consolidate infrastructure services for integrated structural life science research (INSTRUCT-ULTRA)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Instruct-Ultra aims to advance the scope and efficiency of implementation of Instruct and consolidate the foundations for long-term sustainability. This will be achieved through specific objectives: expand Instruct membership to new Member States and increase global links; engage new user communities; improve efficiencies in service delivery; improve data capture and management; adjust the scale a...
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 19

 TERMINÉ 

Implementation of cost-optimized childhood vision and hearing screening programmes in middle-income countries in Europe (EUSCREEN)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Screening for vision and hearing disorders in children has shown to be highly effective. EU-directive 16620/11 invites EU-member states to give priority to such screening programmes. Early detection and treatment of a lazy eye (prevalence 3%) prevents lifelong visual impairment. Early detection and treatment of hearing impairment (prevalence 0.15%) prevents delayed speech and language development....
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 10

 TERMINÉ 

Readiness of ICOS for Necessities of integrated Global Observations (RINGO)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

The proposed project “Readiness of ICOS for Necessities of integrated Global Observations” (RINGO) aims to further development of ICOS RI and ICOS ERIC and foster its sustainability. The challenges are to further develop the readiness of ICOS RI along five principal objectives: 1. Scientific readiness. To support the further consolidation of the observational networks and enhance their quality. Th...
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 26

 TERMINÉ 

Cell-cell interactions at the neurovascular interface (NEUROVESSEL)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

The coordinated orchestration of cell movements is a vital process for assembling functional structures. In recent years we have learned a simplifying lesson: organ development is governed by a limited set of conserved cell-to-cell communication signaling pathways repeatedly used in different contexts. Particularly fascinating is the parallelism between the vascular and nervous systems. My lab has...
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 1

 TERMINÉ 

Comorbid Conditions of Attention deficit / hyperactivity disorder (CoCA)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

Understanding mechanisms underlying comorbid disorders poses a challenge for developing precision medicine tools. Psychiatric disorders are highly comorbid, and are among the last areas of medicine, where classification is driven by phenomenology rather than pathophysiology. We will study comorbidity between the most frequent psychiatric conditions, ADHD, mood/anxiety, and substance use disorders,...
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 17

 TERMINÉ 

Endothelial long non-coding RNAs (Angiolnc)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

Endothelial cells comprise the inner cellular cover of the vasculature, which delivers metabolites and oxygen to the tissue. Dysfunction of endothelial cells as it occurs during aging or metabolic syndromes can result in atherosclerosis, which can lead to myocardial infarction or stroke, whereas pathological angiogenesis contributes to tumor growth and diabetic retinopathy. Thus, endothelial cells...
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 1

 TERMINÉ 

Molecular Tools for Nucleic Acid Manipulation for Biological Intervention (MMBio)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

MMbio will bridge the classically separate disciplines of Chemistry and Biology by assembling leading experts from academia and non-academic partners (industry, technology transfer & science communication) to bring about systems designed to interfere therapeutically with gene expression in living cells. Expertise in nucleic acid synthesis, its molecular recognition and chemical reactivity is combi...
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 13

 TERMINÉ 

Model-Based Construction And Optimisation Of Versatile Chassis Yeast Strains For Production Of Valuable Lipid And Aromatic Compounds (CHASSY)

Date du début: 1 déc. 2016, Date de fin: 30 nov. 2020,

CHASSY will unlock the full potential of the yeasts Saccharomyces cerevisiae, Yarrowia lipolytica and Kluyveromyces marxianus as cell factories for production of high value compounds which have applications in the cosmetic, nutraceutical and white biotechnology sectors. Current cell factory strains for these classes of product are restricted to proof-of-principle levels because of limited precurso...
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 10

 TERMINÉ 

Imaging the Event Horizon of Black Holes (BLACKHOLECAM)

Date du début: 1 oct. 2014, Date de fin: 30 sept. 2020,

Gravity is successfully described by Einstein’s theory of general relativity (GR), governing the structure of our entire universe. Yet it remains the least understood of all forces in nature, resisting unification with quantum physics. One of the most fundamental predictions of GR are black holes (BHs). Their defining feature is the event horizon, the surface that light cannot escape and where tim...
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 6

 TERMINÉ 

Unraveling Principles of PDZ-mediated Cell Signaling (PDZnet)

Date du début: 1 sept. 2016, Date de fin: 31 août 2020,

PDZnet will create an innovative European PhD training network focusing on unraveling PDZ domain-mediated signaling networks. The emphasis will be on signaling nodes essential for the development of cancer and diseases of the nervous system, conditions that affect millions of Europeans and are major societal challenges. PDZ domains are protein and lipid recognizing modules that play a central role...
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 10

 TERMINÉ 

Pharmaceutical Education And Research with Regulatory Links: Innovative drug development strategies and regulatory tools tailored to facilitate earlier access to medicines (PEARRL)

Date du début: 1 mai 2016, Date de fin: 30 avr. 2020,

The European Pharma industry is a major contributor to EU well-being, both in public health and economic (sales >200 billion €/year) terms. To maintain global leadership, it must respond to challenges from low-cost producers e.g. China by bringing new drug molecules to market in a streamlined, cost-effective manner. This strategy is underscored by recent initiatives of European regulators to exped...
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 9

 TERMINÉ 

Non-coding RNA in Vascular Ageing (NOVA)

Date du début: 1 avr. 2015, Date de fin: 31 mars 2020,

Life expectancy in the European Union is rising and the prevalence of age-induced cardiovascular disease increases concomitantly. Endothelial dysfunction is a hallmark of aging in the vasculature and is the underlying cause of many cardiovascular disorders, like hypertension, acute myocardial infarction and stroke. This proposal aims to better understand the molecular mechanisms behind aging that ...
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 1

 TERMINÉ 

Convergence of Electronics and Photonics Technologies for Enabling Terahertz Applications (CELTA)

Date du début: 1 mars 2016, Date de fin: 29 févr. 2020,

CELTA: Convergence of Electronics and Photonics Technologies for Enabling Terahertz Applications aims to produce the next generation of researchers who will enable Europe to take a leading role in the multidisciplinary area of utilizing Terahertz technology for applications involving components and complete systems for sensing, instrumentation, imaging, spectroscopy, and communications. All these ...
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 13

 TERMINÉ 

Angular studies of photoelectrons in innovative research environments (ASPIRE)

Date du début: 1 mars 2016, Date de fin: 29 févr. 2020,

In the ASPIRE project, whose academic and industrial beneficiaries are world leading in their complementary fields of expertise, the overarching research goal is the measurement of photoelectron angular distributions (PADs) in the “molecular frame” (MF) of systems of biological relevance. These MF-PADs can be interpreted as electron diffraction patterns, achieved by “illuminating the molecule from...
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 9

 TERMINÉ 

Solar Energy to Biomass - Optimisation of light energy conversion in plants and microalgae (SE2B)

Date du début: 1 mars 2016, Date de fin: 29 févr. 2020,

In the face of the increasing global consumption of fossil resources, photosynthetic organisms offer an attractive alternative that could meet our rising future needs as clean, renewable, sources of energy and for the production of fine chemicals. Key to the efficient exploitation of these organisms is to optimise the conversion of Solar Energy into Biomass (SE2B). The SE2B network deals with this...
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 12

 TERMINÉ 

Production and characterization of endocrine cells derived from human pancreas organoids for the cell-based therapy of type 1 diabetes (LSFM4LIFE)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

Self-renew and multilineage potential characterize stem cells. We have recently described that pancreas progenitor cells extracted from adult donors can be expanded long-term in vitro into 3D structures, which we have termed organoids. Pancreas organoids reproduce in vitro all the features of pancreas ductal epithelia, and have a limitless expansion potential. Thus, pancreas organoids promise t...
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 7

 TERMINÉ 

Privacy and Usabiliy (Privacy.Us)

Date du début: 1 déc. 2015, Date de fin: 30 nov. 2019,

With the rapid accumulation and processing of personal data by numerous organizations, it is of paramount importance to protect people from adverse uses of their data, while allowing them to enjoy the benefits the use of these data can possibly provide. This is the question of protecting citizens’ privacy, while enabling them to make informed decisions regarding their actions with privacy implicat...
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 10

 TERMINÉ 

Deciphering the Metabolism of Haematological Cancers (HaemMetabolome)

Date du début: 1 oct. 2015, Date de fin: 30 sept. 2019,

It has long been realised that metabolism is central to cellular development, proliferation and homeostasis. Collectively, aberrations in metabolism are now recognised as a major hallmark of cancer, opening new avenues for personalised medicine. As haematological malignancies are multi-factorial diseases, our main emphasis will be on the integration of biomedical multi-omics data and computational...
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 4

 TERMINÉ 

Endoplasmic Reticulum Stress in Health and Disease (TRAIN-ERS)

Date du début: 1 oct. 2015, Date de fin: 30 sept. 2019,

Endoplasmic reticulum (ER) stress is emerging as a common feature in the pathology of numerous diseases including cancer, neurodegenerative disorders, metabolic syndromes and inflammatory diseases. Thus ER stress represents a potential therapeutic intervention point to be exploited to develop novel therapies, diagnostic tools and markers for these diseases. However, exploitation is hampered by the...
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 12

 TERMINÉ 

Infrastructure for NMR, EM and X-rays for translational research (iNEXT)

Date du début: 1 sept. 2015, Date de fin: 31 août 2019,

Structural biology provides insight into the molecular architecture of cells up to atomic resolution, revealing the biological mechanisms that are fundamental to life. It is thus key to many innovations in chemistry, biotechnology and medicine such as engineered enzymes, new potent drugs, innovative vaccines and novel biomaterials.iNEXT (infrastructure for NMR, EM and X-rays for Translational rese...
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 23

 TERMINÉ 

Brain barriers training (BtRAIN)

Date du début: 1 sept. 2015, Date de fin: 31 août 2019,

The brain barriers function to protect the central nervous system (CNS) from neurotoxic compounds. By the same traits they unfortunately block delivery of drugs to the CNS thus hindering proper diagnosis and effective treatment of neurological disorders including Alzheimer’s disease and multiple sclerosis. The unusual complexity of the brain barriers has severely hampered progress in the market of...
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 11

 TERMINÉ 

Corroding the social? An empirical evaluation of the relationship between unemployment and social stratification in OECD countries (CORRODE)

Date du début: 1 sept. 2014, Date de fin: 31 août 2019,

"The proposal describes a project to deliver a comprehensive evaluation of the relationship between unemployment and social stratification in Europe and North America. The project’s core goal is to provide empirical estimates of the causal impact of unemployment on four critical domains of social life, namely household incomes, demographic behaviour, educational attainment, as well as social integ...
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 1

 TERMINÉ 

Language-Processing by Overlapping Predictions: A Predictive Coding Approach (L-POP)

Date du début: 1 juil. 2014, Date de fin: 30 juin 2019,

"This project aims at elucidating fundamental neural computations underlying language processing. While we have gained enormous insights into the localization of language in the brain and the temporal sequence of language processes (e.g., syntactic vs. semantic), we know very little about the actual computations underlying language processing. I propose that the framework of predictive coding can ...
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 1

 TERMINÉ 

Intra Erythrocyte Dexamethasone in the treatment of Ataxia Telangiectasia (IEDAT)

Date du début: 1 janv. 2016, Date de fin: 30 avr. 2019,

The main objective of the project is to provide a treatment of the neurological symptoms of patients with Ataxia Telangiectasia (AT), a rare progressively disabling and life-shortening genetic disease for which no therapy is currently available. To achieve this, a pivotal Phase III study will be conducted, to allow regulatory filing to obtain market authorization in EU and USA by 2019. EryDex is a...
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 7

 TERMINÉ 

MYRRHA Research and Transmutation Endeavour (MYRTE)

Date du début: 1 avr. 2015, Date de fin: 31 mars 2019,

The Strategic Research Agenda of the EU Sustainable Nuclear Energy Technical platform requires new large infrastructures for its successful deployment. MYRRHA has been identified as a long term supporting research facility for all ESNII systems and as such put in the high-priority list of ESFRI. The goal of MYRTE is to perform the necessary research in order to demonstrate the feasibility of trans...
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 28

 TERMINÉ 

Neutron cAptUres consTraIning steLlar nUcleosynthesiS (NAUTILUS)

Date du début: 1 avr. 2014, Date de fin: 31 mars 2019,

"NAUTILUS will investigate the nucleosynthesis of the chemical elements during the evolution of stars, which is the basis for understanding the chemical history of the Universe. The vast majority of the elements heavier than iron are produced by neutron capture reactions. The precise knowledge of the involved neutron capture cross sections for certain isotopes sets tight limits for stellar paramet...
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 1

 TERMINÉ 

Policies Supporting Young People in their Life Course. A Comparative Perspective of Lifelong Learning and Inclusion in Education and Work in Europe (YOUNG_ADULLLT)

Date du début: 1 mars 2016, Date de fin: 28 févr. 2019,

Most European Lifelong Learning (LLL) policies have been designed to create economic growth and, at the same time, guarantee social inclusion (EC 2010). First, we will study how different LLL policies are compatible with each other in terms of their orientations and objectives and how each policy considers the needs of ‘young adults’. Second, we will research the intended and unintended effects of...
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 15

 TERMINÉ 

analyse Soluble + Membrane complexes with Improved LILBID Experiments (a SMILE)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,

Crucial processes within cells depend on specific non-covalent interactions which mediate the assembly of proteins and other biomolecules. Deriving structural information to understand the function of these complex systems is the primary goal of Structural Biology.In this application, the recently developed LILBID method (Laser Induced Liquid Bead Ion Desorption) will be optimized for investigatio...
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 1

 TERMINÉ 

Clinical Translation of Patient-Specific Planning and Conduction of FUS Treatment in Moving Organs (TRANS-FUSIMO)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2018,

MR-guided Focused Ultrasound Surgery (MRgFUS) combines high intensity focused ultrasound for thermal ablation of diseased tissue with MR imaging to visualise the tumour and surrounding anatomy and to provide MR thermal feedback.However, MRgFUS treatment of the liver and other abdominal organs present tremendous technological challenges, including motion due to breathing and shielding of the target...
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 11

 TERMINÉ 

EUROPOL

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2018,

NMR and MRI play unique roles in contemporary Science, from Physics, Chemistry and Biology, to clinical research and diagnosis. Despite its irreplaceable role, further progress in NMR and MRI is hampered by sensitivities that are much lower than those of alternatives such as mass-spec, or PET. The prospects of solving this problem by “bigger machines” are uncertain and of poor return, given the hi...
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 12

 TERMINÉ 

Brachiopods As SEnsitive tracers of gLobal marINe Environment: Insights from alkaline, alkaline Earth metal, and metalloid trace element ratios and isotope systems (BASE-LiNE Earth)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2018,

"Data on seawater composition since the start of the Phanerozoic eon ~540 million years ago provide essential information for understanding long-term chemical processes of socio-economic dimension like the evolution of life, land-ocean interaction, atmospheric chemistry, ecosystem adaptation to climate change, oceanic trace metal cycling, and for applied geological processes like the formation of ...
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 14

 TERMINÉ 

Mastering skills in the training Network for attention deficit hyperactivity and autism spectrum Disorders (MiND)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2018,

Attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorders (ASD) are frequent, chronic and highly heritable neurodevelopmental disorders. Despite their societal importance, progress in understanding disease biology has been slow and no curative treatment options are available.The pan-European training network MiND aims to educate a new generation of researchers in the field of n...
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 12

 TERMINÉ 

European Digital Online-Game for Intercultural Learning and Translanguaging

Date du début: 1 déc. 2016, Date de fin: 30 nov. 2018,

The increasing number of refugees and migrants within EU countries forces all stakeholders involved in language education and integration to rethink traditional concepts of language education. Successful integration of migrants, especially in participatory processes, strongly depends on learning local foreign languages and intercultural competencies, without neglecting heritage languages and cultu...
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 6

 TERMINÉ 

Understanding chronic pain and new druggable targets: Focus on glial-opioid receptor interface (GLORIA)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2018,

"Chronic pain is prevalent and it causes decreased quality of life and significant costs to the society in terms of lost working capacity. Currently available analgesics are either not effective enough or patients cannot take them due to adverse effects. Non-steroidal anti-inflammatory drugs are a major cause of drug-related morbidity and mortality. Opioids can cause tolerance and addiction when u...
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 5

 TERMINÉ 

Aggression subtyping for improved insight and treatment innovation in psychiatric disorders (AGGRESSOTYPE)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2018,

Aggression is a basic physiological trait with important roles throughout evolution, both in defence and predation. When expressed in humans in the wrong context, aggression leads to maladjustment, social impairment and crime. Despite this, knowledge about aggression aetiology is limited and current treatment strategies are insufficient. Contingent to a subdivision into impulsive and instrumental ...
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 27

 TERMINÉ 

Secure Cloud Identity Wallet (CREDENTIAL)

Date du début: 1 oct. 2015, Date de fin: 30 sept. 2018,

With increasing mobility and Internet usage, the demand for digital services increases and has reached critical and high assurance domains like e-Government, e-Health and e-Business. Those domains have high security and privacy requirements and hence will be harnessed with various novel mechanisms for secure access. Approaches for handling the resulting variety of authentication and authorisation ...
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 12

 TERMINÉ 

European University Tandem

Date du début: 1 oct. 2015, Date de fin: 31 mars 2018,

European University Tandem Since the project start on 1 October 2015, all project outputs have been realized largely within the envisaged time frames. Until the end of August 2016, two project meetings took place, the kick-off meeting in Frankfurt (Oct 2015) and the second meeting in Barcelona (March 2016). The third meeting in Florence in coming up in September 2016. The first 6 months, between t...
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 7

 TERMINÉ 

Smart Nano-objects for Alteration of Lipid-bilayers (SNAL)

Date du début: 1 avr. 2014, Date de fin: 31 mars 2018,

"SNAL is a multidisciplinary programme specially designed to provide scientific and transferable skill training and career development for early stage researchers and experienced researchers in membrane research. Working in a multidisciplinary network will give the researchers a broad perspective on their research field as well as the basic ability of pursuing a research project from basic science...
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 10

 TERMINÉ 

Promoting EU-funded projects of inclusive, innovative and reflective societies (DANDELION)

Date du début: 1 avr. 2016, Date de fin: 31 mars 2018,

Dandelion will promote the work done by inclusive, innovative and reflective societies’ projects on a local, regional and European level by developing and implementing a series of innovative and exciting communications activities aiming to inform, educate and entertain a wide cross section of the European population, policy makers, academics and media. By placing European economic and financial re...
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 7