Plus de 40 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Towards enduring mouse resources and services advancing research into human health and disease (INFRAFRONTIER2020)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
The INFRAFRONTIER RI integrates European Mouse Clinics and the European Mouse Mutant Archive with the common goal to ensure access to mouse models for basic research of human health and disease, and to translate this knowledge into therapeutic approaches for the benefit of the European society. The expanded INFRAFRONTIER2020 network, coordinated by the INFRAFRONTIER GmbH, includes 3 SMEs and is st...
Voir le projet
33
Participants partenaires
TERMINÉ
iABC Programme (IABC PROGRAMME)
Date du début: 1 août 2015, Date de fin: 31 juil. 2020,
Cystic Fibrosis (CF) is a common fatal inherited disease with a frequency of 1 in 2500 live births, affecting approximately 36,000 (0.737/10,000) people in the EU. Chronic bacterial pulmonary infection leading to an irreversible decline in lung structure and function is the main cause of mortality and morbidity in patients with CF, with more than 95% of deaths due to respiratory failure. Pseudomon...
Voir le projet
21
Participants partenaires
TERMINÉ
HARMONIzation and integrative analysis of regional, national and international Cohorts on primary Sjögren’s Syndrome (pSS) towards improved stratification, treatment and health policy making (HarmonicSS)
Date du début: 1 janv. 2017, Date de fin: 30 juin 2020,
HarmonicSS vision is to create an International Network and Alliance of partners and cohorts, entrusted with the mission of addressing the unmet needs in primary Sjogren Syndrome; working together to create and maintain a platform with open standards and tools, designed to enable secure storage, governance, analytics, access control and controlled sharing of information at multiple levels along wi...
Voir le projet
39
Participants partenaires
TERMINÉ
Personalized Nanomedicines for Leukemia Patients (PNANOMED)
Date du début: 1 juil. 2015, Date de fin: 30 juin 2020,
Acute myeloid leukemia (AML) remains a devastating disease, while progress in genetic characterization and nanomedical approaches promise a new era of individualized treatments. To prioritize genetic aberrations in AML for therapeutic targeting and to develop a pipeline for personalized nanomedicines I will i) establish a biobank of transplantable primary human AML xenotransplants, ii) fully chara...
Voir le projet
1
Participant partenaire
TERMINÉ
Exploring selected long non-coding RNAs as diagnostics and therapeutic targets for heart failure (LONGHEART)
Date du début: 1 juin 2015, Date de fin: 31 mai 2020,
Despite clinical advances, diseases of the cardiovascular system are the most common cause of morbidity and mortality in the EU with currently 50 million people suffering from heart failure. These important challenges call for a better understanding of underlying mechanisms to enable development of innovative, effective diagnostic and therapeutic strategies for heart failure. Cardiac stress such a...
Voir le projet
1
Participant partenaire
TERMINÉ
Training network providing cutting-EDGE knowlEDGE on Herpes Virology and Immunology (EDGE)
Date du début: 1 mai 2016, Date de fin: 30 avr. 2020,
Herpesviruses are widely spread, and cause life-long infections. Most individuals carry multiple herpesviruses, which can cause severe diseases, especially in children, immunocompromised individuals, and elderly. There are currently no safe vaccines against herpesvirus infections and current treatments are not satisfactory. With new insights into the molecular basis for diseases caused by immunode...
Voir le projet
9
Participants partenaires
TERMINÉ
Synergy-based Open-source Foundations and Technologies for Prosthetics and RehabilitatiOn (SoftPro)
Date du début: 1 mars 2016, Date de fin: 29 févr. 2020,
Although much has been done for developing technologies to bear upon problems of individuals with sensorimotor impairments, the impact of robotic aids on people with real needs in the real world is still very limited. Our main goal is to increase the cumulative benefits of assistive robotic technologies to society by enhancing their effectiveness AND the number of beneficiaries. The challenge is ...
Voir le projet
13
Participants partenaires
TERMINÉ
Zoonotic Anticipation and Preparedness Initiative (ZAPI)
Date du début: 1 mars 2015, Date de fin: 29 févr. 2020,
Emerging infectious diseases are occurring at increasing frequency in Europe and other regions of the world, having profound impacts on public and/or veterinary health as well as disruptive effects on sector, regional or even global economy. The predominantly zoonotic nature of emerging pathogens calls for a One Health approach uniting the human medical and veterinary fields, dedicated to swiftly ...
Voir le projet
21
Participants partenaires
TERMINÉ
Massive InteGRATion of power Electronic devices (MIGRATE)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,
By 2020, several areas of the HVAC pan-European transmission system will be operated with extremely high penetrations of Power Electronics(PE)-interfaced generators, thus becoming the only generating units for some periods of the day or of the year – due to renewable (wind, solar) electricity. This will result in i) growing dynamic stability issues for the power system (possibly a new major barrie...
Voir le projet
24
Participants partenaires
TERMINÉ
DevelopIng Genetic medicines for Severe Combined Immunodeficiency (SCID) (SCIDNET)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,
Severe combined immunodeficiency (SCID) is a devastating rare disorder of immune system development. Affected infants are born without functional immune systems and die within the first year of life unless effective treatment is given. Treatment options are limited to allogeneic haematopoietic stem cell transplantation and autologous stem cell gene therapy. Over the last 15 years, gene therapy for...
Voir le projet
13
Participants partenaires
TERMINÉ
Tools and TECHNOlogies for Breakthrough in hEArt Therapies (TECHNOBEAT)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,
Cardiovascular diseases including myocardial infarction (MI), which entails the irreversible loss of heart muscle tissue, constitute a major socio-economic burden in global healthcare. With whole organ transplantation as the only treatment option for end-stage heart failure, MI patients could particularly benefit from advanced cell therapies aimed at the functional reconstitution of damaged hearts...
Voir le projet
8
Participants partenaires
TERMINÉ
COllaborative Management Platform for detection and Analyses of (Re-)emerging and foodborne outbreaks in Europe (COMPARE)
Date du début: 1 déc. 2014, Date de fin: 30 nov. 2019,
COMPARE aims to harness the rapid advances in molecular technology to improve identification and mitigation of emerging infectious diseases and foodborne outbreaks. To this purpose COMPARE will establish a “One serves all” analytical framework and data exchange platform that will allow real time analysis and interpretation of sequence-based pathogen data in combination with associated data (e.g. c...
Voir le projet
32
Participants partenaires
TERMINÉ
NUCLEUS - New Understanding of Communication, Learning and Engagement in Universities and Scientific Institutions (NUCLEUS)
Date du début: 1 sept. 2015, Date de fin: 31 août 2019,
NUCLEUS develops, supports and implements inclusive and sustainable approaches to Responsible Research and Innovation within the governance and culture of research organisations in Europe. A major goal of the transdisciplinary project will be to stimulate research and innovation which continuously reflects and responds to societal needs.In order to achieve a multifaceted and cross-cultural New Und...
Voir le projet
24
Participants partenaires
TERMINÉ
SoBigData Research Infrastructure (SoBigData)
Date du début: 1 sept. 2015, Date de fin: 31 août 2019,
One of the most pressing and fascinating challenges scientists face today, is understanding the complexity of our globally interconnected society. The big data arising from the digital breadcrumbs of human activities promise to let us scrutinize the ground truth of individual and collective behaviour at an unprecedented detail and scale. There is an urgent need to harness these opportunities for s...
Voir le projet
12
Participants partenaires
TERMINÉ
Using marine mammals for making science education and science careers attractive for young people (Marine Mammals)
Date du début: 1 sept. 2016, Date de fin: 31 août 2019,
The Marine Mammals proposes to create a European consortium of education and research institutions, alongside small to medium enterprises, to promote STEM subjects and students’ interest in science careers. All project partners are internationally renowned experts in their field of work. Together with teachers and educational scientists they will form expert groups who will develop teacher trainin...
Voir le projet
10
Participants partenaires
TERMINÉ
Development and disease of the renal tract (RENALTRACT)
Date du début: 1 juin 2015, Date de fin: 31 mai 2019,
The renal tract (kidneys, the ureters, bladder) is a complex organ system crucial for maintaining the body homeostasis. This organ system arises from different precursor pools through a complex program of patterning, differentiation and morphogenesis in embryonic development. Alteration of this program leads to renal tract malformations (RTM) that are incompatible with a healthy life. While some o...
Voir le projet
8
Participants partenaires
TERMINÉ
Aortic Valve Replacement using Individualised Regenerative Allografts: Bridging the Therapeutic Gap (ARISE)
Date du début: 1 janv. 2015, Date de fin: 31 mars 2019,
65,000 aortic valve replacements (AVR) are performed in Europe each year to treat acquired and congenital aortic valve diseases. In affected patients, mortality without AVR is extremely high and 50 % die within 2 years. Current AVR options are, however, limited for young patients - especially female patients - and those unwilling to accept life-long medical anticoagulation with its inherent risks....
Voir le projet
9
Participants partenaires
TERMINÉ
Molecular Reclassification to Find Clinically Useful Biomarkers for Systemic Autoimmune Diseases (PRECISESADS)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,
We concur to the IMI on “Reclassification of SLE, connective tissue diseases and RA” call by presenting a proposal aimed at using the power of OMICs, and bioinformatics to identify new classifications for diseases known to share common pathophysiological mechanisms. Such knowledge has not been applied to individual patients, depriving them from potential benefits in terms of the use of new therape...
Voir le projet
30
Participants partenaires
TERMINÉ
Heart OMics in AGEing (HOMAGE)
Date du début: 1 févr. 2013, Date de fin: 31 janv. 2019,
As more people survive into old age, the prevalence of heart failure (HF), one of the most common and debilitating diseases in older people, will rise still further. Delaying or preventing HF will have great benefit to those at personal risk, their families, society and the economy. HOMAGE aims to provide a biomarker (BM) approach that will a) help identify i. patients at high risk of developing ...
Voir le projet
22
Participants partenaires
TERMINÉ
Development of Selective Carbohydrate Immunomodulators Targeting C-type Lectin Receptors on Antigen Presenting Cells (IMMUNOSHAPE)
Date du début: 1 janv. 2015, Date de fin: 31 déc. 2018,
IMMUNOSHAPE aims at training a new generation of scientists that will be capable of combining state of the art synthesis and screening technology to develop new lead structures for highly selective glycan based multivalent immunotherapeutics for the treatment of cancer, autoimmune diseases and allergy. To this end, we have set up a training program in a unique academic-industrial environment that ...
Voir le projet
17
Participants partenaires
TERMINÉ
Ecology from Farm to Fork Of microbial drug Resistance and Transmission (EFFORT)
Date du début: 1 déc. 2013, Date de fin: 30 nov. 2018,
EFFORT studies the complex epidemiology and ecology of antimicrobial resistance and the interactions between bacterial communities, commensals and pathogens in animals, the food chain and the environment.This will be conducted by a combination of epidemiological and ecological studies using newly developed molecular and bio-informatics technologies. EFFORT will include an exposure assessment of hu...
Voir le projet
21
Participants partenaires
TERMINÉ
Targets and biomarkers for antiepileptogenesis (EPITARGET)
Date du début: 1 nov. 2013, Date de fin: 31 oct. 2018,
Epilepsy is a devastating condition affecting over 50 million people worldwide. This multidisciplinary project is focused on the process leading to epilepsy, epileptogenesis, in adults. Our main hypothesis is that there are combinations of various causes, acting in parallel and/or in succession, that lead to epileptogenesis and development of seizures. Our central premise and vision is that a comb...
Voir le projet
20
Participants partenaires
TERMINÉ
Dobutamine for NEOnatal CIRCulatory failure defined by novel biomarkers (NEO-CIRC)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2018,
Dobutamine and adrenaline are widely used as second line therapy for systemic hypotension in infants. Dopamine is currently the most widely used first line drug. In neonates, sustained hypotension may, and impaired organ perfusion will, cause brain injury and poor neurodevelopmental outcomes. All three catecholamines are currently used off-label and have different modes of action which may result ...
Voir le projet
20
Participants partenaires
TERMINÉ
Project for higher education student and staff mobility between Programme Countries and Partner Countries
Date du début: 1 juin 2016, Date de fin: 31 juil. 2018,
This is a project for higher education student and staff mobility between Programme Countries and Partner Countries. Please consult the website of the organisation to obtain additional details.
Voir le projet
1
Participant partenaire
TERMINÉ
Higher education student and staff mobility project
Date du début: 1 juin 2016, Date de fin: 31 mai 2018,
This is a higher education student and staff mobility project, please consult the website of the organisation to obtain additional details.
Voir le projet
1
Participant partenaire
TERMINÉ
Higher education student and staff mobility project
Date du début: 1 juin 2016, Date de fin: 31 mai 2018,
This is a higher education student and staff mobility project, please consult the website of the organisation to obtain additional details.
Voir le projet
1
Participant partenaire
TERMINÉ
Higher education student and staff mobility project
Date du début: 1 juin 2016, Date de fin: 31 mai 2018,
This is a higher education student and staff mobility project, please consult the website of the organisation to obtain additional details.
Voir le projet
1
Participant partenaire
TERMINÉ
Higher education student and staff mobility project
Date du début: 1 juin 2016, Date de fin: 31 mai 2018,
This is a higher education student and staff mobility project, please consult the website of the organisation to obtain additional details.
Voir le projet
1
Participant partenaire
TERMINÉ
Europa Mobilität in der Ausbildung mit Erasmus über Bildungsakademie Pflege MHH
Date du début: 1 juin 2016, Date de fin: 31 mai 2018,
The educational academy Nursing (BAP) is an autonomous vocational training´s department in the framework of the training academy of the Medical University Hanover, traditionally called MHH. The nursing school trains 200 students, the school for OTA/ATA 150. The MHH has in addition another 257 apprenticeships in varied health care professions. We have achieved till 2014 to send over 100 students, i...
Voir le projet
5
Participants partenaires
TERMINÉ
FUEL FLEXIBLE, NEAR -ZERO EMISSIONS, ADAPTIVE PERFORMANCE MARINE ENGINE (HERCULES-2)
Date du début: 1 mai 2015, Date de fin: 30 avr. 2018,
The project HERCULES-2 is targeting at a fuel-flexible large marine engine, optimally adaptive to its operating environment. The objectives of the HERCULES-2 project are associated to 4 areas of engine integrated R&D:• Improving fuel flexibility for seamless switching between different fuel types, including non-conventional fuels.• Formulating new materials to support high temperature component ap...
Voir le projet
33
Participants partenaires
TERMINÉ
Safety CaUsation, Benefits and Efficiency (SafetyCube)
Date du début: 1 mai 2015, Date de fin: 30 avr. 2018,
The objective of SafetyCube is to develop an innovative road safety Decision Support System (DSS) that will enable policy-makers and stakeholders to select and implement the most appropriate strategies, measures and cost-effective approaches to reduce casualties of all road user types and all severities.At the core of the project will be a novel and comprehensive analysis of accident causation fac...
Voir le projet
18
Participants partenaires
TERMINÉ
GMP Two Year Safety Testing (G-TwYST)
Date du début: 21 avr. 2014, Date de fin: 20 avr. 2018,
G-TwYST will execute rat feeding trials with GM maize NK 603 based on OECD Test Guidelines and according to EFSA considerations. In the case of maize NK603 two 90-day and a combined 2-year chronic toxicity/carcinogenicity study will be performed. By combining the results of the G-TwYST project with those of the GRACE project (90-day and 1-year study with maize MON810) it will be possible for the ...
Voir le projet
9
Participants partenaires
TERMINÉ
Lymph node homing of immune cells via afferent lymphatics – mechanisms and immune response (LYMPHATICS-HOMING)
Date du début: 1 avr. 2013, Date de fin: 31 mars 2018,
"The continuous migration of immune cells to lymph nodes (LN) is of utmost importance for the induction of both protective immunity as well as immunological tolerance. Despite this pivotal role, little is known regarding migration paths and the molecular cues regulating homing of immune cells that arrive via afferent lymphatic vessels to LN. This conspicuous lack of knowledge is primarily due to p...
Voir le projet
1
Participant partenaire
TERMINÉ
Immune and Neuromodulation Mediated by Alphaherpesviruses (INMA)
Date du début: 1 avr. 2014, Date de fin: 31 mars 2018,
Despite the advances against infectious diseases, morbidity and mortality still pose a very high social and economic impact. Viruses have developed a plethora of strategies to modulate the host. The main goal of my research is to investigate these strategies in order to understand viral immunomodulation, neuromodulation and pathogenesis. This will permit us to develop better intervention approache...
Voir le projet
1
Participant partenaire
TERMINÉ
Biomarkers of renal graft injuries in kidney allograft recipients (BIOMARGIN)
Date du début: 1 mars 2013, Date de fin: 28 févr. 2018,
In renal allograft recipients, 10-year graft survival has not improved over the past decades. Histological examination of graft biopsies has long been the gold standard to confirm graft injuries, but biopsies are invasive and histological grading is not very robust. There is thus a need for robust, non-invasive methods to predict and diagnose acute and chronic graft lesions, to improve patient tre...
Voir le projet
13
Participants partenaires
TERMINÉ
Parasite glycobiology and anti-parasitic strategies (GLYCOPAR)
Date du début: 1 déc. 2013, Date de fin: 30 nov. 2017,
"Protozoan parasites and helminths are the cause of some of the most devastating diseases worldwide and a major effort is needed to be able to control or eliminate these diseases. Glycoconjugates are abundant and ubiquitous on the surface of many parasites and they are frequently involved in their survival strategies by forming a protective barrier against host defences. A common feature of the pa...
Voir le projet
13
Participants partenaires
TERMINÉ
The effect of intracoronary reinfusion of bone marrow-derived mononuclear cells (BM-MNC) on all-cause mortality in acute myocardial infarction (BAMI)
Date du début: 1 nov. 2011, Date de fin: 31 oct. 2017,
Although the long term prognosis of patients suffering acute myocardial infarction (AMI) has improved since the introduction of reperfusion therapies and primary angioplasty, the 1 year mortality of patients with AMI and resultant left ventricular systolic dysfunction (LVSD) is still as high as 13%. A major reason for the high morbidity and mortality is that the heart has an inadequate regenerativ...
Voir le projet
23
Participants partenaires
TERMINÉ
Learning Analytics and Learning Process Management for Small Size Organizations in Higher Education
Date du début: 1 oct. 2015, Date de fin: 30 sept. 2017,
Learning Analytics (LA) as a key aspect of Learning Process Management (LPM) supports the measurement, analysis and reporting of data about learners and their contexts for purposes of understanding and optimizing learning and the environments in which it occurs (statement on Learning Analytics and Knowledge from the 1st International Conference from 2011).
LA focus on learning and teaching activ...
Voir le projet
5
Participants partenaires
TERMINÉ
novel bioreactor Platform for reprOducible, Scalable ExpansIonand cardiac DifferentiatiON of hiPSC in suspension culture (POSEIDON)
Date du début: 1 oct. 2015, Date de fin: 30 sept. 2017,
Human induced pluripotent stem cells (hiPSCs) have the potential to revolutionize biomedical sciences, however the standardised mass production, indispensable for their industrial and therapeutic use, is still a major challenge. Impeller stirred-tank bioreactors, currently used for hiPSC bioprocessing, impose detrimental stresses on cultured hiPSCs, resulting in heterogeneity of cells and cell-agg...
Voir le projet
1
Participant partenaire
TERMINÉ
Advances in Small Trials dEsign for Regulatory Innovation and eXcellence (ASTERIX)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,
"ASTERIX will contribute towards the expected impact listed in the work program by delivering validated innovative statistical design methodologies for cost efficient clinical trials deriving reliable results from trials in small population groups, especially focusing on rare diseases. It directly addresses the rights of the estimated 30 million European patients suffering from rare diseases to th...
Voir le projet