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 TERMINÉ 

Pathways to Alzheimer's disease (PATHAD)

Date du début: 1 déc. 2016, Date de fin: 30 nov. 2021,

Critical to our understanding of Alzheimer’s disease (AD) and also to finding therapies is determining how key pathological factors interact and relate to neuronal toxicity, symptoms and disease progression. My research has focussed on amyloid beta (Aβ) moities and demonstrated that cerebrospinal fluid (CSF) Aβ42 correlates with cerebral Aβ pathology; that Aβ accumulates in the brain 10-20 years p...
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 1

 TERMINÉ 

Maintaining the Human Mitochondrial Genome (DELMIT)

Date du début: 1 nov. 2016, Date de fin: 31 oct. 2021,

Mitochondria are required to convert food into usable energy forms and every cell contains thousands of them. Unlike most other cellular compartments, mitochondria have their own genomes (mtDNA) that encode for 13 of the about 90 proteins present in the respiratory chain. All proteins necessary for mtDNA replication, as well as transcription and translation of mtDNA-encoded genes, are encoded in t...
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 1

 TERMINÉ 

Biocompatible and Interactive Artificial Micro- and Nanoswimmers and Their Applications (ComplexSwimmers)

Date du début: 1 sept. 2016, Date de fin: 31 août 2021,

Microswimmers, i.e., biological and artificial microscopic objects capable of self-propulsion, have been attracting a growing interest from the biological and physical communities. From the fundamental side, their study can shed light on the far-from-equilibrium physics underlying the adaptive and collective behavior of biological entities such as chemotactic bacteria and eukaryotic cells. From th...
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 2

 TERMINÉ 

The evolution of barriers to gene exchange (BARRIERS)

Date du début: 1 sept. 2016, Date de fin: 31 août 2021,

Speciation is a central process in evolution that involves the origin of barriers to gene flow between populations. Species are typically isolated by several barriers and assembly of multiple barriers separating the same populations seems to be critical to the evolution of strong reproductive isolation. Barriers resulting from direct selection can become coincident through a process of coupling wh...
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 2

 TERMINÉ 

PRevention Of Malnutrition In Senior Subjects in the EU (PROMISS)

Date du début: 1 avr. 2016, Date de fin: 31 mars 2021,

PROMISS (PRevention Of Malnutrition In Senior Subjects in the EU) is a multi-country project aiming to turn the challenge of tackling malnutrition in community-dwelling older persons into an opportunity for healthy ageing for the future. The PROMISS consortium contains worldwide expertise in epidemiology, clinical trials, geriatrics, nutrition, physical activity, microbiomics, as well as in behavi...
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 24

 TERMINÉ 

BIOlogical therapy CYCLEs towards tailored, needs-driven, safer and cost-effective management of Crohn’s disease (BIOCYCLE)

Date du début: 1 avr. 2015, Date de fin: 31 mars 2021,

"The BIOCYCLE Project proposes to test and critically assess the benefits and risks of an innovative regimen for improving the treatment of Crohn’s disease (CD), a chronic immune-mediated inflammatory disease affecting the gastro-intestinal tract of an increasing number of patients. Currently, the combination of anti-TNFα monoclonal antibodies and immunosuppressants used without interruption is th...
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 13

 TERMINÉ 

Infrastructure and integrated tools for personalized learning of reading skill (iRead)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

The overarching aim of the iRead project is to develop a software infrastructure of personalised, adaptive technologies and a diverse set of applications for supporting learning and teaching of reading skills. The specific goals of the project proposed are to:1. Develop a scalable, cloud-based software infrastructure of open, interoperable components, including real-time user modelling and domai...
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 17

 TERMINÉ 

Critical Heritage Studies and the Future of Europe_Towards an integrated, interdisciplinary and transnational training model in cultural heritage research and management (CHEurope)

Date du début: 1 nov. 2016, Date de fin: 31 oct. 2020,

CHEurope focuses on developing a new integrated theoretical and methodological framework to enhance the academic and professional training and open future job opportunities in cultural heritage preservation, management and promotion. Heritage has commonly been perceived through its contingent relationship to other areas, preventing it to be considered as a ‘legitimate’ scientific discipline. Moreo...
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 8

 TERMINÉ 

Regulation of mitochondrial expression (REMIX)

Date du début: 1 oct. 2016, Date de fin: 30 sept. 2020,

Mitochondria are essential organelles found in every eukaryotic cell, required to convert food into usable energy. The mitochondrial oxidative phosphorylation (OXPHOS) system, which produces the majority of cellular energy in the form of ATP, is controlled by two distinct genomes: the nuclear and the mitochondrial genome (mtDNA). Mutations in mitochondrial genes encoded by either genome could caus...
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 9

 TERMINÉ 

Dexterous Transradial Osseointegrated Prosthesis with neural control and sensory feedback (DeTOP)

Date du début: 1 mars 2016, Date de fin: 29 févr. 2020,

This project addresses the scientific, technological and clinical problem of recovery of hand function after amputation. Despite decades of research and development on artificial limbs and neural interfaces, amputees continue to use technology for powered prostheses developed over 40 years ago, namely myoelectric prostheses controlled via superficial electrodes. These devices do not purposely prov...
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 7

 TERMINÉ 

Promoting Sustainable Freight Transport in Urban Contexts:Policy and Decision-Making Approaches (PROSFET)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2019,

Within a context of growing urban population, advances in urban logistics operations and improved local authority planning, especially in the field of the urban freight transport, can alleviate the associated negative environmental and economic impacts occurring in cities.Several types of stakeholders are involved in such urban logistics management processes. Among them, freight carriers and shipp...
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 9

 TERMINÉ 

Exploiting Protein Complexes that Induce Cell-death (EPIC)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

The formation of specific protein complexes are key events in life-and-death decisions made by cells. Inappropriate decisions underpin a plethora of disease conditions from degenerative diseases to cancer while the role of the complexes in these processes make them important therapeutic targets. Our ability to develop small molecules to target death-inducing protein complexes has been hampered by ...
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 5

 TERMINÉ 

Pathogen and Graphene (PANG)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

Complications related to infectious diseases have significantly reduced, particularly in the developed countries, due to the availability and use of broad-range antibiotics and wide variety of antimicrobial agents. Excessive use of antibiotics and antimicrobial agents increased significantly the number of multi-drug resistant (MDR) bacteria. This has resulted in a serious threat to public health. ...
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 8

 TERMINÉ 

Achieving Complex Collaborative Missions via Decentralized Control and Coordination of Interacting Robots (Co4Robots)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2019,

Imagine a scenario where multiple robots have been deployed to provide services such as object handling/transportation, or pickup and delivery operations. In such a context, different robots with varying capabilities must be coordinated in order to achieve various multi-tasking procedures. Thus, the effective supervision and coordination of the overall heterogeneous system mandates a decentralized...
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 7

 TERMINÉ 

Role of European Mobility and its Impacts in Narratives, Debates and EU Reforms (REMINDER)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2019,

The overarching goal of the project is to understand the economic, social, institutional and policy factors that have shaped the impacts of free movement and public debates about it. It aims to help European policymakers develop policy responses that inspire public trust, ensure the fairness and sustainability of free movement, and maintain inclusive policies that reduce inequalities across the co...
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 14

 TERMINÉ 

Metagenome and Bariatric Surgery - New Avenues to Treat Metabolic Disease (METABASE)

Date du début: 1 nov. 2014, Date de fin: 31 oct. 2019,

"Obesity and associated metabolic diseases such as type 2 diabetes are increasing worldwide and are the result of complex gene-environment interactions. Recent studies indicate that socio-demographic and environmental factors are more important for disease development than genetics, and we and others have demonstrated that the gut microbiota can be considered an environmental factor that contribut...
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 1

 TERMINÉ 

Endoplasmic Reticulum Stress in Health and Disease (TRAIN-ERS)

Date du début: 1 oct. 2015, Date de fin: 30 sept. 2019,

Endoplasmic reticulum (ER) stress is emerging as a common feature in the pathology of numerous diseases including cancer, neurodegenerative disorders, metabolic syndromes and inflammatory diseases. Thus ER stress represents a potential therapeutic intervention point to be exploited to develop novel therapies, diagnostic tools and markers for these diseases. However, exploitation is hampered by the...
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 12

 TERMINÉ 

EDUGATE - Multilingual teaching in early childhood education and care

Date du début: 1 sept. 2016, Date de fin: 31 août 2019,

EDUGATE project stands for Multilingual teaching in early childhood education and care and will last 36 months, starting in September 2016.The project is aimed at improving ECEC teachers and educators’ competences for supporting pre-school education providers in adopting innovative pedagogical methodologies and in providing high-quality Early Childhood Education and Care (ECEC). EDUGATE will impro...
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 7

 TERMINÉ 

European Network of STEM Professional Development Centres

Date du début: 1 sept. 2016, Date de fin: 31 août 2019,

To deal with the increasingly complex reality in class, which has accelerated in the last years, teachers need support through professional development (PD) activities to adopt new integrative methods. This need is particularly pronounced in STEM teaching (Science, Technology, Engineering and Mathematics) since STEM is a field in which all pupils, including migrants or those from disadvantaged bac...
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 14

 TERMINÉ 

Forging Ahead: Faking Sagas and Developing Concepts of Cultural Authenticity and National Identity in 17th- and 18th-Century Scandinavia (Forgery)

Date du début: 1 sept. 2017, Date de fin: 31 août 2019,

The high-stakes game of forgery, from priceless art to counterfeit banknotes, has stimulated public and professional interest for centuries. This project adds to the body of relevant examples, and feeds back into the broader theoretical frameworks, by looking at a number of texts which appeared for the first time in 17th- and 18th-century Scandinavia and were revealed to be forgeries. The most fam...
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 1

 TERMINÉ 

Perception and Evaluation of Regional and Cohesion policies by Europeans and Identification with the Values of Europe (PERCEIVE)

Date du début: 1 sept. 2016, Date de fin: 31 août 2019,

The PERCEIVE (Perception and Evaluation of Regional and Cohesion policies by Europeans and Identification with the Values of Europe) project aims at both mapping and explaining inter- and intra-regional variations in: a) the experiences and results of cohesion policy implementation, b) citizens’ awareness and appreciation of EU efforts for delivering cohesion and c) European identities and citizen...
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 8

 TERMINÉ 

Nanomaterial FAte and Speciation in the Environment (NanoFASE)

Date du début: 1 sept. 2015, Date de fin: 31 août 2019,

Concept: NanoFASE will deliver an integrated Exposure Assessment Framework, including methods, parameter values, model and guidance that will allow Industry to assess the full diversity of industrial nano-enabled products to a standard acceptable in regulatory registrations. Methods to assess how use phases, waste streams and environmental compartments (air, soil, water biota) act as “reactors” in...
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 39

 TERMINÉ 

Efficacy and safety of low-dose IL-2 (ld-IL-2) as a Treg enhancer for anti-neuroinflammatory therapy in newly diagnosed Amyotrophic Lateral Sclerosis (ALS) patients (MIROCALS)

Date du début: 1 sept. 2015, Date de fin: 31 août 2019,

Amyotrophic Lateral Sclerosis (ALS) is a fatal degenerative disorder of the brain and spinal cord affecting some 40,000 individuals in Europe, causing 11,000 deaths each year. Our pioneering work on riluzole showed that it is possible to modify ALS progression but all subsequent trials of potential neuroprotective agents have failed. Thus, drug development in ALS, including trial design, patient s...
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 12

 TERMINÉ 

ALK Activation as a target of TRAanslational Science (ALKATRAS): Break free from cancer (ALKATRAS)

Date du début: 1 sept. 2015, Date de fin: 31 août 2019,

This ETN is embedded into an established international research programme; The European Research Initiative on Anaplastic Lymphoma Kinase (ALK)-related malignancies (ERIA; www.erialcl.net) is an existing and functional network of 13 partners, which will cosset and nurture a cohort of early stage researchers to become confident, competent, independent and well-connected European scientists with exc...
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 13

 TERMINÉ 

Learning communities for peace

Date du début: 1 oct. 2016, Date de fin: 31 mai 2019,

[Context/background of project]The EU faces a complex of crises – a huge influx of refugees, and threats from terrorism and radicalisation. At the same time, many urban areas suffer from structural inequalities and often dysfunctional integration policies. The resulting tensions have intensified the fear of difference. The erosion of trust particularly affects strongly migrant communities and the ...
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 6

 TERMINÉ 

Development and Demonstration of monitoring strategies and technologies for geological disposal (Modern2020)

Date du début: 1 juin 2015, Date de fin: 31 mai 2019,

The Modern2020 project aims at providing the means for developing and implementing an effective and efficient repository operational monitoring programme, taking into account the requirements of specific national programmes. The work allows advanced national radioactive waste disposal programmes to design monitoring systems suitable for deployment when repositories start operating in the next deca...
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 28

 TERMINÉ 

The Peformance of Democracies (PERDEM)

Date du début: 1 mai 2014, Date de fin: 30 avr. 2019,

"This project will use an institutional approach to answer the question why some democracies perform better than others. Democratic systems can be institutionalized in innumerous ways given variation in for example party system, electoral system, type of public administration, judicial control and type of legal system, degree of lobbyism, degree of decentralization, rules for the public budget, po...
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 1

 TERMINÉ 

Environmental Research Infrastructures Providing Shared Solutions for Science and Society (ENVRI PLUS)

Date du début: 1 mai 2015, Date de fin: 30 avr. 2019,

ENVRIPLUS is a cluster of research infrastructures (RIs) for Environmental and Earth System sciences, built around ESFRI roadmap and associating leading e-infrastructures and Integrating Activities together with technical specialist partners. ENVRIPLUS is driven by 3 overarching goals: 1) favoring cross-fertilization between infrastructures, 2) implementing innovative concepts and devices across R...
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 37

 TERMINÉ 

Integrating Epidemiology and Experimental Biology to Improve Risk Assessment of Exposure to Mixtures of Endocrine Disruptive Compounds (EDC-MixRisk)

Date du début: 1 mai 2015, Date de fin: 30 avr. 2019,

A large body of evidence supports associations between exposure to anthropogenic chemicals and endocrine disruptive effects, leading to disorders in humans and wildlife. Based on the scientific documentation it is beyond doubt that endocrine disrupting chemicals (EDCs) are of concern and need to be handled according to the risks they pose, as single chemicals or as mixtures. To develop chemical ri...
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 14

 TERMINÉ 

Macroevolutionary Rates by Integrating Phylogenomics and Ancestral character States - A study on Neotropical butterfly evolution. (MARIPOSAS)

Date du début: 16 janv. 2017, Date de fin: 15 janv. 2019,

Delving into the factors and processes driving biodiversity is essential to understand the potential consequences of environmental changes in species-rich and vulnerable ecosystems. MARIPOSAS (Macroevolutionary Rates by Integrating Phylogenomics and Ancestral character States – Mariposas is also the Spanish translation for butterflies) aims to unveil the macroevolutionary mechanisms governing dive...
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 1

 TERMINÉ 

The Neurobiology of Decision-Making in Eating - Innovative Tools (NUDGE-IT)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2018,

Nudge-it engages internationally leading experts in the neurobiology of motivational behaviour, the neuroscience of reward pathways, the neuroendocrinology of homeostatic regulation of appetite, experimental psychology, functional brain imaging, behavioural economics, and computational modelling. They will work together to develop new tools and approaches that can provide the evidence needed to in...
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 10

 TERMINÉ 

Advanced XFEL and Synchrotron based Probes of Protein Structure and Dynamics (X-probe)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2018,

This cross-disciplinary Marie Curie Innovative Training Network builds upon the transformative opportunities created by existing X-ray sources and new sources soon to be operative in Europe. These opportunities include using ultrafast X-ray sources to extract time-dependent structural information from proteins; and revolutionary possibilities created by X-ray Free Electron Laser radiation for an e...
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 9

 TERMINÉ 

Vaccination In Atherosclerosis (VIA)

Date du début: 1 déc. 2013, Date de fin: 30 nov. 2018,

"Cardiovascular disease (CVD) is still a leading cause of death in the European Union (EU) accounting for nearly half of all deaths in Europe (48%). In addition, CVD complications lead to a vast number of hospitalizations and thus to a great burden of health care costs in the EU. Atherosclerosis and its final complication, plaque rupture and subsequent infarct in heart or brain, is the main underl...
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 12

 TERMINÉ 

Metagenomics in Cardiometabolic Diseases (METACARDIS)

Date du début: 1 nov. 2012, Date de fin: 31 oct. 2018,

METACARDIS applies a systems medicine multilevel approach to identify biological relationships between gut microbiota, assessed by metagenomics, and host genome expression regulation, which will improve understanding and innovative care of cardiometabolic diseases (CMD) and their comorbidities. CMD comprise metabolic (obesity, diabetes) and heart diseases characterized by a chronic evolution in ag...
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 18

 TERMINÉ 

Solutions for present and future emerging pollutants in land and water resources management (SOLUTIONS)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2018,

"SOLUTIONS will deliver a conceptual framework for the evidence-based development of environmental and water policies. This will integrate innovative chemical and effect-based monitoring tools with a full set of exposure, effect and risk models and assessment options. Uniquely, SOLUTIONS taps (i) expertise of leading European scientists of major FP6/FP7 projects on chemicals in the water cycle, (i...
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 41

 TERMINÉ 

EdUCATe - EUropean nonviolent Conflict management for educators : Advocacy and Training

Date du début: 1 sept. 2015, Date de fin: 31 août 2018,

For the proposed project, six European partner organisations formed a transnational team and intend to elaborate the intensity of their collaboration by combining each and every one’s excellence in constructive and non-violent conflict management as well as their competency in dialoguing with educational policy agencies and political bodies. The international team consists of two NGO’s (Croatia,...
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 6

 TERMINÉ 

Modernising European Higher Music Education through Improvisation

Date du début: 1 sept. 2015, Date de fin: 31 août 2018,

The ‘Modernising European Higher Music Education through Improvisation - METRIC’ project wants to contribute to improving the employability of future music graduates through the artistic, pedagogical and entrepreneurial development of higher music education studies in the area of improvisation as a response to the rapidly changing employment situation in the music profession. In performance curric...
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 14

 TERMINÉ 

NEURONLINE : Creating on-line educational resources for a Life Long Learning Master of neuroscience

Date du début: 1 sept. 2015, Date de fin: 31 août 2018,

The present project is aiming to implement an on-line master programme of Neuroscience (Neuron Line) providing Lifelong Learning for professionals and initial training for distant students. Part of the education programme will be available for specific update that can be certified by University Diploma. The project gathers a University consortium that partly exists already, and the recently create...
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 9

 TERMINÉ 

Lexicography and Open Access Web Based Dictionaries for Languages with Few Speakers

Date du début: 1 sept. 2015, Date de fin: 31 août 2018,

Open access web-based dictionaries are paramount tools in the battle to preserve linguistic diversity in the digital age. In an effort to sustain the local language, the University of Iceland (UoI) developed a high quality web-based lexical database, counting some 50.000 words and expressions with numerous illustrations and examples. Open access dictionaries online towards Danish, Swedish and Norw...
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 3

 TERMINÉ 

Let's Fathers, Come Preschools!

Date du début: 1 sept. 2016, Date de fin: 31 août 2018,

let's Fathers Come to Preschool (LFCTP) is a Erasmus+ KA2 strategic partnership project on the field of higher education between Baskent University from TR, and Gothenburg University from Sweden, Stricting Drio from NL and Life-Long Learning Association from TR. Today, father involvement (FI) is now accepted as an important factor that lead healthy child developement. Mainly father involvement res...
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 4