16 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Highly Multiplexed Affinity Proteomics for Point of Care Diagnostics (MultiPOC)
Date du début: 1 avr. 2014, Date de fin: 31 mars 2019,
The main objective is the development of highly multiplexed affinity proteomics tools for point of care diagnostics. Enabled by the world's largest resource of antibodies to human protein targets generated within the framework of the Human Protein Atlas program, the aim of this application is to develop new concepts in translational medical research to allow dramatic improvement in performance and ...
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2
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TERMINÉ
DIabetes REsearCh on patient sTratification (DIRECT)
Date du début: 1 févr. 2012, Date de fin: 31 janv. 2019,
The overarching aims of the DIRECT consortium, consisting of 20 leading academic groups in diabetes and 5 EFPIA companies, are to identify biomarkers that address current bottlenecks in diabetes drug development and to develop a stratified medicines approach to treatment of type 2 diabetes with either existing or novel therapies.There is heterogeneity in who develops diabetes, the rate at which th ...
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27
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TERMINÉ
PRIMES: Protein interaction machines in oncogenic EGF receptor signalling (PRIMES)
Date du début: 1 déc. 2011, Date de fin: 30 nov. 2016,
"PRIMES focuses on the role of protein interactions to assemble dynamic molecular machines that receive and process information to coordinate cellular responses. PRIMES investigates the following: (i) How do protein interactions contribute to the generation of biological specificity in signalling? (ii) How do pathogenetic perturbations affect protein interaction networks? (iii) How can we exploit ...
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14
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TERMINÉ
The development and evaluation of Multipurpose crops as new biorefining feedstocks for the production of industrial BioProducts and biomass (MultiBioPro)
Date du début: 1 oct. 2012, Date de fin: 30 sept. 2016,
The overall strategic objective of MultiBioPro is to exploit natural resources from genetic varieties of two industry-utilized plant species, poplar and the tobacco tree Nicotiana glauca, for direct applicability to novel industrial end products. The consortium will explore already existing poplar and N. glauca genotypes in parallel with innovative state-of-the-art translational research from the ...
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12
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TERMINÉ
"High Efficient, Single-Use-Bioreactor simulating mammalian tissue conditions for expression and proliferation" (HESUB)
Date du début: 1 mai 2013, Date de fin: 30 avr. 2016,
A unique combination of earlier EU funded projects allow four research SME´s to create a combined most visionary and innovative product for improved health. There is a strategic decision from pharmaceutical companies and hospitals for:1. continues expressing of biologicals to fulfill the expectation to “personalized medicine” and 2. proliferation of cells to support therapeutic applications and 3. ...
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5
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TERMINÉ
Magnetic Isolation and moleculaR Analysis of single CircuLating and disseminated tumor cElls on chip (MIRACLE)
Date du début: 1 sept. 2010, Date de fin: 31 mai 2015,
Cancer remains a prominent health concern afflicting modern societies. Continuous innovations and introduction of new technologies are essential to level or even reduce current healthcare spending. As the analysis of occult tumour cells (OTC) in blood or bone marrow is most promising in this respect, MIRACLE aims to develop a low-cost, fully automated, integrated lab-on-a-chip (LOC) system for the ...
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15
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TERMINÉ
European large-scale functional genomics in the rat for translational research (EURATRANS)
Date du début: 1 avr. 2010, Date de fin: 31 mars 2015,
Genetic studies in model organisms and humans, including human genome-wide association studies, have pinpointed genomic regions that contribute susceptibility to common disease. However, to date, these data have provided limited insights into the genes, molecular pathways and mechanisms underlying disease pathophysiology.The EU FP6 Euratools consortium has been a remarkable success that establishe ...
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19
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TERMINÉ
Protein Binders for Characterisation of Human Proteome Function: Generation, Validation, Application (AFFINOMICS)
Date du début: 1 avr. 2010, Date de fin: 31 mars 2015,
The Affinomics programme aims to leverage existing efforts in Europe to generate large-scale resources of validated protein-binding molecules (‘binders’) as affinity reagents for characterisation of the human proteome and to apply them in comprehensive structural and functional analyses of protein expression, interactions and complexes. Proteome targets will be focused on five categories of inter- ...
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20
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TERMINÉ
Cancer Genomics of the Kidney (CAGEKID)
Date du début: 1 mars 2010, Date de fin: 31 août 2014,
The International Cancer Genome Consortium (ICGC) has the goal of obtaining a comprehensive description of genomic, transcriptomic and epigenomic changes in 50 different tumour types and/or subtypes, with the aim of elucidating the genomic changes present in the many forms of cancers that contribute to the burden of disease throughout the world. We present a proposal for a European contribution to ...
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15
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TERMINÉ
Massive Digital sequencing by binary DNA (Digital Sequencing)
Date du début: 1 déc. 2009, Date de fin: 31 mai 2014,
DNA sequencing costs have fallen more than 50-fold over the past decade, driven part by tools, technology and process improvements made during the Human Genome Project. However, it still costs around $10 million to sequence 3 billion base pairs - the amount of DNA found in the genomes of humans and other mammals. 1st generation sequencing platforms, which are based upon capillary electrophoresis ...
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5
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TERMINÉ
The development of very high performance bioderived composite materials of cellulose nanofibres and polysaccharides (NanoCelluComp)
Date du début: 1 mars 2011, Date de fin: 31 mars 2014,
The overall aim of the NanoCelluComp project is to develop a technology to utilise the high mechanical performance of cellulose nanofibres, obtained from food processing waste streams, combined with bioderived matrix materials, for the manufacture of high performance composite materials that will replace glass and carbon fibre reinforced plastics in many applications including transportation, wind ...
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12
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TERMINÉ
PROteomics SPECification in Time and Space (PROSPECTS)
Date du début: 1 avr. 2008, Date de fin: 31 mars 2013,
"Proteomics is a major new field in biomedical research, which deals with the large-scale identification and characterization of large groups of proteins, or “proteomes”. These can either be the components of a subcellular organelle or compartment, or even the entire protein complement of whole cells and tissues. Proteomics is essential in the functional annotation of the genome and in future atte ...
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11
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TERMINÉ
European Network for Genetic and Genomic Epidemiology (ENGAGE)
Date du début: 1 janv. 2008, Date de fin: 31 déc. 2012,
"ENGAGE (European Network for Genetic and Genomic Epidemiology) has, as its central objective, the translation of the wealth of data emerging from large-scale research efforts in molecular epidemiology into information of direct relevance to future advances in clinical medicine. ENGAGE will do this through the integration of very large-scale genetic and phenotypic data already available from a sub ...
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26
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TERMINÉ
Identifying and validating pre-clinical biomarkers for diagnostics and therapeutics of Neuromuscular Disorders (BIO-NMD)
Date du début: 1 déc. 2009, Date de fin: 30 nov. 2012,
"The rapidly expanding knowledge of NMDs genetic diagnosis, pathogenesis and therapeutic possibilities has provided new targets for disease characterisation, early diagnosis, drug discovery and development as well as has raised many questions about how to translate this knowledge into clinical practice as (initial) clinical trials typically run for such a short time that clinical improvement can h ...
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15
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TERMINÉ
Improving Plant Cell Walls for Use as a Renewable Industrial Feedstock (RENEWALL)
Date du début: 1 août 2008, Date de fin: 31 juil. 2012,
"With oil reserves diminishing and the effects of industrial emissions on global climate, there is a need for renewable carbon-neutral industrial feedstocks. First generation biorefineries, producing biofuels and bioplastics by the fermentation of sugar or starch, are seeing a rapid expansion and are adding stress to food supplies. A more sustainable option is to use plant biomass from agricultura ...
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17
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TERMINÉ
IT Future of Medicine (ITFoM)
Date du début: 1 mai 2011, Date de fin: 30 avr. 2012,
Data-rich, individualised medicine poses unprecedented challenges for IT, in hardware, storage and communication. We propose a data-driven, individualised medicine of the future, based on molecular/physiological/anatomical data from individual patients. We shall make general models of human pathways, tissues, diseases and ultimately of the human as a whole. Individualised versions of the models, ...
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