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The in vivo roles of tRNA modification (TRNAMODI)

Date du début: 1 déc. 2012, Date de fin: 30 nov. 2017,

tRNA molecules are key in translating the genetic information into a protein sequence and critical for all aspects of cellular metabolism. Interestingly, tRNAs carry a plethora of chemical modifications, thought to regulate their function. Many of these modifications are evolutionarily highly conserved, and some linked to human degenerative diseases and cancer. However, we know little about their ...
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