Plus de 40 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Embodied Emotion Regulation (EMBER)
Date du début: 1 avr. 2012, Date de fin: 31 mars 2018,
In everyday life, people frequently engage in bodily activities to regulate their emotions, such as physical exercise to reduce stress, eating tasty foods to improve one's mood, or practice meditation to achieve deep states of relaxation. In spite of such widespread practices, the wisdom of using the body in emotion regulation is highly contested within psychological science. Some studies have sho ...
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2
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TERMINÉ
Next Zero Energy Buildings at lowest Cost by using Competitive Sustainable Technology (NEXT-BUILDINGS)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2017,
This project is about the demonstration of very low energy buildings. In all demonstrations, the ambition is net zero carbon/energy or better (active or plus-energy house). The project paves the way for large scale implementation of energy neutral buildings/neighbourhoods as foreseen in the Energy Performance of Buildings directive and the pilots are running more than five years ahead of the goal ...
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14
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TERMINÉ
Thylakoid membrane in action: acclimation strategies in algae and plants (ASAP)
Date du début: 1 déc. 2011, Date de fin: 30 nov. 2017,
Life on earth is sustained by the process that converts sunlight energy into chemical energy: photosynthesis. This process is operating near the boundary between life and death: if the absorbed energy exceeds the capacity of the metabolic reactions, it can result in photo-oxidation events that can cause the death of the organism. Over-excitation is happening quite often: oxygenic organisms are exp ...
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2
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TERMINÉ
Long-term effects of early nutrition on later health (EARLYNUTRITION)
Date du début: 1 févr. 2012, Date de fin: 31 oct. 2017,
Nutrition during early development has an important impact on later health, particularly through greater obesity risk, as demonstrated by FP6 EARNEST. EarlyNutrition explores the current key hypotheses on likely causes and pathways to prevention of early life origins of obesity (specifically adiposity) and associated disorders. We bring extraordinary expertise and study populations of 470,000 indi ...
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40
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TERMINÉ
Model-based preclinical development of anti-tuberculosis drug combinations (PREDICT-TB)
Date du début: 1 mai 2012, Date de fin: 30 oct. 2017,
Drug development in TB requires new integrated methods to transition the novel combination regimens needed to shorten first-line therapy and combat multi-drug resistance. Although new agents are emerging, the path to registration of such regimens remains uncertain while capacity for pivotal trials is limited. Selection and optimization of drug combinations for development depends on preclinical sy ...
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23
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TERMINÉ
Beyond the Genetics of Addiction (ADDICTION)
Date du début: 1 déc. 2011, Date de fin: 31 mai 2017,
My proposal seeks to explain the complex interplay between genetic and environmental causes of individual variation in substance use and the risk for abuse. Substance use is common. Substances like nicotine and cannabis have well-known negative health consequences, while alcohol and caffeine use may be both beneficial and detrimental, depending on quantity and frequency of use. Twin studies (inclu ...
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3
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TERMINÉ
4D-EEG: A new tool to investigate the spatial and temporal activity patterns in the brain (4D-EEG)
Date du début: 1 juin 2012, Date de fin: 31 mai 2017,
"Our first goal is to develop a new tool to determine brain activity with a high temporal (< 1 msec) and spatial (about 2 mm) resolution with the focus on motor control. High density EEG (up to 256 electrodes) will be used for EEG source localization. Advanced force-controlled robot manipulators will be used to impose continuous force perturbations to the joints. Advanced closed-loop system identi ...
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3
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TERMINÉ
Imaging of Neuroinflammation in Neurodegenerative Diseases (INMiND)
Date du début: 1 mars 2012, Date de fin: 28 févr. 2017,
The goal of this proposal (INMiND) is to carry out collaborative research on molecular mechanisms that link neuroinflammation with neurodegeneration in order to identify novel biological targets for activated microglia, which may serve for both diagnostic and therapeutic purposes, and to translate this knowledge into the clinic. The general objectives of INMiND are:(i) to identify novel mechanisms ...
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32
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TERMINÉ
The Dynamic Protein Matrix in Photosynthesis: From Disorder to Life (PHOTPROT)
Date du début: 1 févr. 2011, Date de fin: 31 janv. 2017,
In photosynthesis solar light is harvested by an antenna, the energy is transferred to the photosynthetic reaction center where a charge separation occurs. These processes occur on an ultrafast timescale and result in a stable product. The photosynthetic apparatus consists of a complex set of pigment-proteins that perform these delicate processes with a quantum efficiency close to 1. Proteins are ...
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3
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TERMINÉ
Optical dissection of circuits underlying fast cholinergic signalling during cognitive behaviour (BRAINSIGNALS)
Date du début: 1 nov. 2011, Date de fin: 31 oct. 2016,
Our ability to think, to memorize and focus our thoughts depends on acetylcholine signaling in the brain. The loss of cholinergic signalling in for instance Alzheimer’s disease strongly compromises these cognitive abilities. The traditional view on the role of cholinergic input to the neocortex is that slowly changing levels of extracellular acetylcholine (ACh) mediate different arousal states. Th ...
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2
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TERMINÉ
Quantifying CO2 emissions from tropical deforestation to ‘close’ the global carbon budget (DE-CO2)
Date du début: 1 nov. 2011, Date de fin: 31 oct. 2016,
The land and oceans have mitigated climate change by taking up about half of the anthropogenic CO2 emitted since the industrial revolution. However, these ‘sinks’ are predicted to lose their efficiency. Globally, the combined sink strength of the land and ocean can be calculated indirectly as the difference between anthropogenic emissions – from fossil fuel burning and deforestation – and the atmo ...
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2
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TERMINÉ
A novel generation of skin substitutes to clinically treat a broad spectrum of severe skin defects (EUROSKINGRAFT)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2016,
Large full-thickness skin defects resulting from burns, soft tissue trauma, congenital giant nevi, tumour resection, and disease leading to skin necrosis, represent a significant and common clinical problem worldwide. This problem is far from being solved. The main challenge encountered is that most autologous skin grafting techniques are based on transplanting split-thickness skin (the today’s go ...
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11
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TERMINÉ
Transitioning towards Urban Resilience and Sustainability (TURAS)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2016,
The “TURaS” project aims to bring together urban communities, researchers, local authorities and SMEs to research, develop, demonstrate and disseminate transition strategies and scenarios to enable European cities and their rural interfaces to build vitally-needed resilience in the face of significant sustainability challenges. To ensure maximum impact, the TURaS project has developed an innovati ...
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34
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TERMINÉ
The MEtabolic Road to DIAstolic Heart Failure (MEDIA)
Date du début: 1 janv. 2011, Date de fin: 30 juin 2016,
More than 50% of heart failure (HF) patients present without a major deficit of left ventricular (LV) systolic function and are presumed to suffer from diastolic HF (DHF) because diastolic LV distensibility is usually impaired in these patients. The vast majority (~80%) of DHF patients is exposed to metabolic risk factors. The MEDIA consortium therefore investigates:1) how metabolic derangements c ...
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23
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TERMINÉ
Rosetta s Way Back to the Source: Towards Reverse Engineering of Complex Software (ROSETTA)
Date du début: 1 mai 2011, Date de fin: 30 avr. 2016,
We propose a research program (Rossetta) towards reverse engineering of complex software that is available only in binary form. Most of the commercial software industry assumes that compilation (the translation of source code to binary code), is irreversible in practice for real applications. The research question for Rosetta is whether this irreversibility assumption is reasonable. If successful, ...
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2
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TERMINÉ
COMBATING CLIMATE CHANGE: Political economy of Green Paradoxes (GP)
Date du début: 1 mai 2011, Date de fin: 30 avr. 2016,
"Green Paradoxes are defined as the phenomenon that climate change policies can have counterproductive effects. For example, a subsidy on clean energy from renewable resources (solar, wind) will decrease the price at which this energy is supplied. But if the price still exceeds the cost of fossil fuel extraction and given that available stocks will be depleted, the price decrease will speed up the ...
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3
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TERMINÉ
Sarcomere based Signals in Muscle Remodelling (SARCOSI)
Date du début: 1 avr. 2012, Date de fin: 31 mars 2016,
The sarcomere is the structural unit of striated muscle tissues where thick and thin filaments cooperate to achieve muscle contraction. Recently it is becoming increasingly clear that sarcomeres have in addition to muscle contraction also important signaling functions: Stretch and strain sensing signalosomes are assembled by the giant muscle proteins titin and nebulin, that in turn are embedded in ...
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14
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TERMINÉ
Sustainable prevention of obesity through integrated strategies (SPOTLIGHT)
Date du début: 1 mars 2012, Date de fin: 29 févr. 2016,
BACKGROUNDThe prevalence of overweight and obesity in Europe is high and contribute to mortality and the burden of many chronic diseases, especially within groups of lower social-economic status. Obesity is largely determined by modifiable lifestyle dependent risk factors such as reduced physical activity, sedentary behaviour and an unhealthy diet. There is growing evidence that influences on indi ...
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16
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TERMINÉ
Earth system Model Bias Reduction and assessing Abrupt Climate change (EMBRACE)
Date du début: 1 nov. 2011, Date de fin: 29 févr. 2016,
EMBRACE brings together the leading Earth System Models (ESMs) in Europe around a common set of objectives to improve our ability to (i) simulate the Earth System and (ii) make reliable projections of future global change. EMBRACE builds on the existing European collaboration network in Earth System Modelling and will be the main European input to international efforts in this field over the comin ...
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20
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TERMINÉ
Predictive Genomic Biomarkers Methods for Combination Bevacizumab (Avastin) Therapy in Metastatic Colorectal Cancer (ANGIOPREDICT)
Date du début: 1 févr. 2012, Date de fin: 31 janv. 2016,
In recent years the treatment paradigm for metastatic colorectal cancer (mCRC) has evolved in complexity to include newly developed targeted therapeutics. In 2004 bevacizumab (bvz) [Avastin] became the first anti-angiogenic drug to be licensed in malignant disease, based on the results of a randomised trial in advanced metastatic colorectal cancer. Nevertheless, over the past six year period emerg ...
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12
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TERMINÉ
Effective Communication in Outbreak Management: development of an evidence-based tool for Europe (E-COM@EU)
Date du début: 1 févr. 2012, Date de fin: 31 janv. 2016,
Although scientific knowledge to respond to outbreaks has increased, deficiencies remain in the ability of health authorities to communicate the need for large-scale measures such as vaccination and antiviral therapy and increase its acceptance. For effective behavioural and communication strategies, integration is needed of social, behavioural, communication and media sciences.We bring together t ...
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13
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TERMINÉ
Integrated non-CO2 Greenhouse gas Observing System (INGOS)
Date du début: 1 oct. 2011, Date de fin: 31 déc. 2015,
InGOS will support and integrate the observing capacity of Europe for non-CO2 greenhouse gases (NCGHG: CH4, N2O, SF6, H2 and halocarbons). The emissions of these gases are very uncertain and it is unknown how future climate change will feedback into the land use coupled emissions of CH4 and N2O. The NCGHG atmospheric abundances will increase further in the future and the emissions of these gases a ...
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39
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TERMINÉ
Dissecting a minimal genome: a physical investigation of DNA transactions in mitochondria (PHYSGENE)
Date du début: 1 janv. 2011, Date de fin: 31 déc. 2015,
I propose to unravel parts of the mechanochemistry of two key genome transactions: replication and transcription using an array of single-molecule techniques. To this end, I propose to study the minimal genomic machinery of mitochondria. Mitochondria are organelles in eukaryotic cells that contain their own DNA (mtDNA). Significant understanding of the biochemistry of DNA transactions in mitochond ...
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2
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TERMINÉ
Positive health effects of the natural outdoor environment in typical populations in different regions in Europe (PHENOTYPE) (PHENOTYPE)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,
Indications exist that close contact with nature brings benefits to human health and well-being. The proposed work will investigate the interconnections between exposure to natural outdoor environments, in both rural and urban settings, and better human health and well-being in the North West, South and East of Europe. The project will explore the underlying mechanisms at work (stress reduction/re ...
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13
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TERMINÉ
Building data bridges between biological and medical infrastructures in Europe (BIOMEDBRIDGES)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,
The ESFRI infrastructures in Biological and BioMedical Sciences face substantial challenges in accessing and sharing data and resources. The BioMedBridges consortium brings together the six established ESFRI infrastructures with common goals to define, implement and deliver data interoperability across the biological and biomedical domains.The first objective is to ensure that interoperable stand ...
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26
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TERMINÉ
Systems Networks Norms (SYSNORM)
Date du début: 1 janv. 2013, Date de fin: 31 déc. 2015,
Genomic sciences are driving progress in biology at an unprecedented pace, most recently through third-generation sequencing and synthetic biology. These achievements challenge commonly accepted biological concepts and assumptions in the humanities. In this Fellowship I will investigate the impact of genomic sciences on theory development in the social and human sciences, with focus on philosophy ...
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4
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TERMINÉ
Vitamin D And LIfestyle Intervention for Gestational Diabetes Mellitus (GDM) Prevention (DALI)
Date du début: 1 mars 2010, Date de fin: 31 déc. 2015,
Europe is facing a rapidly growing threat from Type 2 diabetes mellitus (T2D), which is undoubtedly associated with an unhealthy diet and a more sedentary lifestyle. Evidence is accumulating that gestational diabetes mellitus (GDM) may be playing a role in this process. Thus it provides a significant opportunity for preventing future T2D. Not only is GDM prevalence on the rise, but intrauterine ex ...
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18
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TERMINÉ
Developmental neurotoxicity assessment of mixtures in children (DENAMIC)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,
Various recent epidemiological studies have indicated that exposure to low doses of environmental biologically active contaminants during human development can alter gene expression and have deleterious effects on cognitive development in childhood. The DENAMIC project is ultimately focused on reducing such effects of environmental contamination on learning and developmental disorders in children. ...
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18
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TERMINÉ
The Integrated Initiative of European Laser Research Infrastructures III (LASERLAB-EUROPE)
Date du début: 1 juin 2012, Date de fin: 30 nov. 2015,
LASERLAB-EUROPE III is the European Consortium of major Laser Research Infrastructures, forming a FP7 Integrated Infrastructure Initiative. Geographically it covers the majority of European member states, following recent efforts to include partners from all over Europe 27. Scientifically, it covers many areas of laser science and applications with particular emphasis on short-pulses and high-inte ...
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26
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TERMINÉ
European Training and Research in Peritoneal Dialysis (EUTRIPD)
Date du début: 1 déc. 2011, Date de fin: 30 nov. 2015,
Peritoneal dialysis (PD) and haemodialysis (HD) are life-saving renal replacement therapies for more than 200,000 patients with chronic kidney disease in Europe, and this number increases annually. Although PD and HD have similar mortality rates, PD offers major advantages in terms of quality of life, costs, home-based treatment opportunities and early patient survival. Moreover, PD, rather than H ...
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13
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TERMINÉ
REstoring rivers FOR effective catchment Management (REFORM)
Date du début: 1 nov. 2011, Date de fin: 31 oct. 2015,
REFORM is targeted towards development of guidance and tools to make river restoration and mitigation measures more cost-effective and to support the 2nd and future River Basin Management Plans (RMBPs) for the WFD. Aims of REFORM are (1) to provide a framework for improving the success of hydromorphological restoration measures and (2) to assess more effectively the state of rivers, floodplains an ...
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28
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TERMINÉ
Changing Permafrost in the Arctic and its Global Effects in the 21st Century (PAGE21)
Date du début: 1 nov. 2011, Date de fin: 31 oct. 2015,
Permafrost is defined as ground that remains continuously at or below 0°C for at least two consecutive years; some 24% of the land surface in the northern Hemisphere is classified as permafrost. In the Northern high latitudes, strong warming has been observed over the recent decades, and climate models project strong future warming. A projected decline in the extent of permafrost will have a major ...
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20
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TERMINÉ
Choosing Efficient Combinations of Policy Instruments for Low-carbon development and Innovation to Achieve Europe's 2050 climate targets (CECILIA2050)
Date du début: 1 sept. 2012, Date de fin: 31 oct. 2015,
Europe needs to transform itself to a low-carbon economy by mid-century. The existing instrument mix needs to be scaled up drastically to initiate the changes needed across the economy. As the scale and scope of instruments increases, their interaction becomes more important, as do constraints on the political, legal and administrative feasibility. To evaluate their efficiency and effectiveness, i ...
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12
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TERMINÉ
Transglutaminase in disease: a novel therapeutic target? (TRANSPATH)
Date du début: 1 nov. 2011, Date de fin: 31 oct. 2015,
"TRANSPATH is a multisectorial Network designed to facilitate the exchange of knowledge and technology between 7 leading European research teams and 3 SME partners and 2 associate SME Partners involved in basic and applied research into transglutaminase (TG) related human diseases. Its ambitions are to accelerate the development of new strategies for the treatment and diagnosis of human diseases ...
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12
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TERMINÉ
Innovative biodiagnosis meets chemical structure elucidation – Novel tools in effect directed analysis to support the identification and monitoring of emerging toxicants on a European scale (EDA-EMERGE)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2015,
"EDA-EMERGE aims to train a new generation of young scientists in the interdisciplinary techniques required to meet the major challenges in the monitoring, assessment and management of toxic pollution in European river basins considering the enormous complexity of contamination, effects and cause-effect relationships. By integrating innovative mode-of-action based biodiagnostic tools including in ...
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12
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TERMINÉ
Safety Evaluation of Adverse Reactions in Diabetes (SAFEGUARD)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2015,
"In 2010 a widely marketed drug for the treatment of type 2 diabetes (T2DM) (rosiglitazone) was taken from the market as it was associated with an increased risk of myocardial infarction, a T2DM complication it was actually supposed to prevent. This example shows several things. First, the approval requirements do not guarantee a longer term positive benefit risk profile. Second, large scale postm ...
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19
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TERMINÉ
Isotope forensics meets biogeochemistry – linking sources and sinks of organic contaminants by compound specific isotope investigation (CSI:ENVIRONMENT)
Date du début: 1 nov. 2010, Date de fin: 31 août 2015,
"The initial training network CSI: ENVIRONMENT aims at training 16 young scientists in the discipline of compound-specific isotope analysis (CSIA) for environmental and forensic investigations. Linking sources and sinks of organic contaminants is a major challenge in contemporary environmental science. Chemicals can be released to the environment when leaving their field of application, intended o ...
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11
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TERMINÉ
By the Rivers of Babylon: New Perspectives on Second Temple Judaism from Cuneiform Texts (BABYLON)
Date du début: 1 sept. 2009, Date de fin: 31 août 2015,
This project has the potential to radically change current understanding of cultic and social transformation in the post-exilic temple community of Jerusalem (c. 6th-4th centuries BCE), an important formative phase of ancient Judaism. “BABYLON” draws on recent, ground-breaking advances in the study of cuneiform texts to illuminate the Babylonian environment of the Judean exile, the socio-historica ...
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3
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TERMINÉ
Enabling information re-Use by linking clinical REsearch and CAre (EURECA)
Date du début: 1 févr. 2012, Date de fin: 31 juil. 2015,
Description
EURECA (Enabling information re-Use by linking clinical REsearch and Care) aims to enable seamless, secure, scalable and consistent linkage of healthcare information, which resides in electronic health record (EHR) systems with information in clinical research information systems, such as clinical trials. Achieving semantic inter ...
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20
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TERMINÉ
Water Harvesting Technologies Revisited: Potentials for Innovations, Improvements and Upscaling in Sub-Saharan Africa (WHATER)
Date du début: 1 janv. 2011, Date de fin: 30 juin 2015,
The WHaTeR project aims to contribute to the development of appropriate water harvesting techniques (WHTs). These WHTs should be sustainable under dynamic global and regional pressure, and strengthen rainfed agriculture, improve rural livelihood and increase food production and security in Sub-Saharan Africa. In total 3 European and 5 African organisations will be involved; namely VU University Am ...
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