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Binding-activated fluorescent DNA/peptide chimeric probes for cancer imaging (CHIMERA)
Date du début: 1 nov. 2013, Date de fin: 31 oct. 2016,
"The overriding goal of this project is to mimic Nature in the design of novel nucleic acid/peptide chimera based nanodevices that can enable cancer imaging. We will design, engineer and optimize highly specific biomolecular nanodevices that undergo binding-induced conformational changes upon target binding and, in doing so, signal the presence of the cancer marker. This scientific goal of great ...
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