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 TERMINÉ 

Ultracold Quantum Matter (UQUAM)

Date du début: 1 juil. 2013, Date de fin: 30 juin 2019,

Quantum mechanics is the basis of our understanding of the microscopic world. It is also central to the collective behaviour of matter at low temperatures, leading to unique properties that defy our classical intuition. The comprehension of such ‘quantum matter’ and the ability to master it using a newly developing set of ‘quantum technologies’ is not only of fundamental interest but holds the p ...
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 5

 TERMINÉ 

Targeting novel lipid pathways for treatment of cardiovascular disease (Athero-Flux)

Date du début: 1 sept. 2013, Date de fin: 31 août 2018,

Lipid lowering has significantly reduced cardiovascular disease (CVD) mortality in EU. However, the aim to abolish CVD in EU is far from achieved and attempts to improve on the benefits of statins with new agents have not yet delivered new therapeutics. The Consortium Athero-Flux builds on FP7-generated large-scale lipidomics data showing that specific sphingolipids and in particular distinct cer ...
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 12

 TERMINÉ 
The overall aim of the EC call is building up a scientifically literate society, which enables its citizens to participate in the research and innovation process as part of Responsible Research and Innovation (RRI). This calls for democratic citizenship education, in which two educational approaches, often presented independently in schools, are integrated, viz. Inquiry-Based Science Education (IB ...
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 21

 TERMINÉ 
Mankind is continually screening low-molecular-weight compounds from a plethora of synthetic and natural sources in the search for molecules with novel or superior pharmaceutical, agrochemical or other biological activities. In this regard, plants are a potentially rich source of bioactive molecules. Because of their extreme diversity and complex chemistry, however, plant metabolism is still under ...
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 11

 TERMINÉ 
Neuroinflammatory disease, in particular multiple sclerosis affects more than 700.000 people within Europe alone. European countries are at the forefront of neuroimmunological research and students in medicine and biology are greatly attracted by the field. Neuroimmunology research further impacts our understanding of the ethiopathology of other CNS-disorders including Alzheimer’s Dementia and Mor ...
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 13

 TERMINÉ 

Equipping the Next Generation for Active Engagement in Science (ENGAGE)

Date du début: 1 janv. 2014, Date de fin: 31 mars 2017,

The key to engaging the next generation to participate in scientific issues is to change how science is taught. Students gain an image of science as a body of content whereas RRI deals with uncertain areas of knowledge is uncertain, where values and argument matter as much as facts. The shift is hugely challenging. High stakes education systems marginalise teaching about the nature of science. Th ...
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 16

 TERMINÉ 

Nanoelectronics based on two-dimensional dichalcogenides (MoWSeS)

Date du début: 1 mars 2013, Date de fin: 28 févr. 2017,

Semiconductor industry rapidly approaches the performance limits of silicon-based CMOS technology. This proposal aims to pave the wayto electronic circuits based on two-dimensional transition metal dichalcogenides (TMDs), newly emerging semiconducting analogues ofgraphene. TMDs can be rapidly exfoliated in the liquid phase into single layers starting from powders and provide solutions of 2D materi ...
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 8

 TERMINÉ 
In acute neurodegenerative disorders, following a sudden insult, neurons are rapidly damaged and usually die but cellular loss can occur hours and days thereafter. These diseases cause massive morbidity and mortality and tremendous economic and societal burden, especially ischemic stroke, which is a leading cause of death and disability with no effective treatment to promote recovery. The brain re ...
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 10

 TERMINÉ 
IRRESISTIBLEIn the project IRRISITIBLE partners work together to make young people more aware about Responsible Research and Innovation issues. Universities and science centres will cooperate in the project using the expertise they have in linking formal land informal learning.For a long term effect the project focusses on teacher training. Each partner will form a Community of Learners in which t ...
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 14

 TERMINÉ 
EU-SOLARIS aims to create a new legal entity to explore and implement new and improved rules and procedures for reserach infrastructures (RI) for Solar Thermal Electricity (STE) technology, in order to optimise RI development and RTD coordination. According to what was communicated by ESFRI, EU-SOLARIS is expected to be the first of its kind, where Industrial needs and private funding will play a ...
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 15

 TERMINÉ 

A BLUEPRINT of Haematopoietic Epigenomes (BLUEPRINT)

Date du début: 1 oct. 2011, Date de fin: 30 sept. 2016,

In response to the call for a high impact initiative on the human epigenome, the BLUEPRINT Consortium has been formed with the aim of generating at least 100 reference epigenomes and studying them to advance and exploit knowledge of the underlying biological processes and mechanisms in health and disease. BLUEPRINT will focus on distinct types of haematopoietic cells from healthy individuals and o ...
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 45

 TERMINÉ 
The goal of the KoroiBot project is to enhance the ability of humanoid robots to walk in a dynamic and versatile fashion in the way humans do. Research and innovation work in KoroiBot will mainly target novel motion control methods for existing hardware, but it will also derive optimized design principles for next generation robots.By doing so, KoroiBot addresses the ambitious goals set for the hu ...
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 7

 TERMINÉ 

The Human Brain Project (HBP)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2016,

Understanding the human brain is one of the greatest challenges facing 21st century science. If we can rise to the challenge, we can gain profound insights into what makes us human, develop new treatments for brain diseases and build revolutionary new computing technologies. Today, for the first time, modern ICT has brought these goals within sight. The goal of the Human Brain Project, part of the ...
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 116

 TERMINÉ 

Teaching Enquiry with Mysteries Incorporated (TEMI)

Date du début: 1 févr. 2013, Date de fin: 31 juil. 2016,

The aim of this teacher training project is to help transform science and mathematics teaching practice across Europe by giving teachers new skills to engage with their students, exciting new resources and the extended support needed to effectively introduce enquiry based learning into their classrooms. We will do this by working with teacher training institutions and teacher networks across Europ ...
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 15

 TERMINÉ 
"Cancer is a complex disease involving multiple genetic and epigenetic events occurring, and influencing each other, over a long period of time. Understanding cancer, and ultimately developing effective targeted therapies, will therefore require that mutations and epigenetic alterations be systematically investigated during the multiple stages of disease development, from identifiable pre-neoplast ...
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 18

 TERMINÉ 

ASSET: Analysing and Striking the Sensitivities of Embryonal Tumours (ASSET)

Date du début: 1 nov. 2010, Date de fin: 30 avr. 2016,

Cancer is hallmarked by multiple genetic aberrations that lead to a functional derangement of cellular signalling networks. Embryonal tumours (ETs) comprising neuroblastoma, medulloblastoma and Ewing sarcoma, occur early in life, and thus may reveal pathogenetically relevant lesions clearer than adulthood tumours which carry passenger mutations accumulated during life. ASSET will exploit this fact ...
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 20

 TERMINÉ 
Primary immune deficiencies (PID) are inherited disorders of the adaptive and innate immune system marked by severe infections, autoimmunity and high risk of cancer. Treatment entails hematopoietic stem cell (HSC) transplantation from allogeneic donors, however in the absence of an HLA compatible donor, HSCT outcome is limited by delayed or suboptimal reconstitution and complications. SCID-X1 and ...
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 20

 TERMINÉ 
Traditional preclinical discovery methods, particularly for target validation, poorly predict drug efficacy, causing a high attrition rate in costly late-stage clinical trials. The PREDECT consortium will focus on complex but transferable, next generation in vitro and in vivo models for breast, prostate and lung cancers. Models will be investigated for their improved potential to validate novel th ...
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 23

 TERMINÉ 

Epigenetics towards systems biology (EPIGENESYS)

Date du début: 1 oct. 2010, Date de fin: 31 mars 2016,

The ‘EpiGeneSys’ Network of Excellence aims to enable European epigenetics research to enter the arena of systems biology, a new step forward with major implications for human health. Many diseases, not explained solely by gene mutation, have rather been associated with epigenetic disorders. Following the identification of key epigenetic regulators, a move towards a systems biology approach is nee ...
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 28

 TERMINÉ 
The BioStruct-X consortium has 19 partners from 11 EU member and associated states, who lead in facility provision and research in structural biology using high brilliance X-rays, provided by state-of-the art synchrotrons and a free electron laser. BioStruct-X will provide integrated transnational access via 42 installations in four key areas: macromolecular X-ray crystallography, small angle X-ra ...
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 20

 TERMINÉ 

Sphingolipid homeostasis: from basic biology to applications (SPHINGONET)

Date du début: 1 févr. 2012, Date de fin: 31 janv. 2016,

SPHINGONET was inspired by a common vision of its partners on the training of researchers in the field of sphingolipid homeostasis and body-wide sphingolipid signaling networks using innovative technological approaches. Dysregulation of sphingolipid balances contributes to a broad range of pathological processes, spanning neurodegeneration, asthma, autoimmune disease, insuline resistance, obesity ...
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 10

 TERMINÉ 

Virtual Embodiment and Robotic Re-Embodiment (VERE)

Date du début: 1 juin 2010, Date de fin: 31 déc. 2015,

VERE aims to carry out research on the fusion of the human body with virtual or physical surrogates. By fuse we mean that human participants would operate under the illusion that the virtual body is their own, or that they are actually in the physical space of the real world in a robotic body that they perceive as their own. As well as providing a radical extension of traditional virtual reality ...
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 17

 TERMINÉ 

Systems Biology of Colorectal Cancer (SYSCOL)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2015,

Colorectal cancer (CRC) is one of the most common cancers in both males and females, and it is perhaps the best understood of all epithelial tumors in terms of its molecular origin. Yet, despite large amount of work that has concentrated on understanding of colon tumorigenesis, we still do not know the full complement of molecular lesions that are individually necessary – and together sufficient – ...
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 11

 TERMINÉ 
Outbreaks of clinical infections affect many thousands of patients in Europe yearly. The present effective treatment for infections is large doses of systemically applied drugs. There is a high risk of recurring infections and biofilm formation for patients dependent on long term in-dwelling catheters and the extended dependency on antibiotics result in clinical drug resistance. We present a new t ...
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 7

 TERMINÉ 
Biological processes occur in space and time, but current experimental methods for systems biology are limited in their ability to resolve this spatiotemporal complexity of life. In addition, traditional “omics” methods often suffer from limited sensitivity and need to average over populations of cells at the expense of cell to cell variation. Next-generation systems biology therefore requires met ...
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 11

 TERMINÉ 
"NOTOX will develop and establish a spectrum of systems biological tools including experimental and computational methods for i) organotypic human cell cultures suitable for long term toxicity testing and ii) the identification and analysis of pathways of toxicological relevance. NOTOX will initially use available human HepaRG and primary liver cells as well as mouse small intestine cultures in 3D ...
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 13

 TERMINÉ 

Peptide-based diodes for solar cells (PEPDIODE)

Date du début: 1 août 2011, Date de fin: 31 juil. 2015,

In a solar cell that converts energy as efficient as the natural plant photosystems, electrons should travel over very short distances, through an extremely ordered structure free of traps. Guided by these principles that were worked out at WIS and CUNY, we want to synthesize many different peptides, and consecutively screen variants thereof for a putative diode function. When linked to light-harv ...
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 8

 TERMINÉ 

New approaches for the targeted therapy of Non-Small Cell Lung Cancer (LUNGTARGET)

Date du début: 1 janv. 2011, Date de fin: 30 juin 2015,

Lung cancer is the most common cancer fatality in Europe (335000 deaths/yr). Non-small cell lung cancer (NSCLC) consists 85% of the cases, with 5 yr survival
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 10

 TERMINÉ 
The PROFILES project promotes IBSE through raising the self-efficacy of science teachers and in so doing aiding a better understanding of the changing purpose of teaching science in schools and the value of stakeholder networking. The proposal innovation is in utilizing science teaching materials to support teachers, through an inspired, longitudinal training programme reflecting stakeholder views ...
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 24

 TERMINÉ 

Reconstruction Algorithms for Biological Networks (BioNetRecon)

Date du début: 1 nov. 2009, Date de fin: 30 avr. 2015,

We propose to develop reconstruction algorithms forbiological networks. Biological networks such as Phylogenies andPedigrees are key components in the mathematical analysis of evolutionand population genetics. Cellular and Metabolic networks areextensively studied in molecular genetics. We will develop algorithmsfor reconstruction of networks from data and study cases wherenetworks cannot be recon ...
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 1

 TERMINÉ 
Based on epidemiological evidence supporting an ssociation between residential exposure to extremelylow frequency magnetic fields (ELF MF) and childhood leukaemia, ELF MF have been classified as possibly carcinogenic to humans. The proposed project aims to scrutinize the underlying biophysical mechanisms andto clarify a possible causal relationship between ELF MF exposure and cancer, especially ch ...
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 9

 TERMINÉ 

Translational Kinase Tumour Inhibitor discovery Consortium (TAKTIC)

Date du début: 1 févr. 2013, Date de fin: 31 mars 2015,

Protein kinases are involved in the control of a large number of cellular processes and play a central role in human physiology. More than 500 genes encoding protein kinases have been identified in the human genome, and it is estimated that about 30% of all human proteins may be phosphorylated by kinases. Deficiency in kinase activity has implications in cancer, central nervous system disorders, a ...
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 6

 TERMINÉ 
SaveMe project will address current urgent needs for pancreatic cancer diagnosis and treatment by exploiting partners’ expertise and most recent research achievements for the design and development of novel modular nanosystems platform integrating new functionalized nano-core particles and active agents. The modular platform will enable the design of diverse active nanosystems per diagnostic or th ...
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 23

 TERMINÉ 

Advanced European Infrastructures for Detectors at Accelerators (AIDA)

Date du début: 1 févr. 2011, Date de fin: 31 janv. 2015,

AIDA (http://cern.ch/aida) addresses the upgrade, improvement and integration of key research infrastructures in Europe, developing advanced detector technologies for future particle accelerators, as well as transnational access to facilities that provide these research infrastructures.In line with the European Strategy for Particle Physics, AIDA targets the infrastructures needed for R&D, prototy ...
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 39

 TERMINÉ 
Fragmentation of research efforts, lack of a shared scientific vision and insufficient availability of research tools, shared databases, etc., is a major limitation for the understanding of atmospheric composition change over Europe under a changing climate, and the consequent inadequate transfer of prospects to the decision makers for future policies. The ACCENT-Plus project builds on the success ...
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 9

 TERMINÉ 

Systems biology towards novel chronic kidney disease diagnosis and treatment (SysKID)

Date du début: 1 janv. 2010, Date de fin: 31 déc. 2014,

Chronic kidney disease (CKD) affects up to 10% of the population. Besides eventual progression towards end stage renal disease CKD impacts the patient’s quality of life by causing serious comorbidities including cardiovascular complications and bone metabolism disorders. On the everyday clinical level early stage diagnosis and tailored treatment of CKD are still inadequate. In addition, CKD seems ...
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 30

 TERMINÉ 

Pan-European Gas-AeroSol-climate interaction Study (PEGASOS)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2014,

The Pan-European Gas-AeroSOls-climate interaction Study (PEGASOS) European large scale integrating project brings together most of the leading European research groups, with state-of the-art observational and modeling facilities to:(1) Quantify the magnitude of regional to global feedbacks between atmospheric chemistry and a changing climate and to reduce the corresponding uncertainty of the major ...
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 27

 TERMINÉ 
OPTS project aims at developing a new Thermal Energy Storage (TES) system based on single tank configuration using stratifying Molten Salts (MS, Sodium/Potassium Nitrates 60/40 w/w) as heat storage medium at 550°C maximum temperature, integrated with a Steam Generator (SG), to provide efficient, reliable and economic energy storage for the next generation of trough and tower plants.The three-year ...
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 11

 TERMINÉ 

Transport and signalling in Polarized Cells (TRANSPOL)

Date du début: 1 déc. 2010, Date de fin: 30 nov. 2014,

"Aberrant molecular signalling and intracellular trafficking are the molecular cause of many human diseases. TRANSPOL is an interdisciplinary initial stage training network (ITN) at the intersection of cell/molecular biology and membrane physics aimed specifically at the molecular understanding of the functional relationship between intracellular trafficking and cellular signalling and their relev ...
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 11

 TERMINÉ 

Dynamic Molecular Nanostructures (DYNAMOL)

Date du début: 1 nov. 2010, Date de fin: 31 oct. 2014,

The ITN DYNAMOL will establish a powerful new approach for the preparation of nanostructures based on dynamic covalent chemistry. This approach combines the advantages of covalent synthesis (robustness of bonds) with those of non-covalent synthesis (error correction, responsiveness) without any of the disadvantages. It therefore has the potential to provide unique solutions for several important c ...
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 13