3 projets européens trouvés
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TERMINÉ
HEPATIC MICROFLUIDIC BIOREACTOR (HEMIBIO)
Date du début: 1 janv. 2011, Date de fin: 31 déc. 2015,
The goal of HeMiBio is to develop a hepatic microfluidic bioreactor from human iPSC-derived hepatocytes, hepatic sinusoidal endothelial cells (HSEC) and stellate cells (HSC), suitable for inclusion in a repeated dose toxicity testing strategy of pharmaceuticals/cosmetic ingredients. The successful creation of such a liver-device requires (a) homotypic and heterotypic interactions between the three ...
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13
Participants partenaires
TERMINÉ
Bottom-up reconstitution of a biomimetic bioartificial liver (RE-LIVER)
Date du début: 1 juil. 2012, Date de fin: 30 juin 2015,
The liver, by way of its central role in both endogenous and exogenous metabolism, is one of the most well-studied organs in the human body.Hepatic tissue and its derivatives have a wide range of in-vivo and in-vitro applications from whole organ or partial lobe transplant, bioartificial ex-vivo devices, treatment of metabolic disorders to toxicology, drug metabolism and tissue regeneration. On th ...
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5
Participants partenaires
TERMINÉ
Construction kit for tailor-made vascularized boneimplants (VascuBone)
Date du début: 1 janv. 2010, Date de fin: 31 mars 2015,
The goal of VascuBone is to develop a “tool box” for bone regeneration, which on one hand fulfils basic requirements and on the other hand is freely combinable with what is needed in the respective patient’s situation. The tool box will include a variation of biocompatible biomaterials and cell types, FDA approved growth factors, material modification technologies, simulation and analytical tools ...
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