5 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Solving an evolutionary jigsaw puzzle: A next-generation genomics approach to trace the origins of the eukaryotic cell (PUZZLE_CELL)
Date du début: 1 nov. 2012, Date de fin: 31 oct. 2017,
The origin of the eukaryotic cell represents an enigmatic yet dramatically incomplete evolutionary puzzle. The few pieces of this puzzle that we have managed to identify thus far indicate that the eukaryotic cell most probably emerged via a fusion of an archaeal and an alphaproteobacterial cell. Yet, beyond this, scientific debate is mainly engulfed by speculation, which, to a large extent, is fed ...
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TERMINÉ
Harnessing Proto-Enzymes for Novel Catalytic Functions (COMPENZYMEEVOLUTION)
Date du début: 1 oct. 2012, Date de fin: 30 sept. 2017,
Enzymes are Nature’s catalysts, reducing the timescales of the chemical reactions that drive life from millions of years to seconds. There is also great scope for enzymes as biocatalysts outside the cell, from therapeutic and synthetic applications, to bioremediation and even for the generation of novel biofuels. Recent years have seen several impressive breakthroughs in the design of artificial e ...
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TERMINÉ
Shedding light on the diversity, ecology and evolution of enigmatic, uncultivated archaea using novel single cell and metagenomics approaches (EnigmaArchaea)
Date du début: 1 oct. 2014, Date de fin: 30 sept. 2016,
The Archaea represent the Third Domain of Life and comprise a group of microorganisms that are important players in major biogeochemical cycles. Yet, even though more than 30 years have passed since their discovery, the biology, lifestyle and diversity of the archaeal domain of life remain to be poorly understood thus far, especially when compared to that of Bacteria and eukaryotes.Recent environ ...
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TERMINÉ
Single-cell phylogenomic exploration of archaeal dark matter (DARKCELLS)
Date du début: 1 avr. 2014, Date de fin: 31 mars 2016,
While the archaeal domain of life was discovered more than 30 years ago, the biology of archaeal organisms remains to be relatively obscure, especially when compared to that of bacterial and eukaryotic life. Yet, despite the limited knowledge regarding their lifestyle and ecological relevance, evidence is mounting that certain archaea play key roles in global nitrogen and carbon cycles. In additio ...
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TERMINÉ
FROM PATIENT DATA TO PERSONALISED HEALTHCARE IN ALZHEIMER'S DISEASE (PredictAD)
Date du début: 1 juin 2008, Date de fin: 30 nov. 2011,
Dementia causes long and oppressive suffering to patients and their relatives and imposes enormous costs on society. About 25 million people suffered from dementia in 2000. As a 4-fold increase of this number is expected by 2050, dementia is one main health issue of the next decades. Alzheimer's disease (AD) covers 60-70% of all dementia cases. No cure for AD exists, and effective and reliable ear ...
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