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Molecular mechanism of amyloid β aggregation (MAMBA)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,

"Generation of toxic oligomers during aggregation of amyloid beta peptide (Abeta42) into amyloid fibrils is a central event in Alzheimer disease. Understanding the aggregation process is therefore one important step towards therapy and diagnosis of the disease. We propose a physical chemistry approach with the goal of finding the molecular mechanisms behind the process in terms of the underlying m ...
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