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 TERMINÉ 
Our main objective is to identify determinants of brain, cognitive and mental health at different stages of life. By integration, harmonisation and enrichment of major European neuroimaging studies of age differences and changes, we will obtain an unparalleled database of fine-grained brain, cognitive and mental health measures of more than 6.000 individuals. Longitudinal brain imaging, genetic an ...
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 16

 TERMINÉ 
Sudden cardiac arrest (SCA) causes ~20% of all deaths in Europe. SCA is lethal within minutes if left untreated and survival rates are presently only 5-20%. Therefore, there is a large medical need to improve SCA prevention and treatment. Designing effective individualized prevention and treatment strategies requires knowledge on genetic and environmental risk factors. So far, these efforts have b ...
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 17

 TERMINÉ 
GLORIA aims to prove that the addition of chronic low dose glucocorticoids (GC) to current antirheumatic therapy is highly cost-effective and safe in elderly patients with rheumatoid arthritis (RA). RA is a frequent (affecting > 2% of the elderly population), painful and disabling chronic disease with high societal costs. RA is associated with multiple comorbidities, polypharmacy and adverse event ...
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 13

 TERMINÉ 
Myelodysplastic syndromes (MDS) are chronic bone marrow malignancies of the elderly, complicated by severe anaemia. MDS significantly affects quality-adjusted survival and it imposes an increasing financial burden on patients and healthcare (HC) systems. The burden of disease is expected to worsen in the future, given the aging EU population and newly identified MDS cases among those diagnosed wit ...
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 16

 TERMINÉ 

Interdisciplinary Network for Dementia Utilising Current Technology (INDUCT) (INDUCT)

Date du début: 1 mars 2016, Date de fin: 29 févr. 2020,

Dementia raises complex challenges for people with dementia, their families, and society. The European Parliament has called for investment in high quality, innovative technology research to improve dementia care but so far there has been little benefit because research has generally been limited, small scale and methodologically flawed. In particular: the poor understanding between research and b ...
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 9

 TERMINÉ 
Major depressive disorder, dementia, anxiety disorders, and substance abuse affect a substantial part of the European older population. Over 70% of Europeans reside in cities, and this percentage will increase in the next decades. Urbanization and ageing have enormous implications for public mental health. Cities pose major challenges for older citizens, but also offer opportunities for the design ...
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 14

 TERMINÉ 

Viruses, Immune stimulation and RNA Interference in Oncology Network (VIRION)

Date du début: 1 oct. 2015, Date de fin: 30 sept. 2019,

The Viruses, Immune stimulation and RNA Interference in Oncology Network (VIRION) is focused on the execution of an internationally competitive cancer research project focused on the development of a novel therapeutic regime by combining immune therapy with oncolytic virotherapy and RNA interference techniques. Recent clinical successes have shown the immune system to be a powerful ally in the fig ...
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 4

 TERMINÉ 
"Cancers of the Head and Neck Region (HNC) are the 6th more deadly cancers worldwide: in Europe ~150.000 new cases are detected and ~70.000 patients die every year. The main reasons for high mortality are the fact that the majority of cases are diagnosed in advanced Stage and the intrinsic heterogeneity of such tumors. At present the only adopted treatment decision method is based on TNM (Tumor-ly ...
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 13

 TERMINÉ 

Sustainable tailored integrated care for older people in Europe (SUSTAIN)

Date du début: 1 avr. 2015, Date de fin: 31 mars 2019,

The overall aims of SUSTAIN are twofold: 1. to improve established integrated care initiatives for older people living at home with multiple health and social care needs, ensuring they are patient-centred, prevention oriented, efficient, resilient to crises, safe and sustainable; 2. to ensure that improvements to the integrated care initiatives are applicable and adaptable to other health systems ...
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 15

 TERMINÉ 
MooDFOOD is a Multi-country cOllaborative project on the rOle of Diet, Food-related behaviour, and Obesity in the prevention of Depression. Depression is one of the most prevalent, severe and disabling disorders in the EU and places a heavy burden on individuals and families. A large proportion of the EU population is overweight which increases depression risk. Improving food-related behaviour and ...
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 17

 TERMINÉ 
IMMUNOSHAPE aims at training a new generation of scientists that will be capable of combining state of the art synthesis and screening technology to develop new lead structures for highly selective glycan based multivalent immunotherapeutics for the treatment of cancer, autoimmune diseases and allergy. To this end, we have set up a training program in a unique academic-industrial environment that ...
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 17

 TERMINÉ 

Personalized PREvention of Chronic DIseases (PRECeDI)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2018,

The aim of the Personalized pREvention of Chronic DIseases consortium (PRECeDI) is to provide high-quality, multidisciplinary knowledge through training and research in Personalized Medicine (PM), with specific reference to prevention of chronic diseases. There is a large consensus that PM is a driver of innovation for research and health care, and also for the health care system and industry as a ...
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 10

 TERMINÉ 
Important progress has been made in the field of HPV-disease prevention with the development and implementation of HPV vaccines and HPV DNA screening. In the CoheaHr project, the (cost-) effectiveness of different European preventive strategies will be compared. The goal is to build a reliable and comparable evidence base on the (cost-) effectiveness of these policies implemented under country-spe ...
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 13

 TERMINÉ 
Survival rates after childhood cancer now reach nearly 80% in developed European countries as a result of more effective therapies and better supportive care, leading to a steady increase in the number of survivors in the population. However, the treatments that have improved survival are harsh and cause serious side-effects that can greatly impact survivors’ quality of life in the long term. The ...
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 19

 TERMINÉ 

From Patient Data to Clinical Diagnosis in Neurodegenerative Diseases (PredictND)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,

Dementia is a growing health problem with enormous costs to society: the costs currently equal 1% of the global gross-domestic product and a three-fold increase to 115 million dementia cases is expected by 2050. Addressing this grave human and economic challenge requires efficient solutions that do not exist yet: tools to detect and diagnose persons at an early phase, and interventions for delayin ...
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 10

 TERMINÉ 
Patients with diabetes are at risk of developing diabetic nephropathy, which will ultimately result in the requirement for renal replacement therapy and is also associated with high cardiovascular morbidity and mortality. Detection of low concentrations of albuminuria in urine (microalbuminuria) is the current clinical standard for detecting those at significant risk and targeting preventive treat ...
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 21

 TERMINÉ 
With 13,000 deaths each year in the EU, cervical cancer (CC) is one of the deadliest cancers worldwide. This is unnecessary, since CC is well detectable and treatable at early stages. For this reason, most EU countries have screening programs in place. These screening programs have had (varying) success in reducing CC incidence, however, this reduction has reached a plateau and new strategies are ...
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 1

 TERMINÉ 
Vitamin D deficiency has significant implications for human health and impacts on healthy growth and development and successful aging. Fundamental knowledge gaps are barriers to implementing a safe and effective public health strategy to prevent vitamin D deficiency and optimize status. ODIN will provide the evidence to prevent vitamin D deficiency in Europe and improve nutrition and public health ...
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 32

 TERMINÉ 

Equipping European Primary Care Health Professionals to Deal with Genetics

Date du début: 1 sept. 2014, Date de fin: 31 août 2017,

With one person in 20 being affected by a genetic condition in their lifetime, medical professionals in primary care are increasingly expected to deliver genetic services in daily patient care. Professionals in primary care are increasingly expected to answer patient queries about genetic conditions, deliver genetic information and triage patients who require genetic or other specialist services ...
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 7

 TERMINÉ 

Network Neurodegeneration in Alzheimer's Disease (NOMAD)

Date du début: 7 avr. 2014, Date de fin: 6 avr. 2017,

Alzheimer’s disease (AD) is a highly prevalent neurodegenerative disease associated with gradual loss of cognitive functions and brain vitality. The leading “amyloid cascade” hypothesis for the pathogenesis of AD states that amyloid-β (Aβ) starts to accumulate ~15 years before symptom onset and starts a cascade of pathological events, including aggregation of tau. It is known (mainly from post-mor ...
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 2

 TERMINÉ 
The MastermMind Consortium to avoid dispersing efforts has narrowed the scope of the services to just one, non-organic, mental disorder: depression. This because of its high incidence, social cost and proven clinical effectiveness of ICT in its treatment. MasterMind intends: 1) to implement at scale (almost 5.000 patient overall) evidence based computerised Cognitive Behavioural Therapy (cCBT) ser ...
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 23

 TERMINÉ 
The proposed project is an interdisciplinary effort of specialists from water management and ICT research respectively to develop an intelligent Integrated Support System for Efficient WATer USage and resources management (ISS-EWATUS). The project will develop several innovative ICT methods aiming to exploitthe untapped water-saving potential in EU. The overall goal will be achieved by developing ...
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 10

 TERMINÉ 

European-COMPARative Effectiveness research on online Depression (E-COMPARED)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2016,

In 2010, 30 million Europeans were affected by depression and their number is still growing. Half of Europeans in need of mental care for depression do not have access to care services, do not always receive evidence-based treatments, are confronted with long waiting lists or high care expenditures. Internet-based treatment has the potential to addresses the drawbacks of standard care and keep dep ...
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 16

 TERMINÉ 

Phonon-Assisted Processes for Energy Transfer and Sensing (PAPETS)

Date du début: 1 sept. 2013, Date de fin: 30 nov. 2016,

There is mounting experimental and theoretical evidence that suggests that coherent electronic and vibrational dynamics are essential to understand physiological processes. This project addresses this newly emerging frontier between biology and quantum physics by aiming to determine the role of coherent vibrational dynamics in the efficiency of energy storage in natural and artificial light harves ...
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 8

 TERMINÉ 
MiRacle focuses on the development of a therapeutic formulation for the treatment of head and neck cancer. Head and neck cancer contributes to approximately 5% of all cancers in the Western world. Unfortunately the majority of H&N cancer patients present with advanced stages of disease. These patients frequently develop locoregional recurrences, distant metastasis and/or second primary tumors resu ...
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 9

 TERMINÉ 

Innovative Radiochemistry to Advance Molecular Imaging (RADIOMI)

Date du début: 1 nov. 2012, Date de fin: 31 oct. 2016,

The RADIOMI Initial Training Network (ITN) has the goal of providing training in a superbly suited academic and industrial environment uniquely equipped to conduct a scientific research program that addresses one of the key aspects of functional imaging, the underpinning radiochemistry essential for preparation of radiotracers currently difficult or not possible to access. This will be exploited f ...
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 9

 TERMINÉ 
Large full-thickness skin defects resulting from burns, soft tissue trauma, congenital giant nevi, tumour resection, and disease leading to skin necrosis, represent a significant and common clinical problem worldwide. This problem is far from being solved. The main challenge encountered is that most autologous skin grafting techniques are based on transplanting split-thickness skin (the today’s go ...
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 11

 TERMINÉ 

The Human Brain Project (HBP)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2016,

Understanding the human brain is one of the greatest challenges facing 21st century science. If we can rise to the challenge, we can gain profound insights into what makes us human, develop new treatments for brain diseases and build revolutionary new computing technologies. Today, for the first time, modern ICT has brought these goals within sight. The goal of the Human Brain Project, part of the ...
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 116

 TERMINÉ 
Description OraMod project: Helping clinicians predict oral cavity cancer reoccurrenceGenomic markers and computer models can predict the reoccurance of oral cavity cancer. But these innovative diagnostic technologies are currently stuck in labs and are not being used by clinicians in hospitals. The EU-funded project OraMod, led by the Un ...
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 9

 TERMINÉ 

The MEtabolic Road to DIAstolic Heart Failure (MEDIA)

Date du début: 1 janv. 2011, Date de fin: 30 juin 2016,

More than 50% of heart failure (HF) patients present without a major deficit of left ventricular (LV) systolic function and are presumed to suffer from diastolic HF (DHF) because diastolic LV distensibility is usually impaired in these patients. The vast majority (~80%) of DHF patients is exposed to metabolic risk factors. The MEDIA consortium therefore investigates:1) how metabolic derangements c ...
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 23

 TERMINÉ 

Europeana Cloud: Unlocking Europe's Research via The Cloud (eCloud)

Date du début: 1 févr. 2013, Date de fin: 30 avr. 2016,

Europeana Cloud is a Best Practice Network, submitted under Objective 2.1.a and coordinated by the Europeana Foundation, designed to establish a cloud-based system for Europeana and its aggregators. Europeana Cloud will provide new content, new metadata, a new linked storage system, new tools and services for researchers and a new platform - Europeana Research. Content providers and aggregators, a ...
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 36

 TERMINÉ 
The volume of news data is enormous and expanding, covering billions of archived documents and millions of documents as daily streams, while at the same time getting more and more interconnected with knowledge provided elsewhere. Professional decision-makers that need to respond quickly to new developments and knowledge or that need to explain these developments on the basis of the past are faced ...
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 7

 TERMINÉ 

Enabling information re-Use by linking clinical REsearch and CAre (EURECA)

Date du début: 1 févr. 2012, Date de fin: 31 juil. 2015,

Description EURECA (Enabling information re-Use by linking clinical REsearch and Care) aims to enable seamless, secure, scalable and consistent linkage of healthcare information, which resides in electronic health record (EHR) systems with information in clinical research information systems, such as clinical trials. Achieving semantic inter ...
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 20

 TERMINÉ 
Unprecedented growth in the accessibility of imaging data of persons with brain diseases has led to the development of computational infrastructures offering scientists access to image databases and e-Science services. FP7 neuGRID is the leading e-Infrastructure where neuroscientists can find core services and resources for brain image analysis. "neuGRID for Users" (N4U) will provide an e-Science ...
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 14

 TERMINÉ 
Over the past decade we are witnessing an ever-increasing amount of cyberattacks on the Internet.Prolific, ingenious, and ranging in style from large-scale worms to "below the radar" phishing attempts, cyberattacks have evolved to unprecedented levels of sophistication. To counter these cyberattacks, defenders are (mostly) developing safeguards, after the attack was made. In the meantime, while de ...
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 10

 TERMINÉ 

Open Polarity Enhanced Named Entity Recognition (OpeNER)

Date du début: 1 juil. 2012, Date de fin: 30 juin 2014,

Currently there are a multitude of companies offering Content Analytics and Social Internet Mining services for the purposes of Opinion Mining and Sentiment Analysis. Truly effective Sentiment Analysis is a complex NLP task in monolingual contexts alone. In multilingual contexts the complexity increase many-fold and also presents the challenge of comparison of opinion across languages and cultures ...
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 7

 TERMINÉ 

The Hand Embodied (THE)

Date du début: 1 mars 2010, Date de fin: 31 mai 2014,

Description Advancing the state of the art in artificial system architectures for the "hand" as a cognitive organ The scientific goals of The Hand Embodied concern the reciprocal linkages between the physical hand and its high-level control functions, and about the way that the embodiment enables ...
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 11

 TERMINÉ 

ViSTA-TV - Video Stream Analytics for Viewers in the TV Industry (ViSTA-TV)

Date du début: 1 juin 2012, Date de fin: 31 mai 2014,

Live video content is increasingly consumed over IP networks in addition to traditional broadcasting. The move to IP provides a huge opportunity to discover what people are watching in much greater breadth and depth than currently possible through interviews or set-top box based data gathering by rating organizations, because it allows direct analysis of consumer behavior via the logs they produce ...
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 8

 TERMINÉ 

Open Computing Infrastructures for Elastic Services (CONTRAIL)

Date du début: 1 oct. 2010, Date de fin: 31 janv. 2014,

In the future of corporate IT, companies will rely on highly dynamic distributed IT infrastructures. Federation models are envisioned where a given organisation will be both a Cloud provider during periods when its IT infrastructure is not used at its maximal capacity, and a Cloud customer in periods of peak activity.The main contribution of CONTRAIL will be the development of an integrated appro ...
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 10

 TERMINÉ 

Virtual Biodiversity Research and Access Network for Taxonomy (ViBRANT)

Date du début: 1 déc. 2010, Date de fin: 30 nov. 2013,

Biodiversity science brings information science and technologies to bear on the data and information generated by the study of organisms, their genes, and their interactions. ViBRANT will help focus the collective output of biodiversity science, making it more transparent, accountable, and accessible. Mobilising these data will address global environmental challenges, contribute to sustainable dev ...
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