8 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
PROMOTING ACTIVE AGEING: FUNCTIONAL NANOSTRUCTURES FOR ALZHEIMER’S DISEASE AT ULTRA-EARLY STAGES. (PANA)
Date du début: 1 mars 2016, Date de fin: 28 févr. 2021,
Alzheimer’s disease (AD) is the leading cause of dementia and loss of autonomy in the elderly, implying a progressive cognitive decline and limitation of social activities. Progressive aging of EU population will increase the magnitude of this problem in the next decades. Currently, there is not an effective method for the early diagnosis of AD. Therefore, there is an urgent need to develop new ef ...
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11
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TERMINÉ
Blood test for clinical therapy guidance of non-small cell lung cancer patients (LungCARD)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
Lung cancer is the most common cancer worldwide. NSCLC alone make up about 75% of all lung cancers and most hospitals currently test all NSCLC patients for EGFR mutations (pharmacogenomics) for treatment decision (personalised medicine) – i.e., patients with mutation(s) in EGFR gene should receive a EGFR-Tyrosine Kinase Inhibitor (TKI) drug (e.g. afitinib) treatment; while those that do not presen ...
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8
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TERMINÉ
Extracellular brain proteolysis in neuronal plasticity and neuropsychiatric disorders (EXTRABRAIN)
Date du début: 1 sept. 2013, Date de fin: 31 août 2017,
...e emerged as a highly topical research area, also because their extracellular localization makes the development of enzymatic inhibitors more feasible. This proposal brings together a group of well-established academic and industrial partners sharing interest in the ECM and its proteolysis. In the proposal there is clearly an overlapping interest in specific brain conditions and structures to be ...
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9
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TERMINÉ
Demonstration Activities for the clinical validation of the prototype HILYSENS Lab-on-a-Chip (HILYSENS II)
Date du début: 1 avr. 2014, Date de fin: 31 mars 2016,
HILYSENS II is based on the 2-year HILYSENS research and development project (started November 2010) funded by the ‘Research for the Benefit of SMEs’ program of the European Commission's Seventh Framework Programme (FP7). HILYSENS II proposes Demonstration Activities for the prototype HILYSENS Lab-on-a-Chip developed during the successful research and development project, which was designed as a s ...
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5
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TERMINÉ
CERTIFIED PACKS FOR EASIER NEXT-GENERATION SEQUENCING CLINICAL DIAGNOSTICS (easierNGS)
Date du début: 1 oct. 2014, Date de fin: 28 févr. 2015,
Next-generation sequencing (NGS) has revolutionized genomic research by drastically decreasing the cost of sequencing and increasing the throughput of generated data, but still has not been able to reach its implementation in clinical diagnostic laboratories where there is a huge potential market application for it. The current market gold-standard in clinical diagnostic (i.e. Sanger-based sequenc ...
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1
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TERMINÉ
Point-of-care blood device for fast and reliable prediction of drug response in non- small-cell lung carcinoma patients from blood samples (LungCARD)
Date du début: 7 févr. 2013, Date de fin: 6 févr. 2015,
Chemotherapy is the standard care for the treatment of non-small cell lung carcinoma (NSCLC) patients, however most of non-small cell lung cancer tumours are not sensitive to this treatment. As an alternative to chemoterapy, target therapy with gefitinib (epidermal growth factor receptor-tyrosine kinase inhibitor) has been used in clinical practice in patients with tumours harbouring mutations in ...
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7
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TERMINÉ
NANOPARTICLES FOR THERAPY AND DIAGNOSIS OF ALZHEIMER DISEASE (NAD)
Date du début: 1 sept. 2008, Date de fin: 31 août 2013,
... transcytotic route. Several artificial and cellular models will be used to fine-tune such features and to improve NPs biocompatibility, non-immunogenicity, non-toxicity and physical stability. Eventually, absorption, distribution, metabolism and excretion will be studied using animal models of AD. Different routes (i.v., oral, nasal) and protocols (two-step, NPs cocktails, aerosols) of administra ...
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19
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TERMINÉ
Highly sensitive and specific low-cost lab-on-a-chip system for Lyme disease diagnosis (HILYSENS)
Date du début: 1 nov. 2010, Date de fin: 28 févr. 2013,
"The aim of HILYSENS is to develop a novel lab-on-chip diagnostic tool to improve clinical diagnostic, disease monitoring and treatment of Lyme Disease by enabling specific and sensitive detection of the human serological response against its causative agent Borrelia burgdoferi infections. Lyme Disease is the most common tick-borne infection in Europe with around 85,000 new cases per year and its ...
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