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17 projets européens trouvés

Recherche sur 125080 projets européens

 TERMINÉ 

DARIAH ERIC Sustainability Refined (DESIR)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2019,

Europe has a long and rich tradition as a centre for the arts and humanities. However, the digital transformation poses challenges to the arts and humanities research landscape all over the world. Responding to these challenges the Digital Research Infrastructure for Arts and Humanities (DARIAH) was launched as a pan-European network and research infrastructure. After expansion and consolidation, ...
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 18

 TERMINÉ 

ELIXIR-EXCELERATE: Fast-track ELIXIR implementation and drive early user exploitation across the life-sciences. (ELIXIR-EXCELERATE)

Date du début: 1 sept. 2015, Date de fin: 31 août 2019,

...the most complex and heterogeneous datasets that science can currently imagine, with unprecedented volumes of biological data to manage.Data will only generate long-term value if it is Findable, Accessible, Interoperable and Re-usable (FAIR). This requires a scalable infrastructure that connects local, national and European efforts and provides standards, tools and training for data stewardship.Fo ...
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 47

 TERMINÉ 

PhenoMeNal: A comprehensive and standardised e-infrastructure for analysing medical metabolic phenotype data (PhenoMeNal)

Date du début: 1 sept. 2015, Date de fin: 31 août 2018,

In the coming decade a significant number of the 500.000.000 European (EU/EEA) citizens will have their genome determined routinely. This will be complemented with much cheaper (currently ~20 Euro per measurement) acquisition of the metabolome of biofluids (e.g. urine, saliva, blood plasma) which will link the genotype with metabolome data that captures the highly dynamic phenome and exposome of p ...
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 17

 TERMINÉ 

SYSTEMS GLYCOBIOLOGY OF GASTRIC CANCER (GASTRICGLYCOEXPLORER)

Date du début: 1 mai 2013, Date de fin: 30 avr. 2018,

This ITN is built around the biological question of O-glycosylation in gastric cancer for training in systems glycobiology. For meeting the needs of the research goal and for training for future systems glycobiology operations, cross disciplinary international institutes have been identified with top level state-of-the-art glycobioanalytical, glycotechnological and glycobioinformatics platforms. T ...
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 13

 TERMINÉ 

Human Brain Project Specific Grant Agreement 1 (HBP SGA1)

Date du début: 1 avr. 2016, Date de fin: 31 mars 2018,

Understanding the human brain is one of the greatest scientific challenges of our time. Such an understanding can provide profound insights into our humanity, leading to fundamentally new computing technologies, and transforming the diagnosis and treatment of brain disorders. Modern ICT brings this prospect within reach. The HBP Flagship Initiative (HBP) thus proposes a unique strategy that uses I ...
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 126

 TERMINÉ 

Systems Biology to Identify Molecular Targets for Vascular Disease Treatment (SYSVASC)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,

...established cardiovascular disease (CVD) animal models and patient cohorts. The coordinated application of these tools and know-how will identify pathophysiological mechanisms and key molecules responsible for onset and progression of CVD and validate their potential to serve as molecular targets for therapeutic intervention. To this end, the consortium will also use unique resources to evaluate m ...
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 19

 TERMINÉ 

SYSTEMS BIOLOGY OF PATHWAYS INVOLVING BRAIN AGEING (AGEDBRAINSYSBIO)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

...ng in subregion of a neuron (such as dendrites and dendritic spines), (3) the inclusion of these experimentally validated networks in larger networks obtained from available databases to extend possible protein interactions, (4) the identification of human and/or primate positive selection either in coding or in regulatory gene sequences,(5) the manipulation of these human and/or primate acceler ...
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 15

 TERMINÉ 

The Open Pharmacological Concepts Triple Store (OPEN PHACTS)

Date du début: 1 mars 2011, Date de fin: 29 févr. 2016,

...and chemogenomics will be developed creating a comprehensive Systems Chemical Biology Analysis Network. Security issues around proprietary data, shared via the Open PHACTS Discovery Platform and accessible for safe querying and reasoning will be properly addressed with expert trusted parties.The Open PHACTS consortium comprises 20 European academic and SME partners, with leading experts in the fie ...
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 32

 TERMINÉ 

Integrating chemical approaches to treat pancreatic cancer: making new leads for a cure (Panacreas)

Date du début: 1 mars 2011, Date de fin: 29 févr. 2016,

Pancreatic ductal adenocarcinoma (PDAC) causes 34000 deaths in the EU every year. Conventional cancer treatments have close to no impact on this disease. As a result, almost all patients diagnosed with PDAC develop metastases and eventually die. Given this poor outlook, the search for new therapeutics is mandatory. These will have to target relevant cancer pathways and be designed based on the ava ...
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 12

 TERMINÉ 

Improving beta-cell function and identification of diagnostic biomarkers for treatment monitoring in diabetes (IMIDIA)

Date du début: 1 févr. 2010, Date de fin: 30 sept. 2015,

An absolute or relative loss of beta-cell mass and function underlie the development of type I and type 2 diabetes.Preventing beta-cell demise or restoring their number and function is a major therapeutic goal. However,development of novel diagnostic and prognostic tools, and of novel therapeutic modalities, is hampered by the limited knowledge of the molecular pathways that control beta-cell demi ...
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 23

 TERMINÉ 

Modelling and predicting sensitivity to targeted therapies in colorectal cancers (COLTHERES)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2014,

Effective and long term treatment of cancer is now in sight, but will ultimately require an increasingly ‘personalised’ approach where the ‘right’ combination of drugs will be administered to the ‘right’ patients, based on a detailed understanding of their genetic background and their co-associated sensitivity or resistance ‘biomarkers’. Efforts are specifically required to identify validated risk ...
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 11

 TERMINÉ 

Broadening the Bioinformatics Infrastructure to unicellular, animal, and plant science (ALLBIO)

Date du début: 1 oct. 2011, Date de fin: 30 sept. 2014,

The main aim of AllBio will be the coordination of the partner's activities that are aimed at the extension of a large number of bioinformatics facilities towards applicability in target life science areas beyond human health. Bioinformatics facilities developed for the human health area will be extensively tested on unicellular (incl. bacterial), plant and (farm) animal genomes, and they will be ...
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 11

 TERMINÉ 

International Data Exchange and Data Representation Standards for Proteomics (ProteomeXchange)

Date du début: 1 janv. 2011, Date de fin: 30 juin 2014,

...ngle point of data submission to the user; (ii) to ensure data availability in all of the different member databases; (iii) to use community standard formats to represent the data, so it becomes accessible to all regardless of data origin; (iv) to provide added value through different views on the same data, from repositories to derived search tools.With an international consortium and support fro ...
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 13

 TERMINÉ 

The Microme Project: A Knowledge-Based Bioinformatics Framework for Microbial Pathway Genomics (Microme)

Date du début: 1 déc. 2009, Date de fin: 30 nov. 2013,

...ctly into the flow of newly sequenced genomes, will allow a qualitative increase in the speed and reliability of the pathway generation process. Pathways and models produced the pipeline will be accessible to the scientific community as an integrated resource via the Microme portal. Finally, taking advantage of the availability of pathway assemblies from a large sample of genomes, methods for comp ...
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 16

 TERMINÉ 

Proteomics Standards International Molecular Exchange - Systematic Capture of Published Molecular Interaction Data (PSIMEx)

Date du début: 1 mars 2009, Date de fin: 31 août 2013,

The aim of the PSIMEx proposal is to systematically make published molecular interaction data computationally accessible. We plan to further develop the existing standard for molecular interactions developed by the HUPO Proteomics Standards Initiative, and to promote its implementation in the entire chain from experiment planning via data formatting and analysis to data representation in journal p ...
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 15

 TERMINÉ 

Genotype-To-Phenotype Databases: A Holistic Solution (GEN2PHEN)

Date du début: 1 janv. 2008, Date de fin: 30 juin 2013,

"The GEN2PHEN project aims to unify human and model organism genetic variation databases towards increasingly holistic views into Genotype-To-Phenotype (G2P) data, and to link this system into other biomedical knowledge sources via genome browser functionality. The project will establish the technological building-blocks needed for the evolution of today’s diverse G2P databases into a future seaml ...
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 23

 TERMINÉ 

European Life-science Infrastructure for Biological Information (ELIXIR)

Date du début: 1 nov. 2007, Date de fin: 31 déc. 2012,

...will include:A Holding stakeholder meetings to bring together national representatives, key scientific opinion and funding organisations.B Establishing working parties, supported by technical feasibility studies where appropriate, to address the tasks and issues above with final reports at month 18.C Consolidating these reports into a management and funding proposal to be sent to member states an ...
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 33