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 TERMINÉ 

DISKOmice (DISKOMICE)

Date du début: 1 sept. 2012, Date de fin: 30 août 2016,

We hypothesize that within the intervertebral disc (IVD), a niche exists comprising the nucleus pulposus and the inner layer of the annulus fibrosus and the cartilage endplate. In the niche, two events govern successful maintenance of disc cell function: the ability of progenitor cells to provide replacement cells, and the power of this cell population for renewal. In the disc niche, environmenta ...
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 TERMINÉ 
ALLOW THE YOUTH MOBILITY BY UPGRADING SKILLS ACQUIRED THROUGH LEARNING MADE WITHIN THE EUROPEAN SPACE The Regional Federation of MFR (FRMFR) in Brittany undertakes, in its mission of facilitating networks, eight MFR located throughout the Breton territory. The 161 young people involved in the Erasmus + program will go to twelve different countries: Switzerland, Ireland, Spain, Sweden, Poland, Port ...
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 TERMINÉ 
In the growing population of patients with congenital heart defects (CHD), while arrhythmias are not a major issue for children, they are a leading complication during adulthood. My hypothesis is that the origin of some life-threatening arrhythmias in adult, lies in cardiac structural and electrophysiological development. Thus, studying causes of CHDs may reveal key steps, mis-regulated in adult p ...
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 2

 TERMINÉ 
The dynamic modulation of ion channels is crucial to the regulation of cardiac excitability and defects in channel modulation, associated with congenital and acquired cardiac diseases, lead to the development of life threatening arrhythmias. The dynamic modulation of functional expression of ion channels is achieved through changes in cell surface expression and/or functioning of pore-forming chan ...
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 1