3 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Parasite-specific cyclic nucleotide phosphodiesterase inhibitors to target Neglected Parasitic Diseases (PDE4NPD)
Date du début: 1 mars 2014, Date de fin: 28 févr. 2018,
This project aims to unite global efforts to target the highly druggable class of enzymes called cyclic nucleotide phosphodiesterases (PDEs) in the fight for neglected parasitic diseases (NPD). It will establish a drug discovery platform, PDE4NPD, that combines phenotypic screening with efficient target-centric drug discovery, including target validation, various strategies for compound screening, ...
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11
Participants partenaires
TERMINÉ
Unbiased Biomarkers for the Prediction of Respiratory Disease Outcomes (U-BIOPRED)
Date du début: 1 oct. 2009, Date de fin: 30 sept. 2015,
RationaleThe inability of pre-clinical studies to predict clinical efficacy is a major bottleneck in drug development. In severe asthma this bottleneck results from: a lack of useful and validated biomarkers, underperforming pre-clinical models, inadequate and incomplete sub-phenotyping, and insufficient disease understanding.HypothesisThe use of biomarker profiles comprised of various types of hi ...
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42
Participants partenaires
TERMINÉ
International network for capacity building for the control of emerging viral vector borne zoonotic diseases (ARBO-ZOONET)
Date du début: 1 mai 2008, Date de fin: 31 oct. 2012,
...ing and harmonizing disease detection and control tools; 4) disseminating knowledge and training staff of relevant third countries; 5) interlinking different scientific disciplines which look at the problem from differrent angles. A coordinated research programme including key laboratories in Europe and neighbouring countries can address scientific questions of joint interest enabling the developm ...
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