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20 projets européens trouvés

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 TERMINÉ 

Biological Foundation for the Safety Classification of Engineered Nanomaterials (ENM): Systems Biology Approaches to Understand Interactions of ENM with Living Organisms and the Environment (NANOSOLUTIONS)

Date du début: 1 avr. 2013, Date de fin: 31 mars 2017,

The main objective of this research proposal is to identify and elaborate those characteristics of ENM that determine their biological hazard potential. This potential includes the ability of ENM to induce damage at the cellular, tissue, or organism levels by interacting with cellular structures leading to impairment of key cellular functions. These adverse effects may be mediated by ENM-induced a ...
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 40

 TERMINÉ 

SUSTAINABLE NANOTECHNOLOGIES (SUN)

Date du début: 1 oct. 2013, Date de fin: 31 mars 2017,

SUN (Sustainable Nanotechnologies) is the first project addressing the entire lifecycle of nanotechnologies to ensure holistic nanosafety evaluation and incorporate the results into tools and guidelines for sustainable manufacturing, easily accessible by industries, regulators and other stakeholders. The project will incorporate scientific findings from over 30 European projects, national and inte ...
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 38

 TERMINÉ 

A common European approach to the regulatory testing of nanomaterials (NANOREG)

Date du début: 1 mars 2013, Date de fin: 28 févr. 2017,

The innovative and economic potential of Manufactured Nano Materials (MNMs) is threatened by a limited understanding of the related EHS issues. While toxicity data is continuously becoming available, the relevance to regulators is often unclear or unproven. The shrinking time to market of new MNM drives the need for urgent action by regulators. NANoREG is the first FP7 project to deliver the answe ...
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 73

 TERMINÉ 

eNanoMapper - A Database and Ontology Framework for Nanomaterials Design and Safety Assessment (ENANOMAPPER)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2017,

eNanoMapper will develop a data management and analysis infrastructure together with ontologies supporting the safety assessment activities of the European Nanomaterials research and development community. The project will address the requirements of safety assessment of nanomaterials by providing databases, analysis tools and ontologies for risk assessment and linking them with existing resources ...
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 11

 TERMINÉ 

European Asthma Research and Innovation Partnership (EARIP)

Date du début: 1 sept. 2013, Date de fin: 31 août 2016,

Europe has 30 million people with asthma, whose treatment costs about €20 bn annually. Productivity lost through poor asthma control in Europe is estimated to be €9.8 bn per year. By 2020 approximately 120,000 people in Europe will die from asthma attacks, and 4 million hospitalisations will be needed for the most severely affected.The Objectives of EARIP (European Asthma Research and Innovation P ...
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 14

 TERMINÉ 

Airway Disease PRedicting Outcomes through Patient Specific Computational Modelling (AirPROM)

Date du début: 1 mars 2011, Date de fin: 30 juin 2016,

The airways diseases asthma and chronic obstructive pulmonary disease affect over 400 million people world-wide and cause considerable morbidity and mortality. Airways disease costs the European Union in excess of €56 billion per annum. Current therapies are inadequate and we do not have sufficient tools to predict disease progression or response to current or future therapies. Our consortium, Air ...
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 40

 TERMINÉ 

Graphene-Based Revolutions in ICT And Beyond (GRAPHENE)

Date du début: 1 oct. 2013, Date de fin: 31 mars 2016,

This Flagship aims to take graphene and related layered materials from a state of raw potential to a point where they can revolutionize multiple industries – from flexible, wearable and transparent electronics, to new energy applications and novel functional composites.Our main scientific and technological objectives in the different tiers of the value chain are to develop material technologies fo ...
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 154

 TERMINÉ 

ToxBank – Supporting Integrated Data Analysis and Servicing of Alternative Testing Methods in Toxicology (TOXBANK)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2015,

ToxBank establishes a dedicated web-based warehouse for toxicity data management and modelling, a ‘gold standards’ compound database and repository of selected test compounds, and a reference resource for cells, cell lines and tissues of relevance for in vitro systemic toxicity research carried out across the FP7 HEALTH.2010.4.2.9 Alternative Testing Strategies SEURAT program. The project develops ...
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 10

 TERMINÉ 

Managing Risks of Nanoparticles (MARINA)

Date du début: 1 nov. 2011, Date de fin: 31 oct. 2015,

While there are standard procedures for product life cycle analysis, exposure, hazard, and risk assessment for traditional chemicals, is not yet clear how these procedures need to be modified to address all the novel properties of nanomaterials. There is a need to develop specific reference methods for all the main steps in managing the potential risk of ENM. The aim of MARINA is to develop such ...
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 54

 TERMINÉ 

Unbiased Biomarkers for the Prediction of Respiratory Disease Outcomes (U-BIOPRED)

Date du début: 1 oct. 2009, Date de fin: 30 sept. 2015,

RationaleThe inability of pre-clinical studies to predict clinical efficacy is a major bottleneck in drug development. In severe asthma this bottleneck results from: a lack of useful and validated biomarkers, underperforming pre-clinical models, inadequate and incomplete sub-phenotyping, and insufficient disease understanding.HypothesisThe use of biomarker profiles comprised of various types of hi ...
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 42

 TERMINÉ 

Design and Manufacturing of Catalytic Membrane Reactors by developing new nano-architectured catalytic and selective membrane materials (DEMCAMER)

Date du début: 1 juil. 2011, Date de fin: 30 juin 2015,

The DEMCAMER project proposes an answer to the paradigm met by the European Chemical Industry: increase the production rate while keeping the same products quality and reducing both production costs and environmental impacts. Through the implementation of a novel process intensification approach consisting on the combination of reaction and separation in a “Catalytic Membrane Reactor” single unit. ...
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 20

 TERMINÉ 

Transport related Air Pollution and Health impacts – Integrated Methodologies for Assessing Particulate Matter (TRANSPHORM)

Date du début: 1 janv. 2010, Date de fin: 30 juin 2014,

TRANSPHORM brings together leading air quality and health researchers and users to improve the knowledge of transport related airborne particulate matter (PM) and its impact on human health and to develop and implement assessment tools for scales ranging from city to Europe. Over four years, TRANSPHORM will aim to develop and implement an integrated methodology to assess the health impacts of PM a ...
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 21

 TERMINÉ 

Robust Advanced Materials for metal Supported SOFC (RAMSES)

Date du début: 1 janv. 2011, Date de fin: 31 mai 2014,

"The RAMSES project aims at developing an innovative high performance, robust, durable and cost-effective Solid Oxide Fuel Cell based on the Metal Supported Cell concept i.e. the deposition of thin ceramic electrodes and electrolyte on a porous metallic substrate. Both planar and tubular cells will be developed. By considering advanced materials tailored for this cell design, such cells will be ab ...
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 10

 TERMINÉ 

Transcriptional mutagenesis in mammalian cell systems: p53 signaling as a probe of cellular effects (TMP53COMPMIX)

Date du début: 1 mai 2010, Date de fin: 30 avr. 2014,

"The process of misincorporation of incorrect bases into the nascent RNA as a result of DNA-lesion bypass by RNA polymerases during transcription is referred to as transcriptional mutagenesis (TM). Although this has been shown to alter the subsequent proteins function, the relative importance of TM in human health is virtually untouched. I propose to study the cellular effects and biological signi ...
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 1

 TERMINÉ 

"Augmented Usage of Track by Optimisation of Maintenance, Allocation and Inspection of railway Networks" (AUTOMAIN)

Date du début: 1 févr. 2011, Date de fin: 31 janv. 2014,

"Rail traffic has increased much in the last decade. This development and the need for model shift from road to rail to decrease CO2 emission, creates a challenge for the railway industry to improve capacity in the network while the need of capacity for maintenance also increases.The challenge of the project is to do more effective inspection and maintenance in less time.Therefore the project focu ...
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 18

 TERMINÉ 

European coordination action on human biomonitoring (COPHES)

Date du début: 1 déc. 2009, Date de fin: 30 nov. 2012,

This proposal has been elaborated by a consortium of 35 partners coming from 27 European countries and including scientists, government institutions and authorities, NGOs and industry. The main goal is to develop a coherent approach to HBM in Europe as requested by ACTION 3 of the EU Environment and Health Action Plan through coordination of ongoing and planned HBM activities. The project will exp ...
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 40

 TERMINÉ 

European Study of Cohorts for Air Pollution Effects (ESCAPE)

Date du début: 1 juin 2008, Date de fin: 30 nov. 2012,

"European policy making is hampered by considerable uncertainty about the magnitude and nature of the impacts of long term exposure to air pollution on human health. ESCAPE is a collaboration of more than 30 European cohort studies including some 900,000 subjects. It is aimed at quantifying health impacts of air pollution and at reducing uncertainty. ESCAPE will also test new hypotheses on specifi ...
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 26

 TERMINÉ 

"Apoptosis systems biology applied to cancer and AIDS. An integrated approach of experimental biology, data mining, mathematical modelling, biostatistics, systems engineering and molecular medicine" (APO-SYS)

Date du début: 1 févr. 2008, Date de fin: 31 janv. 2012,

"A Europe-wide consortium of experimental biologists, biomathematicians, biostatisticians, computer scientists and clinical scientists will team up to approach cell death pathways in health and disease, placing particular emphasis on cancer and AIDS. The consortium will create a unique database integrating existing and accumulating knowledge on lethal signal transduction pathways leading to apopto ...
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 24

 TERMINÉ 

European Network on Noise And Health (ENNAH)

Date du début: 1 sept. 2009, Date de fin: 31 janv. 2012,

"This proposal puts forward plans to establish a research network of experts on noise and health in Europe. This network will establish future research directions and policy needs in Europe. The network will review the existing literature on environmental noise exposure and health focussing on the consolidation of existing state of the art knowledge and the identification of gaps in the evidence a ...
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 37

 TERMINÉ 

Comprehensive assessment of hazardous effects of engineered nanomaterials on the immune system (NANOMMUNE)

Date du début: 1 sept. 2008, Date de fin: 31 août 2011,

Engineered nanomaterials (ENs) present tremendous opportunities for industrial growth and development, and hold great promise for the enrichment of the lives of citizens, in medicine, electronics, and numerous other areas. However, there are considerable gaps in our knowledge concerning the potential hazardous effects of ENs on human health and the environment. Our EU-US partnership is committed t ...
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 10