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27 projets européens trouvés

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 TERMINÉ 

Translating neuroimaging findings from research into clinical practice (PSYSCAN)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2020,

Abstract 9Neuroimaging (NI) has enormous potential to improve the clinical care of patients with psychiatric disorders, but has yet to deliver. The PSYSCAN project will address this issue directly by developing a NI-based tool that will help clinicians resolve key clinical issues in the management of patients with psychotic disorders. Clinicians will use the tool to assess patients with a standard ...
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 24

 TERMINÉ 

"Family life courses, intergenerational exchanges and later life health" (FAMHEALTH)

Date du début: 1 juil. 2013, Date de fin: 30 juin 2018,

"The overall aim of this research programme is to uncover how family life courses influence health and well-being in later adulthood, whether family related strengths or disadvantages relevant to health offset or compound socio-economic sources of disadvantage, and the extent to which these associations are influenced by societal factors. An important element will be to consider the role of interg ...
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 4

 TERMINÉ 

European Medical Information Framework (EMIF)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,

In response to the need to tackle increasingly complex medical research questions, a growing amount of human health data is being collected, either in routine Electronic Healthcare Record (EHR) databases, through research-driven cohort studies, in biobanks or related efforts. However, data sources are typically fragmented and contain information gaps which prevent their full exploitation. EMIF aim ...
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 64

 TERMINÉ 

QUantitative Imaging in Cancer: CONnecting CEllular Processes with Therapy (QUIC-CONCEPT)

Date du début: 1 sept. 2011, Date de fin: 31 déc. 2017,

The QuIC-ConCePT consortium has 2 objectives: 1.(90% of resource, WP2-5) to qualify 3 specific imaging biomarkers (IBs) of tumour cell proliferation, apoptosis, and necrosis, to allow drug developers to demonstrate reliably modulation of these pathologic processes in tumours in patients in realistic trials. Our vision for January 2016 is that drug developers can incorporate these IBs for decision- ...
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 26

 TERMINÉ 

Preparing for Extreme And Rare events in coastaL regions (PEARL)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2017,

"Coastal floods are one of the most dangerous and harmful natural hazards affecting urban areas adjacent to shorelines. Rapid urbanisation combined with climate change and poor governance means a significant increase in the risk of local surface flooding coinciding with high water levels in rivers and high tide or storm surges from the sea, posing a greater risk of devastation to coastal communiti ...
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 26

 TERMINÉ 

"High resolution monitoring, real time visualization and reliable modeling of highly controlled, intermediate and up-scalable size pilot injection tests of underground storage of CO2" (TRUST)

Date du début: 1 nov. 2012, Date de fin: 31 oct. 2017,

"TRUST aims at conducting CO2 injection experiments at scales large enough so that the output can be extrapolated at industrial scales. It relies on four sites: the heavily instrumented sites of Heletz (Israel, main site) and Hontomin (Spain), access Miranga (Brazil) and the emerging site in the Baltic Sea region. The objectives are to: carry out CO2 injection with different strategies, displaying ...
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 18

 TERMINÉ 

Single-Port Insulin Infusion for Improved Diabetes Management (SPIDIMAN)

Date du début: 1 nov. 2012, Date de fin: 31 oct. 2017,

Existing therapeutic devices for diabetic patients suffer from bulky size, inaccurate measurements and the difficulties of handling two body interfaces. Suboptimal control of blood glucose levels in type 1 or type 2 diabetes mellitus patients results in periods of hypo- and hyperglycaemia leading to severe and life-threatening complications. Exploiting a novel glucose sensor technology, SPIDIMAN a ...
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 9

 TERMINÉ 

Long-term effects of early nutrition on later health (EARLYNUTRITION)

Date du début: 1 févr. 2012, Date de fin: 31 oct. 2017,

Nutrition during early development has an important impact on later health, particularly through greater obesity risk, as demonstrated by FP6 EARNEST. EarlyNutrition explores the current key hypotheses on likely causes and pathways to prevention of early life origins of obesity (specifically adiposity) and associated disorders. We bring extraordinary expertise and study populations of 470,000 indi ...
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 40

 TERMINÉ 

Translational Adolescent and Childhood Therapeutic Interventions in Compulsive Syndromes (TACTICS)

Date du début: 1 janv. 2012, Date de fin: 30 juin 2017,

Compulsivity is characterized by a repetitive, irresistible urge to perform a behavior, the experience of loss of voluntary control over this intense urge, the diminished ability to delay or inhibit thoughts or behaviors, and the tendency to perform repetitive acts in a habitual or stereotyped manner. Compulsivity is a cross-disorder trait underlying phenotypically distinct psychiatric disorders t ...
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 13

 TERMINÉ 

European Autism Interventions - A Multicentre Study for Developing New Medications (EU-AIMS)

Date du début: 1 avr. 2012, Date de fin: 31 mars 2017,

Despite dramatic advances in molecular and imaging technologies, there are currently no effective pharmacological treatments for the core symptoms of autism spectrum disorder (ASD). Major obstructions to this include a lack of aetiologically-driven or pathophysiologically-accurate animal models; an absence of tests that indicate efficacy; and reliance of clinical trials on DSM/ICD10 categories wh ...
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 29

 TERMINÉ 

Cardiac myosin light chain kinase function in human pluripotent stem cell derived cardiomyocytes (hES-Cardio)

Date du début: 14 sept. 2012, Date de fin: 31 déc. 2016,

The main hurdle to the effective use of stem cell derived cardiomyocytes (hESC-CMs and hIPSC-CMs) in drug toxicology screening and transplantation therapy is their embryonic nature. It is recognised that hESC-CM and hIPSC-CM are immature and undergo limited maturation in the laboratory. This creates problems as the cells may not display appropriate responses to target drugs in toxicology screening ...
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 2

 TERMINÉ 

3to4: Converting C3 to C4 photosynthesis for sustainable agriculture (3TO4)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2016,

Most plants use the C3 pathway of photosynthesis that is compromised by gross inefficiencies in CO2 fixation. However, some plants use a super-charged photosynthetic mechanism called C4 photosynthesis. The C4 pathway is used by the most productive vegetation and crops on Earth. In addition to faster photosynthesis, C4 plants demand less water and less nitrogen. Overall, our aim is to introduce the ...
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 20

 TERMINÉ 

Natural Killer Cell-Based Anti-Cancer Immunotherapies: Research training in molecular medicine and biotechnology business (NATURIMMUN)

Date du début: 1 oct. 2012, Date de fin: 30 sept. 2016,

"In the research part we will deal with the basic principles of the innate immune defense used to control tumors and viral infections with a focus on NK and NK/T cells, including analysis of NK receptor genomics/epigenetics, gene polymorphisms/disease linkage, differentiation of hitherto unrecognized NK cell subpopulations and novel ligands for NK receptors exposed by tumor and/or virally infected ...
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 12

 TERMINÉ 

User-Centric Networking (UCN)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2016,

Description The UCN project introduces User Centric Networking, which is a communication new paradigm leveraging user information at large, to deliver novel user-centric connected media services.The explosion of information available online and the ubiquity of connected media devices are rendering existing content recommendation and conte ...
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 11

 TERMINÉ 

Multi-Sensor-Platform for Smart Building Management (MSP)

Date du début: 1 sept. 2013, Date de fin: 31 août 2016,

The concept of the MSP project is based on a multi-project wafer approach that enables the development of highly innovative components and sensors based on Key Enabling Technologies (KETs). The central objective of the MSP-project is the development of a technology and manufacturing platform for the 3D-integration of sophisticated components and sensors with CMOS technology being the sound foundat ...
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 17

 TERMINÉ 

Advanced fuelS for Generation IV reActors: Reprocessing and Dissolution (ASGARD)

Date du début: 1 janv. 2012, Date de fin: 30 juin 2016,

Nuclear power issues have been attracting research interest for decades even since the actual use of power reactors using oxide fuels was considered a mature science. It has mainly been due to one of the great drawbacks of nuclear power, the waste handling. Presently, there is a renaissance in nuclear power research focused on a new generation of reactor concepts utilising more of the inherent ene ...
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 16

 TERMINÉ 

Accelerated Metallurgy - the accelerated discovery of alloy formulations using combinatorial principles (AccMet)

Date du début: 15 juin 2011, Date de fin: 14 juin 2016,

"The core concept of Accelerated Metallurgy is to deliver an integrated pilot-scale facility for the combinatorial synthesis and testing of many thousands of unexplored alloy formulations. This facility would be the first of its kind in the world and would represent a significant advance for metallurgy. The novel technology that enables this HTT facility is based on automated, direct laser deposit ...
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 34

 TERMINÉ 

Graphene-Based Revolutions in ICT And Beyond (GRAPHENE)

Date du début: 1 oct. 2013, Date de fin: 31 mars 2016,

This Flagship aims to take graphene and related layered materials from a state of raw potential to a point where they can revolutionize multiple industries – from flexible, wearable and transparent electronics, to new energy applications and novel functional composites.Our main scientific and technological objectives in the different tiers of the value chain are to develop material technologies fo ...
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 154

 TERMINÉ 

3D acquisition, processing and presentation of prehistoric European rock-art (3D-PITOTI)

Date du début: 1 mars 2013, Date de fin: 29 févr. 2016,

There is ancient rock-art in most European countries and it is more common than cave art, with pictures and geometric shapes cut into rather than painted onto rock. This art exists in open-air surfaces exposed to the weather rather than inside caves. This wealth of Europe's cultural heritage is inaccessible, difficult to study but provides profound stories from our ancient past. Valcamonica, in th ...
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 7

 TERMINÉ 

Novel biomimetic strategy for bone regeneration (INNOVABONE)

Date du début: 1 nov. 2011, Date de fin: 31 oct. 2015,

The importance of developing novel approaches for bone repair is underscored by the heavy burden on health care costs and patient suffering caused by traumatic, osteoporotic and osteolytic metastatic bone lesions. To address these health challenges, we will develop optimally performing bioinspired biomaterials mimicking the natural physiological processes underlying bone repair. Our overall approa ...
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 14

 TERMINÉ 

Novel Methods leading to New Medications in Depression and Schizophrenia (NEWMEDS)

Date du début: 1 sept. 2009, Date de fin: 28 févr. 2015,

Despite dramatic advances in molecular and imaging technologies and nearly 1 5,000 articles on schizophrenia and depression (S&D) there are few novel treatments. We think this is because of three major “bottle-necks”: a lack of etiologically-driven or pathophysiologically-accurate animal models; a lack of tests that provide indication of efficacy in healthy volunteers; and the reliance of clinical ...
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 20

 TERMINÉ 

Cluster of Research Infrastructures for Synergies in Physics (CRISP)

Date du début: 1 oct. 2011, Date de fin: 30 sept. 2014,

The objective of the eleven participating Research Infrastructures (RIs) is to build up collaborations and to create long-term synergies to facilitate their implementation and enhance their efficiency and attractiveness. The CRISP proposal focuses on four R&D tasks that are of utmost importance for these RIs: (i) Accelerators, (ii) Instruments & Experiments, (iii) Detectors & Data Acquisition, and ...
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 17

 TERMINÉ 

Innovative Synthesis in Continuous-Flow Processes for Sustainable Chemical Production (SYNFLOW)

Date du début: 1 sept. 2010, Date de fin: 31 août 2014,

The SYNFLOW vision is the paradigm shift from batch-wise large volume processes in pharmaceuticals, fine chemicals and intermediates production comprising many separate unit operations towards highly integrated but yet flexible catalytic continuous flow processing. For this purpose, SYNFLOW develops a unique integrative approach combining molecular understanding of synthesis and catalysis with eng ...
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 23

 TERMINÉ 

Innovation for Digital Fabrication (Diginova)

Date du début: 1 mars 2012, Date de fin: 28 févr. 2014,

Most products are produced by means of the established mass production infrastructure. Traditionally, this involves large stocks, high manual labor, large capital investments, high energy use, long distance transportation. Although many advanced new materials have unique functional properties that hold a great promise for innovation, they often need to meet the criteria and characteristics of this ...
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 22

 TERMINÉ 

Light-based functional in vivo monitoring of diseases related enzymes (LIVIMODE)

Date du début: 1 nov. 2009, Date de fin: 30 avr. 2013,

"LIVIMODE aims to develop specific tools for non invasive in vivo imaging of disease related molecular events. Such tools are of high relevance for disease detection, staging, developing animal models of human disease, and evaluating novel therapies. We propose to use optical imaging, which is optimally suited for this task as it provides excellent sensitivity and allows visualizing molecular even ...
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 13

 TERMINÉ 

Personalised and intergrated cardiac care: \nPatient-specific Cardiovascular Modelling and Simulation for In Silico Disease Understanding and Management (euHeart)

Date du début: 1 juin 2008, Date de fin: 30 nov. 2012,

Cardiovascular disease (CVD) has a significant impact on the European society in terms of mortality, morbidity and allied healthcare costs. The opportunity of multi-scale modelling spanning, sub-cellular level up to whole heart is to improve CVD outcomes by providing a consistent, biophysically-based framework for the integration of the huge amount of fragmented and inhomogeneous data currently av ...
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 21

 TERMINÉ 

Guardian Angels for a Smarter Life (Guardian Angels)

Date du début: 1 mai 2011, Date de fin: 30 avr. 2012,

Guardian Angels (GA) are future zero-power, intelligent, autonomous systems-of-systems featuring sensing, computation, and communication beyond human aptitudes. GA will assist humans from their infancy to old age in complex life situations and environments. Zero-power reflects system-of-systems ability to scavenge energy in dynamic environments by disruptive harvesting techniques. The project prep ...
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 34