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 EN COURS 
The problem: finding the right patient for the right treatmentDespite a large and growing disease burden in osteoarthritis (OA), many pharmaceutical companies have de-emphasized or even abandoned OA drug development due to perceived hurdles. Crucial in this is the lack of appropriate outcome measures that can robustly identify patient benefit from a specific therapy. The lack of specific and sensi ...
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 25

 TERMINÉ 

Gas and Dust from the Stars to the Laboratory: Exploring the NanoCosmos (NANOCOSMOS)

Date du début: 1 août 2014, Date de fin: 31 juil. 2020,

Evolved stars are the factories of interstellar dust. This dust is injected into the interstellar medium and plays a key role in the evolution of astronomical objects from galaxies to the embryos of planets. However, the processes involved in dust formation and evolution are still a mystery. The increased angular resolution of new generation telescopes, will provide for the first time a detailed v ...
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 5

 TERMINÉ 

Cracking the emotional code of music (CREAM)

Date du début: 1 oct. 2014, Date de fin: 30 sept. 2019,

"This project aims to ""crack"" the emotional code of music, i.e. to provide, for the first time, a precise characterization of what type of music signal is able to activate one emotion or another. Research into this problem so far has been mainly correlating indistinct emotional reactions to uncontrolled musical stimuli, with much technical sophistication but to little avail. Project CREAM builds ...
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 1

 TERMINÉ 
"Many current theories implicate brain oscillations in perception, attention, consciousness or memory. This, however, has one critical implication that is often overlooked in cognitive sciences: if a perceptual function relies on an oscillatory basis, then it should operate periodically, as a sequence of successive episodes or 'snapshots', with more or less favourable moments recurring at a well-d ...
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 1

 TERMINÉ 
The cerebral microvascular system is essential to a large variety of physiological processes in the brain, including blood delivery and blood flow regulation as a function of neuronal activity (neuro-vascular coupling). It plays a major role in the associated mechanisms leading to disease (stroke, neurodegenerative diseases, …). In the last decade, cutting edge technologies, including two-photon s ...
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 3

 TERMINÉ 

Maintenance of epigenome integrity in response to DNA damage (EpIn)

Date du début: 1 mars 2014, Date de fin: 28 févr. 2019,

Protection of genome integrity is crucial for maintaining cell identity and viability. However, the organisation of DNA with histone proteins into chromatin in eukaryotic cell nuclei poses structural constraints to the detection and repair of DNA lesions. Dynamic and tightly controlled changes in chromatin organisation are thus critical for an efficient response to DNA damage, while at the same ti ...
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 1

 TERMINÉ 
"How robust phenotypes evolve despite developmental noise remains unclear. Individuals from natural populations usually display more stable phenotypes than laboratory mutants and hybrids. This suggests that there are genetic mechanisms that stabilize phenotypes and that these differ between isolated populations. We want to address here an unexplored yet fundamental question in biology: how does a ...
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 1

 TERMINÉ 

Computational Foundations of Anthropomorphic Action (Actanthrope)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2018,

Actanthrope intends to promote a neuro-robotics perspective to explore original models of anthropomorphic action. The project targets contributions to humanoid robot autonomy (for rescue and service robotics), to advanced human body simulation (for applications in ergonomics), and to a new theory of embodied intelligence (by promoting a motion-based semiotics of the human action).Actions take plac ...
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 1

 TERMINÉ 

Dynamics-aerosol-chemistry-cloud interactions in West Africa (DACCIWA)

Date du début: 1 déc. 2013, Date de fin: 30 nov. 2018,

"Massive economic and population growth and urbanisation are expected to lead to a tripling of anthropogenic emissions in southern West Africa (SWA) between 2000 and 2030, the impacts of which on human health, ecosystems, food security and the regional climate are largely unknown. An assessment of these impacts is complicated by (a) a superposition with effects of global climate change, (b) the st ...
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 17

 TERMINÉ 

Memory Mechanisms in Man and Machine (M4)

Date du début: 1 mai 2013, Date de fin: 30 avr. 2018,

"The project aims to validate a set of 10 provocative claims. 1) Humans can recognize visual and auditory stimuli that they have not experienced for decades. 2) Recognition is possible without ever reactivating the memory trace in the intervening period. 3) During memorization, sensory memory strength increases roughly linearly with the number of exposures. 4) A few tens of presentations can be en ...
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 1

 TERMINÉ 

Quantum Communication and Cryptography (QCC)

Date du début: 1 mai 2013, Date de fin: 30 avr. 2018,

"Quantum Information Processing has the potential to revolutionize the future of information technologies. My long-term vision is a network of quantum and classical devices, where individual agents have the ability to communicate efficiently in a variety of ways with trusted and untrusted parties and securely delegate computational tasks to a number of untrusted large-scale quantum computing serve ...
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 1

 TERMINÉ 

ISOTOPIC TOOLS AS NOVEL SENSORS OF EARTH SURFACE RESOURCES (IsoNose)

Date du début: 1 mars 2014, Date de fin: 28 févr. 2018,

Soil, water, and precious metals are major natural resources present at the Earth´s terrestrial surface and their efficient management is essential for future sustainable development. Their availability is regulated by massive biogeochemical transformations that take place as the chemical elements move from rock to soil, into plants, through ground water, into river water, and into ore deposits. T ...
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 8

 TERMINÉ 
"The main goal of the ""World Seastems"" project is to map for the first time the changing spatial pattern of the world economy from a maritime perspective across 300 years. It will exploit untapped vessel movement data available since 1734, date of the first Lloyd's List register. There are three main goals of the project. First, it aims at mapping for the first time the spatial distribution of ...
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 1

 TERMINÉ 
Carrier spin states in semiconductor nano-structures can be manipulated with fast optical pulses via the optical selection rules. The electron and hole spins in quantum dots interact strongly with the nuclear spins in the host material via the hyperfine interaction. This allows a new, versatile approach to nuclear spintronics, namely applying fast optical initialisation to carrier states and subse ...
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 1

 TERMINÉ 

European Facility for Airborne Research in Environmental and Geo-sciences (EUFAR2)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,

EUFAR aims at providing researchers with Open Access to the airborne facilities the most suited to their needs. EUFAR thus allocates Transnational Access to 21 installations, develops a culture of co-operation between scientists and operators, and organizes training courses to attract young scientists to airborne research. To improve the quality of the service, EUFAR supports the experts on airbor ...
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 24

 TERMINÉ 
"INTECOCIS is a project on energy production by combustion built by IMFT (experiments, theory and instabilities) and CERFACS (numerical simulation). Combustion produces 90 percent of the earth energy and will remain our first energy source for a long time. Optimizing combustors is a key issue to burn fossil and renewable fuels more efficiently but also to replace wind or solar energy production on ...
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 2

 TERMINÉ 

Ice, Climate, and Economics - Arctic Research on Change (ICE-ARC)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2017,

The ICE-ARC project aims to understand and quantify the multiple stresses involved in the change in the Arctic marine environment. Particular focus is on the rapid retreat and collapse of the Arctic sea ice cover and to assess the climatic (ice, ocean, atmosphere and ecosystem), economic and social impacts of these stresses on regional and global scales.It is not possible to look at one aspect of ...
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 26

 TERMINÉ 
Clouds are a very important, yet not well understood feedback factor in climate change and they contribute to the effective radiative forcing (ERF) from aerosol-cloud interactions (ACI). The uncertainty in ERFaci is larger than for any other forcing agent. Also, feedbacks between the terrestrial and marine biosphere and the atmosphere involving ACI are thought to play an important role in regulati ...
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 22

 TERMINÉ 

Philosophy of Canonical Quantum Gravity (PhiloQuantumGravity)

Date du début: 1 nov. 2011, Date de fin: 31 oct. 2017,

This research proposal addresses from a philosophical perspective the greatest unsolved problem of theoretical physics, namely the formulation of a quantum theory of gravity. Quantum mechanics and general relativity are the two main revolutions of 20th century physics. These theories have radically modified our conceptions about time, space, motion, matter and causality. However, the formulation o ...
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 1

 TERMINÉ 

SenseOCEAN: Marine sensors for the 21st Century (SenseOcean)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

SenseOCEAN brings together the leading sensor developers from academia and industry across Europe to enable a quantum leap in worldwide in situ ocean biogeochemical sensor technology. It will produce fundamental innovations in analytical sciences fusing together new techniques for microfabrication, system integration, self calibration and cost-effective mass production. It will deliver a new prod ...
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 12

 TERMINÉ 

Planar Atomic and Molecular Scale devices (PAMS)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

The PAMS project will explore all scientific and technological aspects of the fabrication of planar atomic and sub-molecular scale electronic devices on surfaces of Si:H, Ge:H, AlN, CaCO3 (calcite) and CaF2 with atomic scale precision and reproducibility. The sub-nanoscale devices will be made by combining ultra-precise Scanning Tunnelling Microscopy (STM) and non-contact-Atomic Force Microscopy ( ...
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 8

 TERMINÉ 

Factory-in-a-day (FACTORY-IN-A-DAY)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

"Factory-in-a-Day aims at improving the competitiveness of European manufacturing SMEs by removing the primary obstacle for robot automation; installation time and installation cost. The high costs result in payback periods, making the investment in robotized automation economically unattractive. Factory-in-a-Day will reduce the installation time (and the related cost) from months to one single d ...
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 18

 TERMINÉ 

Low-valent silicon complexes:Transition metal-like catalysts (NEWSILICON)

Date du début: 1 sept. 2012, Date de fin: 31 août 2017,

"This project principally concerns the use of silicon (the second most abundant element in the Earth’s crust) as catalyst instead of transition metals. Although the importance of its abundance is well recognized in material chemistry, as it can be seen by the vast world production of silicon based materials (polymers, rubber, semiconductors), real success in chemistry with such a vision has never ...
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 1

 TERMINÉ 

Geologic Carbon Storage (CO2-REACT)

Date du début: 1 mars 2013, Date de fin: 28 févr. 2017,

The CO2-REACT ITN has been created to address twin objectives: (1) to provide urgently needed training in CO2 storage preparing candidates for critical roles in the coming years and (2) to significantly advance our understanding of the fate and consequences of CO2 injection into the subsurface during carbon storage efforts. The CO2-REACT ITN addresses these objectives through a balanced combinat ...
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 11

 TERMINÉ 
Humans carry out actions either in response to environmental demands, or independently of external input in order to achieve their goals. The first type of action may be referred to as stimulus-based or reactive, the latter kind may be referred to as intention-based or voluntary. Voluntary actions are an important component of our interaction with the environment and our social lives. Yet, researc ...
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 1

 TERMINÉ 

Online Network TraffIc Characterization (ONTIC)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2017,

Accurate identification and categorization of network traffic is a crucial task in many network management and engineering activities, such as QoS evaluation, capacity planning and attack detection. Terabytes of data may be transferred through the core network of a typical ISP every day, and an exponential growth in traffic is expected in the short-term, with more than 50 billions of Internet-conn ...
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 7

 TERMINÉ 
"We propose to establish a training network for the development of intelligent devices and tools for cutting-edge applications in Astrophysics, High Energy Physics, Medical Physics and Telecommunications. The network aims to develop new technologies and algorithms, with a common theme of placing intelligence into data-acquisition, processing and transmission technologies very close to the informat ...
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 11

 TERMINÉ 

A European Training Network for Sustainable Phosphorus Chemistry (SusPhos)

Date du début: 1 févr. 2013, Date de fin: 31 janv. 2017,

The SusPhos training network will bring about a paradigm shift in the teaching of sustainable phosphorus chemistry, in the training of multidisciplinary-competent scientists, and in the public’s view on chemistry to preserve the essential element phosphorus from depletion. SusPhos represents the first systematic investigation of the eco-friendly production, smart use, recycling and commercial expl ...
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 14

 TERMINÉ 

EU-Belarus-Russia Network in Nanomaterials-Driven Anti-Cancer Gene Therapy (NANOGENE)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

"Dendrimers are a new class of nanomaterials. They are monodisperse, stable, and are characterized by relatively low viscosity at high molecular mass and numerous end groups that can be ionized, which means that they can efficiently bind a large amount of genetic material and deliver it to ill organs and tissues (gene therapy). The partners of project from EU countries organized European research ...
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 5

 TERMINÉ 

The development of in silico process models for roll compaction (IPROCOM)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

"Particulate materials, e.g. pharmaceutical formulations, precious metal, fine chemical, metal & ceramic powders, have been compacted to produce a wide range of particulate products in a number of industrial sectors. The diversity of particulate materials and the complexity of manufacturing processes make it a challenging task in product development and process design for particulate product manuf ...
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 10

 TERMINÉ 

TWO!EARS

Date du début: 1 déc. 2013, Date de fin: 30 nov. 2016,

TWO!EARS replaces current thinking about auditory modelling by a systemic approach in which human listeners are regarded as multi-modal agents that develop their concept of the world by exploratory interaction. The goal of the project is to develop an intelligent, active computational model of auditory perception and experience in a multi-modal context. Our novel approach is based on a structural ...
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 11

 TERMINÉ 

Mathematical Sciences in the Ancient World (SAW)

Date du début: 1 nov. 2011, Date de fin: 31 oct. 2016,

"The SAW project is devoted to mathematical sources that have come down to us from the ancient world and, more specifically, though not exclusively, to the sources produced in Mesopotamia, China, and the Indian subcontinent. The scope of SAW is inspired by an analysis of the state of the art in the history of mathematics of the ancient world. The project also derives from an analysis of the presen ...
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 1

 TERMINÉ 

Imperial Government and Authority in Medieval Western Islam (IGAMWI)

Date du début: 1 oct. 2010, Date de fin: 30 sept. 2016,

My project is to write a new history of the Almohad Empire (1130-1269). This local dynasty of Berber origins ruled simultaneously over South and North of the Western Mediterranean. For the first time in history, the whole Maghreb was united under an indigenous authority. This unique historical period witnessed very important process, the political and religious separation from the East through ...
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 1

 TERMINÉ 
The goal of the KoroiBot project is to enhance the ability of humanoid robots to walk in a dynamic and versatile fashion in the way humans do. Research and innovation work in KoroiBot will mainly target novel motion control methods for existing hardware, but it will also derive optimized design principles for next generation robots.By doing so, KoroiBot addresses the ambitious goals set for the hu ...
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 7

 TERMINÉ 

MATerials for FLEXible ENergy harvesting Devices (Matflexend)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2016,

MATFLEXEND investigates new materials which enable capacitive-mechanical energy harvesters with significantly improved power density and efficiency. Such materials will be durable, solution-processible, flexible, and therefore enable mass-production techniques including printing.The “REWOD” principle (Reverse-Electrowetting-On-Dielectric) will be developed for small-scale energy scavenging, and a ...
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 11

 TERMINÉ 

Constructing Mathematical Knowledge beyond Core Intuitions (MathConstruction)

Date du début: 1 avr. 2011, Date de fin: 31 août 2016,

Humans and other animals possess dedicated systems of core knowledge to represent numeric and geometric information. In the case of number at least, these representations are abstract (independent of the format of the stimuli represented), they are present early in life, and they can be used to compute the outcome of simple arithmetic problems. Such intuitive knowledge is thought to guide the ac ...
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 1

 TERMINÉ 

The Liber glossarum. Edition of a Carolingian ecyclopaedia (LibGloss)

Date du début: 1 févr. 2011, Date de fin: 31 juil. 2016,

The Liber Glossarum is a very large dictionary (about 30000 entries), compiled in Northern France at the end of the VIIIth c., and combining encyclopaedic, theological, medical and grammatical sources. While being the first European alphabetical dictionary, it is still much neglected by modern scholars, principally because there exist only partial editions from the beginning of the XXth c.This pro ...
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 2

 TERMINÉ 

Safety of ACtinide Separation proceSSes (SACSESS)

Date du début: 1 mars 2013, Date de fin: 30 juin 2016,

"Nuclear power plays a key role in limiting EU’s greenhouse gases emissions, and makes an important contribution to improve European Union’s independence, security and diversity of energy supply. However, its social acceptance is closely linked to an enhanced safety in the management of long-lived radioactive waste contributing to resource efficiency and cost-effectiveness of this energy and ensur ...
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 26

 TERMINÉ 
Cities are today the main form of occupation of the Earth’s surface by human societies, and their development, combining design and self-organisation, sets numerous challenges in terms of collective territorial intelligence. On the scale of national and continent-wide territories, or indeed world-wide territories for the largest, cities are interconnected by way of numerous networks, in particular ...
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 1

 TERMINÉ 

Mineral Scale formation: from the atomic to the field scale (MINSC)

Date du début: 1 juin 2012, Date de fin: 31 mai 2016,

The MINSC Initial Training Network (ITN) is comprised of partners from first-rate universities and high-level industrial partners located in the United Kingdom, France, Denmark, Iceland, Germany, Norway, and Italy. The prime aims of this network is to provide research and training opportunities to a new generation of young fellows in fundamental and collaborative research projects related to the n ...
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 9