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15 projets européens trouvés

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 TERMINÉ 

Multisystem Cell Therapy for Improvement of Urinary Continence (MUSIC)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

"Stress Urinary Incontinence (SUI) is a disease affecting over 200 million people worldwide. It represents a condition with a prevalence of 20-50% in women, thereby creating an immense socio-economic burden. The currently available treatment strategies entail various complications and offer only short-term relief to the patients. Tissue engineering using autologous cells offers a feasible alternat ...
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 5

 TERMINÉ 

A multicenter phase IIb study using HLA-unmatched allogeneic placenta-derived stromal cells (PLX-PAD) for the treatment of severe critical limb ischemia accompanied by mechanistic studies (PACE)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

PACE aims to transform the treatment of patients suffering from critical limb ischemia (CLI), a disease with high medical need, because of limited treatment options and poor outcome by applying a novel, off-the-shelf allogeneic placenta-derived stromal cell product (PLX-PAD). Despite improvements in medical care and revascularization, patients with CLI continue to have a high risk of major amputat ...
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 9

 TERMINÉ 

Tools and TECHNOlogies for Breakthrough in hEArt Therapies (TECHNOBEAT)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

Cardiovascular diseases including myocardial infarction (MI), which entails the irreversible loss of heart muscle tissue, constitute a major socio-economic burden in global healthcare. With whole organ transplantation as the only treatment option for end-stage heart failure, MI patients could particularly benefit from advanced cell therapies aimed at the functional reconstitution of damaged hearts ...
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 8

 TERMINÉ 

Labeling of Enalapril from Neonates up to Adolescents (LENA)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2018,

Children are often treated as small adults—not as the special patients they are. Regulations exist to encourage the development of drugs and formulation for children. However, off-patent drugs are often administered to children without appropriate formulations or systematic investigations. Therefore, the paediatric use marketing authorisation (PUMA) has been designed.The EMA Paediatric Working Par ...
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 14

 TERMINÉ 

Prevention and personalized treatments in knee osteoarthritis: an Initial Training Network (KNEEMO)

Date du début: 29 avr. 2014, Date de fin: 28 avr. 2018,

"Knee Osteoarthritis (KOA) is the most common chronic musculoskeletal disorder, currently affecting over 8 million people within the EU, for which currently no cure is available. Adverse biomechanics, affected through some of the major health issues of our time (ageing, obesity, sedentary lifestyle) lie at the heart of the disease.The research theme of the KNEEMO ITN is “towards targeted and tailo ...
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 8

 TERMINÉ 

Early Prevention of Diabetes Complications in people with Hyperglycaemia in Europe (E-PREDICE)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2017,

"Background: A significant proportion of pre-diabetics, show macro and micro vascular complications associated with hyperglycaemia. Although many trials have demonstrated the efficacy of lifestyle and pharmaceutical interventions in diabetes prevention, no trial has evaluated the extent to which mid- and long-term complications can be prevented by early interventions on hyperglycaemia.Aims: To ass ...
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 37

 TERMINÉ 

Polypharmacy in chronic diseases: Reduction of Inappropriate Medication and Adverse drug events in elderly populations by electronic Decision Support (PRIMA-EDS)

Date du début: 1 déc. 2012, Date de fin: 30 nov. 2017,

Background: Treatment of chronic diseases in the elderly with polypharmacy poses a threat to patient outcome and involves extensive costs. Little evidence exists regarding the benefits of polypharmacy, but rising evidence shows its harmful effects. Several approaches to reduce polypharmacy have been proposed, but none have been evaluated using clinically relevant endpoints.Aims: Based on a systema ...
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 6

 TERMINÉ 

Imaging of Neuroinflammation in Neurodegenerative Diseases (INMiND)

Date du début: 1 mars 2012, Date de fin: 28 févr. 2017,

The goal of this proposal (INMiND) is to carry out collaborative research on molecular mechanisms that link neuroinflammation with neurodegeneration in order to identify novel biological targets for activated microglia, which may serve for both diagnostic and therapeutic purposes, and to translate this knowledge into the clinic. The general objectives of INMiND are:(i) to identify novel mechanisms ...
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 32

 TERMINÉ 

"Identification, homing and monitoring of therapeutic cells for regenerative medicine – Identify, Enrich, Accelerate" (IDEA)

Date du début: 1 mars 2012, Date de fin: 28 févr. 2017,

...agnetic particle imaging (MPI).The IDEA project is intended to provide collaboration between scientists and clinicians from Karolinska Institute (Stockholm, Sweden), Kings College (London, UK), Paracelsus Medical University (Salzburg, Austria) and Julius-Maximilians-University (Würzburg, Germany) together with experts from SMEs specialized in photonic technologies for tissue engineering, medical d ...
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 11

 TERMINÉ 

Beta-cell function in juvenile diabetes and obesity (Beta-JUDO)

Date du début: 1 févr. 2012, Date de fin: 30 nov. 2016,

The number of individuals with obesity and type 2 diabetes mellitus (T2DM) is increasing. An alarming aspect is decline in age of onset of T2DM, which is coupled to rise in childhood obesity. Accentuated insulin secretion is observed early in young obese individuals. In many subjects insulin hypersecretion is evident when insulin sensitivity is essentially normal. Based on these observations we pr ...
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 12

 TERMINÉ 

Trail for health Sviluppo prodotto turistico turismo e salute TRAIL FOR HEALTH Gesundheitstourismus als touristisches Ganzjahresprodukt (gesundheit11)

Date du début: 31 déc. 2011, Date de fin: 30 déc. 2014,

La Valle di Tures ed Aurina, nonché le regioni dei parchi nazionali Oberpinzgau e Alti Tauri in Carinzia dispongono di un alto potenziale di risorse naturali di carattere salutistico, le quali, se propriamente rese accessibili ed utilizzate, possono essere la base per un nuovo slancio regionale in campo economico, basato su un turismo della salute con base medica certificata.Nelle tre regioni part ...
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 4

 TERMINÉ 

Development of novel nanotechnology based diagnostic systems for Rheumatoid Arthritis and Osteoarthritis (NanoDiaRA)

Date du début: 1 févr. 2010, Date de fin: 31 janv. 2014,

Based on the clinical unmet needs and recent research in biomarkers on Rheumatoid Arthritis (RA) and Osteoarthritis (OA) the main objective of the project is to develop a nanotechnology based novel diagnostic tool for easy and early detection of biomarkers in inflammatory diseases especially RA and OA by using modified superparamagnetic nanoparticles (SPION) for (A) bioassay (ex-vivo application) ...
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 10

 TERMINÉ 

Proteomics & Epi-Genetics of Anion-transport-Network (PEG-ANION-NET)

Date du début: 1 nov. 2009, Date de fin: 31 oct. 2013,

"The aim of the proposal is to fortify and intensify the scientific exchange and connectivity between four groups - two in Europe (European consortium) and two in the USA - that have a proven record in collaboration over the past years. The common theme, on which the scientific collaborations are based, is “Proteomics & Epi-Genetics of Anion transport” (PEG-Anion). Epi-Genetics refers to how inher ...
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 1

 TERMINÉ 

Learning from International Networks about Errors and Understanding Safety in Primary Care (LINNEAUS EURO -PC)

Date du début: 1 mars 2009, Date de fin: 31 mai 2013,

There is a deficit in activity related to patient safety in primary care and the primary care/secondary care interface in Europe. This deficit relates to research, to sharing of information, to learning and to collaboration.This co-ordination action will specifically address issues addressed in the call through: (1)The development of a taxonomy of adverse events and errors. (2) Identifying best cl ...
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 12

 TERMINÉ 

Developing and validating disease management evaluation methods for European health care systems (DISMEVAL)

Date du début: 1 janv. 2009, Date de fin: 31 déc. 2011,

Chronic health conditions that impose a heavy burden on society and account for a large share of health care costs. Better prevention and management could potentially decrease costs and improve quality of care and health outcomes. An important means of accomplishing these goals is through the use of disease management (DM) interventions that educate patients about prevention and health management ...
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 10