Plus de 40 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
SPIDIA for Personalized Medicine - Standardisation of generic Pre-analytical procedures for In-vitro DIAgnostics for Personalized Medicine (SPIDIA4P)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
...results unreliable or even impossible. To tackle this, SPIDA4P aims to generate and implement a comprehensive portfolio of 22 pan-European pre-analytical CEN/Technical Specifications and ISO/International Standards, addressing the important pre-analytical workflows applied to personalized medicine. These will also applicable to biomarker discovery, development and validation as well as to biobanks ...
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21
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TERMINÉ
European HIV Vaccine Alliance (EHVA): a EU platform for the discovery and evaluation of novel prophylactic and therapeutic vaccine candidates (EHVA)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,
Many HIV vaccine concepts and several efficacy trials have been conducted in the prophylactic and therapeutic fields with limited success. There is an urgent need to develop better vaccines and tools predictive of immunogenicity and of correlates of protection at early stage of vaccine development to mitigate the risks of failure. To address these complex and challenging scientific issues, the Eur ...
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43
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TERMINÉ
Advanced solutions for assuring the overall authenticity and quality of olive oil (OLEUM)
Date du début: 1 sept. 2016, Date de fin: 31 août 2020,
...alibration of the sensory panels coupled with rapid screening tools to facilitate the work of the panelists. The most promising OLEUM solutions will be subjected to VALIDATION in conformity with internationally agreed standards by peer laboratories. OLEUM will recreate a realistic “deodorization scenario” by producing tailored, soft deodorized OOs by lab-scale and up-scaled pilot plants to apply a ...
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24
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TERMINÉ
Breast Cancer Risk after Diagnostic Gene Sequencing (BRIDGES) (BRIDGES)
Date du début: 1 sept. 2015, Date de fin: 31 août 2020,
Breast cancer affects more than 360,000 women per year in the EU and causes more than 90,000 deaths. Identification of women at high risk of the disease can lead to disease prevention through intensive screening, chemoprevention or prophylactic surgery. Breast cancer risk is determined by a combination of genetic and lifestyle risk factors. The advent of next generation sequencing has opened up th ...
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20
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TERMINÉ
Integrated and innovative key actions for mycotoxin management in the food and feed chain (MycoKey)
Date du début: 1 avr. 2016, Date de fin: 31 mars 2020,
...along food and feed chains. The project will contribute to reduce mycotoxin contamination mainly in Europe and China, where frequent and severe mycotoxin contaminations occur in crops, and where international trade of commodities and contaminated batches are increasing. MycoKey will address the major affected crops maize, wheat and barley, their associated toxigenic fungi and related mycotoxins (a ...
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32
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TERMINÉ
Combatting Bacterial Resistance in Europe - Carbapenem Resistance (COMBACTE-CARE)
Date du début: 1 mars 2015, Date de fin: 28 févr. 2020,
...m-negative bacteria (MDR-GNB): the ultimate challenge!Antibiotic resistance is a global public health concern recently elevated to the top three threats identified by the WHO, and subject of numerous national and international government activities. Although focused strategies have beneficially influenced infection rates due to methicillin resistant Staphylococcus aureus (MRSA), infections due to ...
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23
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TERMINÉ
European Gram Negative Antibacterial Engine (ENABLE)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2020,
The intensive use and misuse of antibiotics has resulted in some level of antibiotic resistance in essentially all human bacterial pathogens. There is a growing concern that the loss of therapeutic options will present us with a post-antibiotic era where present and future medical advances are negated. Resistant bacteria dramatically reduce the possibilities of treating infections effectively, a ...
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42
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TERMINÉ
Imaging the Force of Cancer (FORCE)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,
Cancer is the second leading cause of mortality in EU member states with ~90% of all cancer deaths caused by metastatic spread. Despite its significance, measuring metastatic potential as well as potential indicators of therapy efficacy remain unmet clinical challenges. Recently, it has been demonstrated in vitro, that aggressive metastatic cells pull on their surroundings suggesting that metastat ...
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18
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TERMINÉ
European Initiative to Enable Validation for Highly Automated Safe and Secure Systems (ENABLE-S3)
Date du début: 1 mai 2016, Date de fin: 30 avr. 2019,
ENABLE-S3 will pave the way for accelerated application of highly automated and autonomous systems in the mobility domains automotive, aerospace, rail and maritime as well as in the health care domain. Virtual testing, verification and coverage-oriented test selection methods will enable validation with reasonable efforts. The resulting validation framework will ensure Europeans Industry competiti ...
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76
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TERMINÉ
RNA-based technologies for single-cell metabolite analysis (MetaRNA)
Date du début: 1 janv. 2015, Date de fin: 31 déc. 2018,
Metabolism is the foundation of all living organisms. While cells in a population are often phenotypically different, most of our current analytical approaches still probe metabolism only at the population level. Because strong evidence exists that metabolic cell-to-cell heterogeneity has, for instance, disease relevance, researcher from MetaRNA will overcome this severe analytical limitation thro ...
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11
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TERMINÉ
TBVAC2020; Advancing novel and promising TB vaccine candidates from discovery to preclinical and early clinical development (TBVAC2020)
Date du début: 1 janv. 2015, Date de fin: 31 déc. 2018,
...B vaccine and biomarker pipeline as well as accelerate development of most promising TB vaccine candidates through early development stages. The proposed approach and involvement of many internationally leading groups in the TB vaccine and biomarker area in TBVAC2020 fully aligns with the Global TB Vaccine Partnerships (GTBVP).
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49
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TERMINÉ
Human Brain Project Specific Grant Agreement 1 (HBP SGA1)
Date du début: 1 avr. 2016, Date de fin: 31 mars 2018,
...d the capabilities of the HBP Platforms, in order to use them to address otherwise intractable problems in neuroscience, computing and medicine in the future. In addition, collaborations with other national, European and international initiatives will create synergies, maximizing returns on research investment. SGA1 covers the detailed steps that will be taken to move the HBP closer to achieving i ...
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126
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TERMINÉ
European Medical Information Framework (EMIF)
Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,
In response to the need to tackle increasingly complex medical research questions, a growing amount of human health data is being collected, either in routine Electronic Healthcare Record (EHR) databases, through research-driven cohort studies, in biobanks or related efforts. However, data sources are typically fragmented and contain information gaps which prevent their full exploitation. EMIF aim ...
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64
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TERMINÉ
European Clinical Research Infrastructures Network - Integrating Activity (ECRIN-IA)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2017,
ECRIN is a distributed ESFRI-roadmap pan-European infrastructure designed to support multinational clinical research, making Europe a single area for clinical studies, taking advantage of its population size to access patients. Servicing multinational trials started during its preparatory phase, and it now applies for an ERIC status by 2011. The ERIC budget will be restricted to core activities re ...
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48
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TERMINÉ
European Research Infrastructures for Poverty Related Diseases (EURIPRED)
Date du début: 1 nov. 2013, Date de fin: 31 oct. 2017,
...e presents a prime opportunity to address other sexually transmitted diseases such as viral hepatitis efficiently and effectively. The overall goal of the EURIPRED is to coordinate and integrate international resources into a single specialised infrastructure to support European HIV, TB, Malaria and Hepatitis B virus and Hepatitis C virus studies from early drug, vaccine and microbicide discovery ...
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18
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TERMINÉ
Advanced Immunization Technologies (ADITEC)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2017,
Vaccines so far have been developed mostly by following an empiric approach. To prevent and possibly cure unresolved and emerging infectious diseases we need to fully exploit the potential of the human immune system. Progress in science and technology makes it possible to achieve what was previously deemed impossible. The scope of this project is to produce knowledge necessary to develop novel and ...
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53
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TERMINÉ
European Initial Training Network on Developmental and Computational Biology (DevCom)
Date du début: 1 sept. 2013, Date de fin: 31 août 2017,
The ability to manipulate cellular pluripotency and differentiation holds the as yet unrealized promise of regenerative medicine to produce replacement cells and tissues. To this end a deep understanding of the regulation of differentiation potential in the context of normal embryonic development is crucial. The recent revolution in sequencing technology has enabled high throughput and genome-wide ...
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8
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TERMINÉ
Embedded Multi-Core Systems for Mixed Criticality Applications in Dynamic and Changeable Real-Time Environments (EMC2)
Date du début: 1 avr. 2014, Date de fin: 30 juin 2017,
...lications in dynamic and changeable real-time environments.The EMC2 project focuses on the industrialization of European research outcomes and builds on the results of previous ARTEMIS, European and National projects. It provides the paradigm shift to a new and sustainable system architecture which is suitable to handle open dynamic systems.EMC² is part of the European Embedded Systems industry st ...
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101
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TERMINÉ
Vaccination against Shigella and ETEC: novel antigens, novel approaches (STOPENTERICS)
Date du début: 1 nov. 2010, Date de fin: 30 avr. 2017,
To contribute to the development of vaccines against Shigella and ETEC for children of the developing world, STOPENTERICS will provide novel solutions by imposing a two-fold paradigm switch: (i) to break the dogma of serotype-specificity by inducing a cross-protective immunity (ii) to improve the immunogenicity of Shigella glycoconjugates by using synthetic oligosacharides mimicking the lipopolysa ...
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20
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TERMINÉ
Integrated Approaches to Food Allergen and Allergy Risk Management (IFAAM)
Date du début: 1 mars 2013, Date de fin: 28 févr. 2017,
Up to 20 million European citizens suffer from food allergy. However management of both food allergy (by patients and health practitioners) and allergens (by industry) is thwarted by lack of evidence to either prevent food allergy developing or protect adequately those who are already allergic. iFAAM will develop evidence-based approaches and tools for MANAGEMENT of ALLERGENS in FOOD and integrate ...
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46
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TERMINÉ
European multicentre, randomised, phase III clinical trial of hypothermia plus best medical treatment versus best medical treatment alone for acute ischaemic stroke (EuroHYP-1)
Date du début: 1 févr. 2012, Date de fin: 31 janv. 2017,
The consortium led by UKER and EuroHYP, the European Stroke Research Network for Hypothermia, proposes a large, multicentre clinical trial which will assess mild hypothermia as a novel treatment for ischemic stroke.Stroke is the second cause of death world-wide and the second cause of lost disability-adjusted life years in high-income countries. Stroke incidence rises exponentially with age, so it ...
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38
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TERMINÉ
Integrating Post-Abortion Family Planning Services into China's existing abortion service in hospital settings (INPAC)
Date du début: 1 août 2012, Date de fin: 31 janv. 2017,
In 2008 an estimated 13 million induced abortions were conducted in China. Induced abortions are associated with a high risk of injury or long-term physical and psychological morbidity and a heavy social and economic burden. Most abortions occur in cities and the epidemic affects young and unmarried women as well as rural-to-urban migrant women.The large number of abortions is primarily due to con ...
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7
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TERMINÉ
African Vector Control: New Tools (AvecNet)
Date du début: 1 févr. 2011, Date de fin: 31 déc. 2016,
...ol and elimination. Our carefully balanced, multidisciplinary team of European and African experts includes vector biologists, engineers, epidemiologists, social scientists and leaders of large supranational consortia. These partners are all prominent members of global vector control research programs having unique specialization in Africa-centric projects.Together we have developed a proposal f ...
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17
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TERMINÉ
PRIMES: Protein interaction machines in oncogenic EGF receptor signalling (PRIMES)
Date du début: 1 déc. 2011, Date de fin: 30 nov. 2016,
"PRIMES focuses on the role of protein interactions to assemble dynamic molecular machines that receive and process information to coordinate cellular responses. PRIMES investigates the following: (i) How do protein interactions contribute to the generation of biological specificity in signalling? (ii) How do pathogenetic perturbations affect protein interaction networks? (iii) How can we exploit ...
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14
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TERMINÉ
The Human Brain Project (HBP)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2016,
... for collaboration that links the partners under strong scientific leadership and professional project management, providing a coherent European approach and ensuring effective alignment of regional, national and European research and programmes. The project work plan is organized in the form of thirteen subprojects, each dedicated to a specific area of activity.A significant part of the budget wi ...
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116
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TERMINÉ
Kinetoplastid Drug Development: strengthening the preclinical pipeline (KINDRED)
Date du début: 1 sept. 2013, Date de fin: 31 août 2016,
The trypanosomatid diseases, leishmaniasis, Human African trypanosomiasis (HAT) and Chagas disease (CD), continue to impart a heavy toll on human health. The treatments available are limited and threatened by drug resistance with few newdrugs in the pipeline. The KINDReD consortium integrates five leading academic laboratories in Europe (Portugal, United Kingdom, and Switzerland), the USA (Califor ...
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14
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TERMINÉ
Application of new technologies and methods in nutrition research – the example of phenotypic flexibility (NutriTech)
Date du début: 1 janv. 2012, Date de fin: 30 juin 2016,
NutriTech will build on the foundations of traditional human nutrition research using cutting-edge analytical technologies and methods to comprehensively evaluate the diet-health relationship and critically assess their usefulness for the future of nutrition research and human well-being. Technologies include genomics, transcriptomics, proteomics, metabolomics, laser scanning cytometry, NMR based ...
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25
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TERMINÉ
Systems biology of liver cancer: an integrative genomic-epigenomic approach (MODHEP)
Date du début: 1 janv. 2011, Date de fin: 30 juin 2016,
"Cancer is a complex disease involving multiple genetic and epigenetic events occurring, and influencing each other, over a long period of time. Understanding cancer, and ultimately developing effective targeted therapies, will therefore require that mutations and epigenetic alterations be systematically investigated during the multiple stages of disease development, from identifiable pre-neoplast ...
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18
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TERMINÉ
Prospective cohort study of residents near the Semipalatinsk nuclear test site - feasibility (SEMI-NUC)
Date du début: 1 avr. 2013, Date de fin: 31 mars 2016,
...pulations residing around the Semipalatinsk nuclear test site and/or who have been extensively involved in the low dose risk research. The group will include European and international scientists with expertise in epidemiology, dosimetry, radiation biology and clinical medicine. At the end of the project, a detailed report based on the results of the work conducted will be developed, critically re ...
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8
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TERMINÉ
Electronic Health Record systems for Clinical Research (EHR4CR)
Date du début: 1 mars 2011, Date de fin: 29 févr. 2016,
Current medical needs, the growth of targeted therapies and personalized medicines, and escalating R&D costs result in formidable cost pressures on healthcare systems and the pharmaceutical industry. Clinical research is also growing in complexity, labour intensity and cost. There is a growing realization that the development and integration of Electronic Health Record systems (EHRs) for medical ...
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37
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TERMINÉ
European Research Training in the Ubiquitin Proteasome System (UPStream)
Date du début: 1 nov. 2011, Date de fin: 31 oct. 2015,
The main objective of the international training network UPStream is the training of a novel generation of European scientist in a critical and complex field of modern biology: the understanding of the regulation of the UPS and its potential use for drug development. The importance of this process is illustrated by the imperious necessity to destroy certain proteins during several phases of the ce ...
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10
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TERMINÉ
Dissecting the Immunological Interplay between Poverty Related Diseases and Helminth Infections: An African-European Research Initiative (IDEA)
Date du début: 1 mars 2010, Date de fin: 31 août 2015,
Worm infections are receiving increased attention due to: the wide geographic overlap in occurrence between worms and HIV, TB and malaria; the large proportion of individuals (minimal estimates around 25%) co-infected with worms and HIV/TB/ malaria; the potential risk of increasing disease burden; the very limited understanding of the impact by worm infections on HIV-, TB- and malaria-specific imm ...
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23
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TERMINÉ
Overcoming clinical relapse in multiple myeloma by understanding and targeting the molecular causes of drug resistance (OVER-MYR)
Date du début: 1 janv. 2012, Date de fin: 30 juin 2015,
...subpopulations of MMCii) drugs induce alterations in cells of the ‘niche’ that promote drug-resistance.OVER-MYR integrates a network of outstanding researchers from 6 EU countries with internationally recognized experience in clinics and human and animal models of MM, who will jointly:WP1: Study the molecular alterations in primary MM and environment cells in samples obtained from a large number o ...
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11
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TERMINÉ
Open Collaborative Model for Tuberculosis Lead Optimisation (ORCHID)
Date du début: 1 janv. 2011, Date de fin: 30 juin 2015,
"Early stage Drug Discovery efforts over the last 5 years have resulted in the identification of a number of promising lead compounds in the fight against TB. These leads need to be further progressed and optimised into candidates for pre-clinical development through the Drug Development progression cascade.Three compound families are of particular interest: 1) InhA Inhibitors, 2) New potent whole ...
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14
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TERMINÉ
Semantic Interoperability for Health Network (SemanticHealthNet)
Date du début: 1 déc. 2011, Date de fin: 31 mai 2015,
...ive, will inform the shape of the Virtual Organisation that this Network will establish to sustain semantic interoperability developments and their adoption.The consortium comprises more than 40 internationally recognised experts, including from USA and Canada, ensuring a global impact.
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18
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TERMINÉ
Health, environmental change and adaptive capacity: mapping, examining and anticipating future risks of water-related vector-borne diseases in eastern Africa (HEALTHY FUTURES)
Date du début: 1 janv. 2011, Date de fin: 31 déc. 2014,
The HEALTHY FUTURES project is motivated by concern for the health impacts of environmental changes. HEATHLY FUTURES aims to respond to this concern through construction of a disease risk mapping system for three water-related high-impact VBDs (malaria, Rift valley fever and schistosomiasis) in Africa, accounting for environmental/climatic trends and changes in socio-economic conditions to predic ...
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17
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TERMINÉ
Environmental and Economic BEnefits from BIochar clusterS in the Central area (E2BEBIS)
Date du début: 31 mai 2012, Date de fin: 29 nov. 2014,
....The E2BEBIS project aims at developing regional energy clusters adopting the biochar technology, and at advancing the related policies through its full legal adoption by competent authorities at the national and the EU level. The transnational Central dimension helps considering the adoption of such technology in context featuring different environmental conditions, different types of biomass, di ...
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8
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TERMINÉ
Health Education and Community Integration: Evidence based Strategies to increase equity, integration and effectiveness of reproductive health services for poor communities in Sub Saharan Africa (INTHEC)
Date du début: 1 mars 2010, Date de fin: 31 août 2014,
Objectives: The research aims to improve the delivery of reproductive health (RH) services in Tanzania and Niger by generating new evidence about effective ways to strengthen the provision, uptake, equity and effectiveness of adolescent reproductive health (ARH) programmes. Background: Poor adolescent reproductive health (ARH) continues to be a major cause of morbidity and worsening poverty for th ...
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8
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TERMINÉ
The targeted development of a new generation Vaccine for Schistosomiasis (TheSchistoVac)
Date du début: 1 févr. 2010, Date de fin: 31 juil. 2014,
The aim of this project is to develop a new generation vaccine for schistosomiasis. The vaccine will be based on exposed proteins and/or glycans of the vulnerable skin stage schistosomula, making it safe and effective. The life stage-specific vaccine target selection strategy is based on state-of-the-art schistosomal transcriptomics and glycomics technologies and data, and unique serum and sample ...
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14
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TERMINÉ
PLANT food supplements: Levels of Intake, Benefit and Risk Assessment (PlantLIBRA)
Date du début: 1 juin 2010, Date de fin: 31 mai 2014,
...information and better tools (e.g., metadatabanks). PlantLIBRA is structured to develop, validate and disseminate data and methodologies for risk and benefit assessment and implement sustainable international cooperation. International cooperation, on-spot and in-language capacity building are necessary to ensure the quality of the plants imported in the EU. PlantLibra spans 4 continents and 23 pa ...
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