3 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Synthetic bacterial lipid rafts to optimize industrial bioprocesses (Rafts4Biotech)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
Genetic tractability of bacterial cells allows generating synthetic microbial chassis platforms (SMCPs) with remarkable biotechnological applications but their functionality currently faces important off-genome limitations due to deficient protein-protein interactions, unfavorable protein stoichiometry or generation of toxic intermediates that ultimately compromise the industrial production proces ...
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13
Participants partenaires
TERMINÉ
An integrated mulTidisciplinary appRoach towards a new generAtIon of aNtibiotics: Targeting function and cross-talk of bacterial Envelope proTein machineries (Train2Target)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
Train2Target is a multidisciplinary European Training Network built to address the challenge of the discovery of alternative antimicrobials. Innovative strategies to deliver a next generation of drugs are urgently needed. The alarming threats and spread of multi-drug resistant bacteria is currently leaving clinicians with very limited options to combat infections especially those from Gram-negativ ...
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11
Participants partenaires
TERMINÉ
Thoroughly Optimised Production Chassis for Advanced Pharmaceutical Ingredients (TOPCAPI)
Date de fin: 1 janv. 2017,
TOPCAPI will exploit the natural fabrication power of actinomycetes as microbial cell factories to produce three high value compounds: GE2270, a starter compound for the semi-synthesis of NAI-Acne, a new topical anti-acne drug in Phase II clinical trials; 6-desmethyl-tetracycline (6DM-TC) and 6-desmethyl 6-deshydro tetracycline (6DM6DH-TC), intermediates for semi-synthetic conversion to medically ...
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