2 projets européens trouvés
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TERMINÉ
Cardiomics: Use of -omics methods in large populations for identification of novel drug targets and clinical biomarkers for coronary heart disease (CARDIOMICS)
Date du début: 1 janv. 2014, Date de fin: 31 déc. 2018,
There is a large need for revitalization of the research on coronary heart disease (CHD) including: a) improved risk prediction and more adequate individually-tailored treatment; and b) new targets for drug development based on pathways previously unknown to be involved in CHD pathophysiology.The overall goal of this proposal is to improve prevention and treatment of CHD through better understandi ...
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TERMINÉ
Personalisation of tREatment In Cardiovascular disease through next generation sequencing in Adverse Drug Reactions (PREDICTION-ADR)
Date du début: 1 sept. 2013, Date de fin: 28 févr. 2017,
Prediction-ADR aims to discover the genetic factors predisposing patients to adverse drug reactions (ADRs) from cardiovascular disease (CVD) drugs. This will be achieved by assembling a consented blood bank and DNA for a population of ~500 cases of ACEi induced angioedema and statin induced myopathy defined using a standardised phenotypic criteria. An innovative next generation sequencing strategy ...
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